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Drug Interactions with Antihypertensive Drugs

Drugs, 1978
Drug interactions with antihypertensive drugs can be either beneficial or hazardous. The hazardous interactions are relatively infrequent but must be shown so they can be avoided. Those of most importance involve interaction with guanethidine-type agents and tricyclic antidepressants, amphetamine-type anorexiants or phenolpropanolamine-type common cold
J E, Crook, A S, Nies
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Antihypertensive drugs and the kidney

Current Cardiology Reports, 2004
In the United States, 50 million Americans are estimated to have hypertension. Over the past several decades, it has become clear that hypertension is both a cause and a consequence of kidney disease. In contrast to the striking decline in mortality rates from both stroke and coronary heart disease, the prevalence of hypertension as a cause of end ...
Mitra K, Nadim   +2 more
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Drug Interactions with Antihypertensives

Current Hypertension Reports, 2021
Hypertension is remarkably prevalent, affecting an estimated 1.13 billion people worldwide. It often requires the use of multi-drug regimens and is commonly associated with a myriad of other comorbidities which increase medication use. The pervasive use of antihypertensive medications combined with the presence of polypharmacy in many hypertensive ...
Michelle A, Fravel, Michael, Ernst
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Antihypertensive drugs and the heart

Current Cardiology Reports, 2004
The main goal of current antihypertensive therapy is to achieve a lowering of intra-arterial pressure by various mechanisms. A plethora of data suggests that this reduces cardiovascular morbidity and mortality due to stroke, heart failure and to a lesser extent, ischemic heart disease.
Joseph A, Diamond, Robert A, Phillips
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Antihypertensive drugs

Clinical Pharmacology & Therapeutics, 1962
Drug therapy for essential hypertension is now firmly established. Agents presently available, if used wisely, are capable of controlling hypertension in almost every patient requiring such treatment. There are certain important factors which must be carefully evaluated before patients are started on long‐term antihypertensive therapy.
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Antihypertensive Drugs in Pregnancy

Clinics in Perinatology, 1985
When mean arterial pressure exceeds 140 mmHg (equivalent to 180/120), there is a significant risk of maternal cerebral vascular damage. Therefore it is recommended that blood pressures greater than 170/110 should be treated with urgency, aiming to maintain the blood pressure at all times at less than 170/110 but not lower than 130/90.
R P, Naden, C W, Redman
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Antihypertensive Drugs

American Journal of Cardiovascular Drugs, 2002
For most patients with systemic hypertension, long-term drug treatment is indicated and is beneficial. There is overwhelming evidence to suggest that antihypertensive drugs offer protection against complications of hypertension. Whereas nondrug therapeutic options should be implemented in all patients, a vast majority will require pharmacological ...
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EFFICACY OF ANTIHYPERTENSIVE DRUGS

The Lancet, 1976
The magnitude of the fall in blood-pressure in response to an antihypertensive drug depends on the level of the pretreatment pressure, and there is a direct relationship between the two in that the higher the pretreatment pressure the greater the fall in pressure in response to treatment.
G T, Dixon, E S, Johnson
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ICP and Antihypertensive Drugs

2018
Arterial hypertension is among the leading risks for mortality. This burden requires in hypertensive patients the use of single, double or more antihypertensive drugs. The relationship between intracranial pressure (ICP) and arterial blood pressure is complex and still under debate. The impact of antihypertensive drugs on ICP is unknown.
Charlotte, Rouzaud-Laborde   +4 more
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Antihypertensive Drugs in Pregnancy

Seminars in Nephrology, 2011
Blood pressure targets and medications that are safe differ in pregnant women compared with nonpregnant individuals. The principles of treatment for mild, moderate, and severe hypertension in pregnancy, chronic versus gestational versus preeclampsia, and women hypertensive at term versus remote from term are reviewed.
Tiina, Podymow, Phyllis, August
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