Results 81 to 90 of about 139,220 (339)

Antihypertensive drug therapy [PDF]

open access: yesAnnals of Translational Medicine, 2018
Lifestyle measures plus antihypertensive drug therapy should be used to treat adults with hypertension (1-4). Adults with clinical cardiovascular disease (coronary heart disease, heart failure, and stroke) should have their blood pressure reduced below 130/80 mmHg for secondary prevention of recurrent cardiovascular disease events (4).
openaire   +3 more sources

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima   +11 more
wiley   +1 more source

Cutaneous reactions due to antihypertensive drugs

open access: yesIndian Journal of Dermatology, 2006
Out of a total of 1147 patients on antihypertensive drugs, 23 (2.04%) developed adverse cutaneous drug reactions (ACDR). The commonest antihypertensive drug group causing ACDR was beta-blockers of which atenolol was the commonest culprit.
Upadhayai J   +5 more
doaj  

The Combination of Beta Blockers and Renin-Angiotensin System Blockers Improves Survival in Incident Hemodialysis Patients: A Propensity-Matched Study

open access: yesKidney International Reports, 2017
Although several studies suggest that the prognosis of hypertensive dialysis patients can be improved by using antihypertensive drug therapy, it is unknown whether the prescription of a particular class or combination of antihypertensive drugs is ...
José Luño   +22 more
doaj   +1 more source

Antihypertensive treatment for hypertensive patients with heart failure using real-world Japanese data: subanalysis of the Retrospective study of antihypertensives for lowering blood pressure (REAL) study

open access: yesClinical and Experimental Hypertension, 2020
The number of patients with heart failure (HF) is rapidly increasing. Although hypertension is related to onset of HF, antihypertensive treatment status for these patients has not been fully examined.
Mitsuru Ohishi   +4 more
doaj   +1 more source

Therapeutic efficacy and safety of ACE inhibitors in the hypertensive paediatric population: a review [PDF]

open access: yes, 2016
Purpose: Since 1997, strong incentives have been introduced worldwide to improve access to safe and effective medicines addressing the therapeutic needs of children. ACE inhibitors, the most prescribed antihypertensive drugs in the paediatric population,
De Bruyne, Pauline   +2 more
core   +3 more sources

Individualization of Antihypertensive Drug Treatment [PDF]

open access: yesDiabetes Care, 2013
Antihypertensive drug classes are usually classified as 1st, 2nd, 3rd, and 4th or 5th choice to help physicians select the drug most suitable for treatment initiation among the very many classes available to lower blood pressure (BP) in patients with a BP elevation.
Mancia, G, Grassi, G
openaire   +3 more sources

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu   +21 more
wiley   +1 more source

Repurposing antihypertensive drugs for pain disorders: a drug-target mendelian randomization study

open access: yesFrontiers in Pharmacology
ObjectiveAddressing the rising prevalence of pain disorders and limitations of current analgesics, our study explores repurposing antihypertensive drugs for pain management, inspired by the link between hypertension and pain.
Kai Du   +4 more
doaj   +1 more source

Comprehensive Qualitative Drug Screening in Emergency Toxicology Using an Automated LC–MSn System:Simultaneous Quantification of Relevant Drugs and Metabolites in Blood Plasma

open access: yesDrug Testing and Analysis, EarlyView.
Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer   +4 more
wiley   +1 more source

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