Results 331 to 340 of about 71,170 (384)
Some of the next articles are maybe not open access.
Journal of Drugs in Dermatology, 2021
Psoriasis is polygenic, interleukin (IL)-17 and IL-23 driven chronic relapsing inflammatory multisystem disease caused by a complex interplay of endogenous and environmental factors. The most common and distressing symptom in psoriasis is itch, adding significantly to the burden of disease.
Swathi Shivakumar +6 more
openaire +2 more sources
Psoriasis is polygenic, interleukin (IL)-17 and IL-23 driven chronic relapsing inflammatory multisystem disease caused by a complex interplay of endogenous and environmental factors. The most common and distressing symptom in psoriasis is itch, adding significantly to the burden of disease.
Swathi Shivakumar +6 more
openaire +2 more sources
Dermatologic Clinics, 2001
In the 1990s, major improvements occurred in the therapeutic index of H1 antihistamines. The third-generation compounds promise to be more effective and nontoxic. The future major advances are likely to result from development and exploitation of non-H1 receptor-mediated antiallergic actions of these drugs.
openaire +2 more sources
In the 1990s, major improvements occurred in the therapeutic index of H1 antihistamines. The third-generation compounds promise to be more effective and nontoxic. The future major advances are likely to result from development and exploitation of non-H1 receptor-mediated antiallergic actions of these drugs.
openaire +2 more sources
Anaesthesia & Intensive Care Medicine, 2008
Abstract Histamine is one of the most extensively studied biological amines in medicine. It stimulates smooth muscle contraction and gastric acid secretion, increases vascular permeability, functions as a neurotransmitter, and plays various roles in immunomodulation, allergy, inflammation, haematopoiesis and cell proliferation.
Nigel R. Webster, Amr M. Mahdy
openaire +2 more sources
Abstract Histamine is one of the most extensively studied biological amines in medicine. It stimulates smooth muscle contraction and gastric acid secretion, increases vascular permeability, functions as a neurotransmitter, and plays various roles in immunomodulation, allergy, inflammation, haematopoiesis and cell proliferation.
Nigel R. Webster, Amr M. Mahdy
openaire +2 more sources
International Forum of Allergy and Rhinology, 2018
A combination of H1 antihistamine (AH) with intranasal corticosteroid (INCS) is commonly prescribed to patients with allergic rhinitis (AR) who have an inadequate response to monotherapy.
K. Seresirikachorn +4 more
semanticscholar +1 more source
A combination of H1 antihistamine (AH) with intranasal corticosteroid (INCS) is commonly prescribed to patients with allergic rhinitis (AR) who have an inadequate response to monotherapy.
K. Seresirikachorn +4 more
semanticscholar +1 more source
2014
The discovery of histamine, its physiological role and reversal of its pharmacological effects by antihistamines takes us on a journey through the origins of modern physiology and the rising understanding of pharmacology at the end of the 19th and the early part of the 20th centuries.
Martin K, Church, Marcus, Maurer
openaire +2 more sources
The discovery of histamine, its physiological role and reversal of its pharmacological effects by antihistamines takes us on a journey through the origins of modern physiology and the rising understanding of pharmacology at the end of the 19th and the early part of the 20th centuries.
Martin K, Church, Marcus, Maurer
openaire +2 more sources
Anaesthesia & Intensive Care Medicine, 2021
Abstract Histamine is one of the most important and extensively studied biological molecules in the human body. It plays a constitutive role within almost every bodily system, but most notably within the stomach, where it regulates acid secretion, the central nervous system, where it acts as a neurotransmitter, the cardiovascular system, where it ...
Peter Ruether +3 more
openaire +2 more sources
Abstract Histamine is one of the most important and extensively studied biological molecules in the human body. It plays a constitutive role within almost every bodily system, but most notably within the stomach, where it regulates acid secretion, the central nervous system, where it acts as a neurotransmitter, the cardiovascular system, where it ...
Peter Ruether +3 more
openaire +2 more sources
Journal of Allergy and Clinical Immunology, 1989
Substantial evidence indicates that airway hyperresponsiveness in asthma is associated with the inflammatory response directed toward the airway epithelium and submucosa. Endogenously released spasmogenic mediators interacting with smooth muscle have a greater effect on hyperresponsive than on normal airways.
J.P. Finnerty, Stephen T. Holgate
openaire +3 more sources
Substantial evidence indicates that airway hyperresponsiveness in asthma is associated with the inflammatory response directed toward the airway epithelium and submucosa. Endogenously released spasmogenic mediators interacting with smooth muscle have a greater effect on hyperresponsive than on normal airways.
J.P. Finnerty, Stephen T. Holgate
openaire +3 more sources
Hypersensitivity to antihistamines
Allergy and Asthma Proceedings, 2013Antihistamines are the cornerstone of allergy therapy and are not expected to cause hypersensitivity reactions. We describe two cases, one had urticaria to multiple anti-H1-preparations and the other had anaphylaxis to hydroxyzine. We also provide a review of the English literature on reported reactions regarding causative preparations and ...
Alireza A. Shakouri, Sami L. Bahna
openaire +3 more sources
Journal of the American Medical Association, 1947
Any medicament, no matter how valuable, may do great harm if it is employed indiscriminately. The fame of the new antihistaminic drugs has become so widespread, indeed, that they are often prescribed merely to satisfy the patient's curiosity. A critical inventory of their value is therefore indicated.
openaire +4 more sources
Any medicament, no matter how valuable, may do great harm if it is employed indiscriminately. The fame of the new antihistaminic drugs has become so widespread, indeed, that they are often prescribed merely to satisfy the patient's curiosity. A critical inventory of their value is therefore indicated.
openaire +4 more sources
Antihistamines and decongestants [PDF]
Otolaryngology–Head and Neck Surgery, 1992 Drug therapy for allergic rhinitis is used either to prevent symptoms from occurring by short‐circuiting the reaction and thus inhibiting the production of chemical mediators or to control symptoms after the target organs have been stimulated by these mediators.
openaire +2 more sources