Results 251 to 260 of about 139,220 (339)

Dauricine Overcomes Osimertinib Resistance in Lung Cancer by Inducing Ferroptosis via Stabilizing SAT1

Cancer Science, EarlyView.
Our study explores the potential of dauricine, a bioactive compound from Menispermum dauricum, to overcome osimertinib resistance in lung cancer. We demonstrate that dauricine, when combined with osimertinib, induces ferroptosis in resistant lung cancer cells by stabilizing SAT1, a key enzyme in oxidative stress regulation.
Biying Men, Zhijie Chen, Haotian Ge, Zhuoying Yang, Liang Yun, Jianjun Jiang, Meijuan Dian, Yujing He, Zehao Zhou, Ruihao Zhang, Tianbao Yan, Zichao Li, Yingxin Zhang, Yongjie He, Junming He, Xuguang Rao, Shuan Rao   +16 more
wiley   +1 more source

Antihypertensive drug-associated adverse events in osteoarthritis: a study of a large real-world sample based on the FAERS database. [PDF]

Front Pharmacol
Guo Z, Di J, Zhang Z, Chen S, Mao X, Wang Z, Yan Z, Li X, Tian Z, Mu C, Xiang C, Xiang C.   +11 more
europepmc   +1 more source

Continuous optical resolution of antihypertensive drug by column chromatography.

, 1997
Tatsuro Morino, Takanori Yamamoto
openalex   +2 more sources

Clinical Significance of Skeletal Fat‐to‐Muscle Ratio in Idiopathic Hyperaldosteronism

Clinical Endocrinology, EarlyView.
ABSTRACT Objective The objective of this study is to evaluate the correlation between the fat‐to‐muscle ratio (FMR) and insulin resistance (IR) with aldosterone production among patients with idiopathic hyperaldosteronism (IHA). Methods Patients with primary aldosteronism were screened from those with secondary hypertension and then subtyped via ...
Yuhe Jiang, Dan Li, Cassie Chen Cao, Wenjing Feng, Ruidong Liu, Yinfei Xu, Caixia Cao   +6 more
wiley   +1 more source

Genetically determined blood pressure, antihypertensive drug classes, and frailty: A Mendelian randomization study. [PDF]

Aging Cell
Zhuang Z, Li Y, Zhao Y, Huang N, Wang W, Xiao W, Du J, Dong X, Song Z, Jia J, Liu Z, Clarke R, Qi L, Huang T.   +13 more
europepmc   +1 more source

MYOCARDIAL INFARCTION AND ANTIHYPERTENSIVE DRUG THERAPY [PDF]

, 1996
Michel E. Safar
openalex   +1 more source

Effect of interdisciplinary obesity care on metabolic markers and body weight in people with type 2 diabetes in a rural setting: A randomised controlled trial

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Management of type 2 diabetes includes medications that can unintentionally increase obesity and insulin resistance. This unblinded, single‐centre, randomised controlled trial focused on rural Australian adults with type 2 diabetes (aged 18–75 and body mass index [BMI] >30 kg/m2), measuring the effectiveness of a tailored interdisciplinary ...
Giuliana O. Murfet, Iain K. Robertson, Sharon P. Luccisano, Michelle L. Kilpatrick   +3 more
wiley   +1 more source

Antihypertensive drugs and anæsthesia [PDF]

Anaesthesia, 1966
openaire   +3 more sources

A Safe and Efficient 7‐Week Immunotherapy Protocol With Aluminum Hydroxide Adsorbed Bee Venom

Allergy, EarlyView.
Lisa Arzt‐Gradwohl, Urban Čerpes, Eva Schadelbauer, Clemes Schöffl, Sereina Annik Herzog, Christoph Schrautzer, Danijela Bokanovic, Lukas Koch, Karin Laipold, Barbara Binder, Gunter Sturm   +10 more
wiley   +1 more source

Effect of glucagon‐like peptide 1 receptor agonists on systolic blood pressure in patients with obesity, with or without diabetes: A systematic review and network meta‐analysis

Clinical Obesity, EarlyView.
Summary The effect of glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) on systolic blood pressure (SBP) in patients with obesity with or without diabetes remains unclear. The aim was to compare the effect of different drug–dose combinations of GLP‐1RAs on SBP.
Abraish Ali, Asad Ali Siddiqui, Muhammad Shariq Usman, Izza Shahid, Muhammad Shahzeb Khan, Prinka Perswani   +5 more
wiley   +1 more source