Results 31 to 40 of about 302,854 (293)

Study on the Excretion of a New Antihypertensive Drug 221s (2,9) in Rats

open access: yesPharmaceuticals
Background/Objectives: The novel compound 221s (2,9), derived from danshensu and ACEI-active proline, exhibits antihypertensive effects (50/35 mmHg SBP/DBP reduction in SHRs) with potential cough mitigation.
Yunmei Chen   +5 more
doaj   +1 more source

A Meta-Analysis of Folic Acid in Combination with Anti-Hypertension Drugs in Patients with Hypertension and Hyperhomocysteinemia

open access: yesFrontiers in Pharmacology, 2017
Folic acid is generally used to lower homocysteine concentrations and prevent stroke and cardiovascular disease (CVD) at present. However, the efficacy of therapies that lower homocysteine concentrations in reducing the risk of CVD and stroke remains ...
Wen-Wen Wang   +4 more
doaj   +1 more source

Epidemiology of Hypertension in the Prefecture of Figuig, Morocco

open access: yesRwanda Medical Journal, 2022
BACKGROUND: Hypertension continues to be a public health problem with devastating consequences globally, particularly in developing countries where there is an acute paucity of hypertension data. The aim of this study was to describe the epidemiological,
E. Rida   +3 more
doaj   +1 more source

Toxicity Profiling and In Vivo Metabolism of Danshensu-Derived Novel Antihypertensive Candidate 221s (2,9)

open access: yesToxins
Compound 221s (2,9) is a novel antihypertensive drug candidate synthesized utilizing danshensu, borneol, and proline by using the strategy of combinatorial molecular chemistry.
Yunmei Chen   +5 more
doaj   +1 more source

Antihypertensive Medication Regimens Used by US Adults With Hypertension and the Potential for Fixed‐Dose Combination Products: The National Health and Nutrition Examination Surveys 2015 to 2020

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Fixed‐dose combination (FDC) antihypertensive products improve blood pressure control and adherence among patients with hypertension. It is unknown to what degree commercially available FDC products meet the current hypertension management ...
Catherine G. Derington   +8 more
doaj   +1 more source

Synthesis and Antifungal Activity of 1,2,4-Oxadiazole Derivatives

open access: yesMolecules
1,2,4-Oxadiazole derivatives containing anisic acid or cinnamic acid were designed and synthesized, which were expected to be an effective Succinate dehydrogenase (SDH) inhibitor, and their structures were characterized by 1H NMR, 13C NMR, and ESI-MS ...
Lili Yu   +7 more
doaj   +1 more source

Variations in Arterial Blood Pressure after Kidney Transplantation [PDF]

open access: yes, 1973
The course of hypertension within the first 2 months after kidney transplantation was correlated with renal function, plasma renin activity (PRA), and the daily maintenance dose of prednisone in 18 homograft recipients.
CORMAN, JACQUES L   +7 more
core   +1 more source

Comparing 3 Evidence‐Based Strategies to Reduce Cardiovascular Disease Burden: An Individual‐Based Cardiometabolic Policy Simulation

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Understanding the real‐world impact of clinical trials that change risk factors is important for health policy. We developed a microsimulation that estimates the population‐level benefits in each US state of cardiometabolic interventions ...
Sylvia Lutze   +13 more
doaj   +1 more source

The Hypotensive and Vasodilatory Effects Observed in Rats Exposed to Chiranthodendron pentadactylon Larreat Flowers Can Be Attributed to Cyanidin 3-O-Glucoside

open access: yesMolecules, 2023
Chiranthodendron pentadactylon Larreat is a tree native to southeastern Mexico and Guatemala. Its flower is used in Mexican folk medicine to treat a variety of diseases, including conditions of blood pressure.
Juan Luis Escobar-Ramírez   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy