Results 101 to 110 of about 302,854 (293)

Thiocarbamoylimidates as Precursors of New 5‐Amino‐1,2,4‐Triazole and Oxadiazole Derivatives In Silico Prediction of Absorption, Distribution, Metabolism, and Excretion Parameters

ChemPlusChem, EarlyView.
1,2,4‐triazole and oxadiazole motifs are synthesized from thiocarbamoylimidates precursors, under mild conditions (40 °C) in the environmentally friendly water/ethanol reaction medium. The reaction is highly versatile and allows for the introduction of a wide variety of functional groups.
Oumaima Gatri, Thierry Roisnel, Marie Cordier, Vincent Dorcet, Mohamed Lotfi Efrit, Cédric Fischmeister   +5 more
wiley   +1 more source

Impact of a Workplace Stress Reduction Program on Blood Pressure and Emotional Health in Hypertensive Employees [PDF]

, 2003
This study examined the impact of a workplace-based stress management program on blood pressure (BP), emotional health, and workplace-related measures in hypertensive employees of a global information technology ...
Dana Tomasino, Mike Atkinson, Rollin McCraty   +2 more
core   +1 more source

Results of the ACCOuNT Trial: A Multi‐Institutional Prospective Pharmacogenomics Implementation Trial for African American Inpatients

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenomics implementation efforts have increased over the last decade, but no published prospective pharmacogenomics trials have formally evaluated utility in underrepresented populations. We present final results from the ACCOuNT trial, a multi‐institutional prospective study [NCT03225820] in which African American inpatients were genotyped and ...
Zhong Huang, Kevin J. O'Leary, Edith A. Nutescu, Matthew Jack, Thomas Chen, Gregory W. Ruhnke, James C. Lee, David George, Larry K. House, Randall Knoebel, Luke V. Rasmussen, Seth Hartman, Anish Choksi, Kiang‐Teck J. Yeo, Minoli A. Perera, Mark J. Ratain, David O. Meltzer, Peter H. O'Donnell   +17 more
wiley   +1 more source

Relationship between cardiovascular risk and lipid testing in one health care system: a retrospective cohort study. [PDF]

, 2015
BackgroundThe US Preventive Services Taskforce (USPSTF) recommends routine lipid screening beginning age 35 for men [1]. For women age 20 and older, as well as men age 20-34, screening is recommended if cardiovascular risk factors are present.
Anderson, Melissa L, Catz, Sheryl L, Fishman, Paul A, Green, Beverly B, Johnson, Ron L, McClure, Jennifer B, Reid, Robert J   +6 more
core   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and Risk of Gastrointestinal Bleeding: A Systematic Review and Meta‐Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik, Ainhoa Gomez‐Lumbreras, Guilherme Del Fiol, Kensaku Kawamoto, Katy E. Trinkley, Thomas Reese, Aubrey Jones, Daniel C. Malone   +7 more
wiley   +1 more source

A Differential Response to Antihypertensive Therapy in African Men and Women: Insights From the CREOLE Trial [PDF]

, 2022
Dike Ojji, Gabriel Shedul, Mahmoud U. Sani, Okechukwu S. Ogah, Anastase Dzudié, Felix Barasa, Charles Mondo, Prossie Merab Ingabire, Erika Jones, Brian Rayner, Damasceno Albertino, Elijah Ogola, Wynand Smythe, Nicky Hickman, Veronica Francis, Shahiemah Pandie, Grace Shedul, Akinyemi Aje, Karen Sliwa, Simon Stewart   +19 more
openalex   +1 more source

Impact of Antihypertensive Treatment on Outcomes of Adjuvant Bevacizumab for Ovarian Cancer (IATRO), Results from a Nationwide Emulated Clinical Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Antiangiogenic therapy with bevacizumab improves outcomes in ovarian cancer but induces hypertension, leading to major adverse cardiovascular events (MACE). While calcium channel blockers (CCBs) and angiotensin‐converting enzyme inhibitors (ACEi) are recommended for managing bevacizumab‐associated hypertension, their impacts on cancer progression and ...
Floriane Jochum, Élise Dumas, Joe‐Elie Salem, Stéphane Ederhy, Anne‐Sophie Hamy, Lise Lecointre, Enora Laas, Fabien Reyal, Fabrice Lecuru, Cherif Akladios, Paul Gougis   +10 more
wiley   +1 more source

Theory-based predictors of multiple clinician behaviors in the management of diabetes [PDF]

, 2015
Peer ...
Eccles, Martin P, Elovainio, Marko, Francis, Jill J, Grimshaw, Jeremy M, Hawthorne, Gillian, Hrisos, Susan, Hunter, Margaret, Johnston, Marie, Presseau, Justin, Stamp, Elaine, Steen, Nick   +10 more
core   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

Clinical Pharmacology &Therapeutics, EarlyView.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan, Lynn Miller, Sam Wade, Jenni Ilomäki, Dickson Lukose, Jia Rong, Geoffrey I. Webb   +6 more
wiley   +1 more source

PROFIL PENGGUNAAN OBAT PASIEN HIPERTENSI ESENSIALDI INSTALASI RAWAT JALAN RUMAH SAKIT UMUM DAERAH I LAGALIGO KABUPATEN LUWU TIMUR PERIODE JANUARI-DESEMBER TAHUN 2014

Jurnal Farmasi Galenika (Galenika Journal of Pharmacy), 2017
This study aimed to determine the demographic and clinical characteristics and profile of drug use in patients with essential hypertension at outpatient installations I Lagaligo General Hospital East Luwu Regency period January-December 2014.
Senfri Tandililing, Alwiyah Mukaddas, Ingrid Faustine   +2 more
doaj   +1 more source