Results 71 to 80 of about 150,610 (217)

Pharmacogenomics of Hypertension and Preeclampsia: Focus on Gene–Gene Interactions

open access: yesFrontiers in Pharmacology, 2018
Hypertension is a leading cause of cardiovascular mortality, but only about half of patients on antihypertensive therapy achieve blood pressure control.
Marcelo R. Luizon   +3 more
doaj   +1 more source

Olmesartan-based monotherapy vs combination therapy in hypertension: A meta-analysis based on age and chronic kidney disease status. [PDF]

open access: yes, 2017
Antihypertensive monotherapy is often insufficient to control blood pressure (BP). Several recent guidelines advocate for initial combination drug therapy in many patients. This meta-analysis of seven randomized, double-blind studies (N = 5888) evaluated
Bakris, George   +3 more
core   +1 more source

Prevalence and impact of prescribing cascades in community‐dwelling adults: Longitudinal analysis of the Irish longitudinal study on ageing (TILDA)

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Prescribing cascades occur when medication is prescribed to prevent/treat the adverse effects of another medication and may be intentional/unintentional. This study examines the prevalence of nine prescribing cascades (ThinkCascades) in The Irish Longitudinal StuDy on Ageing (TILDA).
Ann Sinéad Doherty   +7 more
wiley   +1 more source

Effects of candesartan, an angiotensin II receptor type I blocker, on atrial remodeling in spontaneously hypertensive rats [PDF]

open access: yes, 2015
Hypertension-induced structural remodeling of the left atrium (LA) has been suggested to involve the renin–angiotensin system. This study investigated whether treatment with an angiotensin receptor blocker, candesartan, regresses atrial remodeling in ...
Choisy, Stéphanie C.   +5 more
core   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra   +8 more
wiley   +1 more source

Cutaneous reactions due to antihypertensive drugs

open access: yesIndian Journal of Dermatology, 2006
Out of a total of 1147 patients on antihypertensive drugs, 23 (2.04%) developed adverse cutaneous drug reactions (ACDR). The commonest antihypertensive drug group causing ACDR was beta-blockers of which atenolol was the commonest culprit.
Upadhayai J   +5 more
doaj  

Effect of ACE Inhibitors, ARBs, and Other Antihypertensive Drugs on Hypertensive Patients with COVID-19 Infection

open access: yesNovelty in Biomedicine
Background: To investigate differences in disease severity and outcomes among COVID-19 patients with a history of hypertension using angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and other antihypertensive drugs.
Seyedpouzhia Shojaei   +7 more
doaj   +1 more source

Choosing antihypertensive treatment for a South African population

open access: yesSouth African Family Practice, 2007
There is no uniform agreement as to which antihypertensive drugs should be given for initial therapy. All of the antihypertensive agents are roughly equally effective, producing a good antihypertensive response in 30 to 50 percent of cases.
M.T. Mpe
doaj   +1 more source

Antihypertensive treatment for hypertensive patients with heart failure using real-world Japanese data: subanalysis of the Retrospective study of antihypertensives for lowering blood pressure (REAL) study

open access: yesClinical and Experimental Hypertension, 2020
The number of patients with heart failure (HF) is rapidly increasing. Although hypertension is related to onset of HF, antihypertensive treatment status for these patients has not been fully examined.
Mitsuru Ohishi   +4 more
doaj   +1 more source

Psychometric properties of the Polish version of the eight-item Morisky Medication Adherence Scale in hypertensive adults. [PDF]

open access: yes, 2016
Low adherence to pharmacological treatment is often associated with poor blood pressure control, but identification of nonadherent patients in outpatient settings is difficult.
Chudiak, Anna   +5 more
core   +1 more source

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