Results 121 to 130 of about 112,082 (305)

Design, synthesis and in silico evaluation of newer 1,4-dihydropyridine based amlodipine bio-isosteres as promising antihypertensive agents. [PDF]

RSC Adv, 2023
Takkar P, Singh B, Pani B, Kumar R.
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Single-Pill Combination with Three Antihypertensive Agents to Improve Blood Pressure Control in Hypertension: Focus on Olmesartan-Based Combinations. [PDF]

High Blood Press Cardiovasc Prev, 2023
Burnier M, Redon J, Volpe M.
europepmc   +1 more source

Whose Care Matters? The Protective Role of Perceived Care in the Long‐Term Physical Health Consequences of Adolescent Loneliness

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Loneliness has been associated with physical health outcomes, including an increased risk of cardiovascular disease (CVD). While much of the research has focused on older adults, less is known about whether loneliness during adolescence is related to CVD risk later in life.
Keun Young Kwon, Ha Ly Choi, Skylar Biyang Sun, Xiaohang Zhao, Jinho Kim   +4 more
wiley   +1 more source

Efectos de la administración crónica de carvedilol sobre la variabilidad de la presión arterial y el daño de órgano blanco en ratas con desnervación sinoaórtica [PDF]

, 2015
Background: Increased blood pressure variability is a novel risk factor for the development of target organ injury both in hypertensive and normotensive subjects, so its reduction should be considered as a new therapeutic goal. Objective: The aim of this
Bertera, Facundo Martin, Carranza, Maria Andrea, del Mauro, Julieta Sofía, Donato, Pablo Martín, Gelpi, Ricardo Jorge, Gorzalczany, Susana Beatriz, Höcht, Christian, Santander Plantamura, Yanina Alejandra, Taira, Carlos Alberto   +8 more
core  

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Treatment of hypertension during pregnancy: a cohort of pregnancy episodes from the SIDIAP database, Catalonia, Spain

Frontiers in Pharmacology
IntroductionHypertension during pregnancy is one of the most frequent causes of maternal and fetal morbimortality. Perinatal and maternal death and disability rates have decreased by 30%, but hypertension during pregnancy has increased by approximately ...
Ainhoa Gomez-Lumbreras, Carles Vilaplana-Carnerero, Carles Vilaplana-Carnerero, Carles Vilaplana-Carnerero, Carles Vilaplana-Carnerero, Marta Lestón Vázquez, Marta Lestón Vázquez, Cristina Vedia, Cristina Vedia, Rosa Morros, Rosa Morros, Rosa Morros, Rosa Morros, Maria Giner-Soriano, Maria Giner-Soriano   +14 more
doaj   +1 more source

Prescribing Patterns of Antihypertensive Agents and Blood Pressure Control Among Patients With Incident Stage 2 Hypertension. [PDF]

J Pharm Technol, 2022
Helms MV, Edwards AL, Suszynsky TH, Hwang AY.   +3 more
europepmc   +1 more source

On‐site pilot‐scale advanced oxidation pretreatment of hospital wastewater: assessment of pharmaceuticals, pathogens, antibiotic resistance genes and acute ecotoxicity

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos, Iosifina Gounaki, Spyros Dokianakis, Georgios Gkotsis, Maria‐Christina Nika, Eleni Aleiferi, Athanasios S Stasinakis, Nikos Katsarakis, Nikolaos S Thomaidis, Thrassyvoulos Manios, Michalis S Fountoulakis, Danae Venieri   +11 more
wiley   +1 more source

How to treat arterial stiffness beyond blood pressure lowering? [PDF]

, 2011
De Backer, Tine, De Buyzere, Marc, Van Bortel, Lucas   +2 more
core   +1 more source