Results 181 to 190 of about 302,854 (293)

A “One‐Pot” Metal‐Free Synthesis and Evaluation of Antiproliferative Activity of Diversely Functionalized Pyrrolidine‐2‐Ones

open access: yesJournal of Heterocyclic Chemistry, EarlyView.
A new “one‐pot” metal‐free stereoselective method for the synthesis of novel diversely functionalized pyrrolidine‐2‐ones from N‐alkyl‐ or N‐arylsulfonamidoacetophenones was developed. The majority of obtained compounds possess low micromolar antiproliferative activities.
Samuel Dick   +7 more
wiley   +1 more source

Should the non‐canonical pathway of nitric oxide generation be targeted in hypertensive pregnancies?

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Hypertension in pregnancy is prevalent, affecting around 10% of pregnancies worldwide, and significantly increases the risk of adverse outcomes for both mothers and their babies. Current treatment strategies for pregnant women with hypertension are limited, and new approaches for the management of hypertension in pregnancy are urgently needed.
Elizabeth C. Cottrell
wiley   +1 more source

Decision fatigue in hospital medicine: A retrospective exploratory evaluation

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background “Decision fatigue” (DF) is the deterioration in decision‐making ability stemming from repeated decision making. Objective Explore DF over the clinical workblock and across hospitalist and work characteristics. Methods Patients seen by hospitalists at two hospitals in January and February 2022 were retrospectively evaluated for ...
Rachel M. Kruer   +6 more
wiley   +1 more source

Exploring the roles and impacts of pharmacists embedded in general practice: a scoping review

open access: yesJournal of Pharmacy Practice and Research, EarlyView.
Abstract Background The role of the general practice pharmacist (GPP) in Australia is not yet clearly defined, and their clinical expertise remains underutilised in general practice settings. This may be attributed to a limited understanding of pharmacists' capabilities, which can hinder optimal GPP utilisation.
Christel Chandra   +3 more
wiley   +1 more source

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