Results 161 to 170 of about 139,220 (339)

Treatment Selection and Prioritization for the EJS ACT‐PD MAMS Trial Platform

Movement Disorders, EarlyView.
Abstract Background There are currently no disease‐modifying therapies (DMTs) registered for Parkinson's disease (PD). The Edmond J. Safra Accelerating Clinical Trials in Parkinson Disease (EJS ACT‐PD) initiative will expedite clinical assessment of putative DMTs through a multi‐arm multistage (MAMS) trial, testing several treatments against a common ...
Cristina Gonzalez‐Robles, Dilan Athauda, Thomas R. Barber, Roger A. Barker, David T. Dexter, Susan Duty, Romy Ellis‐Doyle, Sonia Gandhi, Joel Handley, Edwin Jabbari, Keith Martin, Kevin McFarthing, Georgia Mills, Heather Mortiboys, Stephen Mullin, Rebecca Petty, Esther Sammler, Paula Scurfield, Simon R.W. Stott, George K. Tofaris, Li Wei, Caroline H. Williams‐Gray, Alan Wong, Marie‐Louise Zeissler, Richard K. Wyse, Camille B. Carroll, Thomas Foltynie, Oliver Bandmann, Anthony H.V. Schapira, on behalf of the EJS ACT‐PD Consortium   +29 more
wiley   +1 more source

Antihypertensive drug therapy prevents cerebral microvascular abnormalities in hypertensive rats. [PDF]

, 1987
S. L. Harper
openalex   +1 more source

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications

Medicinal Research Reviews, EarlyView.
ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra, Zoltán Mucsi, Janez Ilaš, Petra Dunkel   +3 more
wiley   +1 more source

Trends in antihypertensive drug utilization in British Columbia, 2004-2019: a descriptive study. [PDF]

CMAJ Open, 2023
Kim JD, Fisher A, Dormuth CR.
europepmc   +1 more source

New centrally acting antihypertensive drugs related to methyldopa and clonidine. [PDF]

, 1984
Charles S. Sweet
openalex   +1 more source

Progress in Molecular Imprinting—From Inhibition of Enzymatic Activity to Regulation of Cellular Pathways

Medicinal Research Reviews, EarlyView.
ABSTRACT Molecular imprinting is a very powerful tool in life science. The research areas benefiting from a wide range of capabilities of molecularly imprinted polymeric nanoparticles (nanoMIPs) include sample preparation, extraction, sensing/detection, diagnostics, and drug delivery.
Milada Vodova, Jaroslava Bezdekova, Marketa Vaculovicova   +2 more
wiley   +1 more source

The antihypertensive effect of propranolol : an animal study into the mechanisms through which beta-adrenoceptor blocking drugs lower blood pressure [PDF]

, 1980
Jos F.M. Smits
openalex   +1 more source

Mediterranean Diet Modulates Gene Expression of Cholesterol Efflux Receptors in High‐Risk Cardiovascular Patients

Molecular Nutrition &Food Research, EarlyView.
The graphical abstract (GA) displays the study of two randomized trials studying the molecular mechanisms of cholesterol efflux‐related genes analyzed via transcriptomics after two Mediterranean diet interventions. Cholesterol efflux molecules include ATP‐binding cassette transporters ABCA1 and ABCG1 in cholesterol transport to HDL. It also depicts the
Javier Hernando‐Redondo, Álvaro Hernáez, Albert Sanllorente, Xavier Pintó, Ramón Estruch, Jordi Salas‐Salvadó, Dolores Corella, Fernando Arós, Miguel Ángel Martínez‐González, Isaac Subirana, Daniel Muñoz‐Aguayo, Mireia Malcampo, Lluis Serra‐Majem, Dora Romaguera, Jose Lapetra, Emilio Ros, Francisco Tinahones, Rosa Maria Lamuela‐Raventós, Enrique Gómez‐Gracia, Montserrat Fitó, Olga Castañer   +20 more
wiley   +1 more source

THE EFFICACY OF NITROPRUSSIDE AND NITROGLYCERIN IN THE PRESENCE OF MINOXIDIL (LONITEN®), A NEW ANTIHYPERTENSIVE DRUG [PDF]

, 1980
Silas N. Glisson, W. Kwaczeniuk, B. C. Bloor   +2 more
openalex   +1 more source

Yerba Mate (Ilex paraguariensis St. Hill.) Tea May Have Cardiometabolic Beneficial Effects in Healthy and At‐Risk Subjects: A Randomized, Controlled, Blind, Crossover Trial in Nonhabitual Consumers

Molecular Nutrition &Food Research, EarlyView.
Yerba mate intake shows cardiometabolic beneficial effects decreasing blood pressure, blood lipids, inflammatory biomarkers and body fat in healthy and hypercholesterolemic non‐habitual consumers. ABSTRACT Yerba mate has been reported to have antihypertensive, hypocholesterolemic, antidiabetic, or antiobesity properties.
Laura Bravo, Sara Martínez‐López, Jose Luis Sierra‐Cinos, Raquel Mateos, Beatriz Sarriá   +4 more
wiley   +1 more source