Results 271 to 280 of about 157,060 (341)

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

Experimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu, Xingyu Qiu, Nan Xu, Gensheng Zhang, Enyin Lai, Liang Zhao   +5 more
wiley   +1 more source

Enteropathy and intestinal malabsorption in patients treated with antihypertensive drugs. A retrospective cohort study. [PDF]

Saudi Med J
Lee SR, Lee EG, Cho YH, Park EJ, Lee YI, Choi JI, Kwon RJ, Son SM, Lee SY, Yi YH, Kim GL, Kim YJ, Lee JG, Tak YJ, Lee SH, Ra YJ.   +15 more
europepmc   +1 more source

Diltiazem-loaded cubosomes: a novel drug delivery for improved bioavailability and enhanced antihypertensive action

Shaik Muhammed Athar, Dr. B. Narasimha Rao, S. Nashrah Nasreen   +2 more
openalex   +1 more source

Persistence of fatigue in the absence of pathophysiological mechanisms in some patients more than 2 years after the original SARS‐CoV‐2 infection

Experimental Physiology, EarlyView.
Abstract Following an acute infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), a substantial percentage of patients report the persistence of debilitating symptoms, often grouped in a syndrome termed ‘long COVID’. We sought to identify potential pathophysiological mechanisms responsible for the persistence, in some long COVID ...
Giovanni Baldassarre, Lucrezia Zuccarelli, Thomas Favaretto, Caterina Ursella, Andrea Palomba, Paulo Cesar do Nascimento Salvador, Emanuela Sozio, Ernesto Crisafulli, Massimo Imazio, Carlo Tascini, Bruno Grassi   +10 more
wiley   +1 more source

Long-term exposure to antihypertensive drugs and the risk of cancer occurrence: evidence from a large population-based study. [PDF]

J Hypertens
Franchi M, Torrigiani G, Kjeldsen SE, Mancia G, Corrao G.   +4 more
europepmc   +1 more source

Exploring the nexus: Clinical and physiological correlation between cardiovascular disease and colorectal cancer

Experimental Physiology, EarlyView.
Abstract Colorectal cancer (CRC) and cardiovascular disease (CVD) are leading causes of morbidity and mortality worldwide, traditionally studied as distinct pathologies. However, emerging evidence suggests a significant physiological and molecular overlap between these conditions, indicating that they might share common pathophysiological pathways. The
Mohamad Bashir, Ali Murtada, Matti Jubouri, Wael Awad, Ian Williams, Damian M. Bailey   +5 more
wiley   +1 more source

Health Policy Newsletter March 2007 Vol. 20, No. 1 [PDF]

, 2008

core   +1 more source

Evidence of racial differences in peripheral blood pressure, central haemodynamics and arterial stiffness between young Black and White women

Experimental Physiology, EarlyView.
Abstract Hypertension diagnosed via peripheral (brachial) blood pressure (pBP) is a strong independent predictor of overt cardiovascular disease (CVD). However, central (aortic) blood pressure (cBP), which is influenced by arterial stiffness, may be more strongly associated with CVD risk. Young Black women (BLW) demonstrate higher pBP than White women (
Michele N. D'Agata, Elissa K. Hoopes, Alexs A. Matias, Mackenzie L. Rattigan, Freda Patterson, Melissa A. Witman   +5 more
wiley   +1 more source

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

Experimental Physiology, EarlyView.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó, Luis Eduardo M. Quintas   +1 more
wiley   +1 more source