Results 261 to 270 of about 54,267 (309)
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Journal of the American Academy of Dermatology, 1981
The antimalarials, chloroquine, hydroxychloroquine, and quinacrine, are used primarily for malaria; but they can be beneficial for cutaneous lupus erythematosus (LE), polymorphous light eruption, solar urticaria, and porphyria cutanea tarda. Antimalarials bind to deoxyribonucleic acid (DNA) which prevents DNA and ribonucleic acid (RNA) polymerase ...
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The antimalarials, chloroquine, hydroxychloroquine, and quinacrine, are used primarily for malaria; but they can be beneficial for cutaneous lupus erythematosus (LE), polymorphous light eruption, solar urticaria, and porphyria cutanea tarda. Antimalarials bind to deoxyribonucleic acid (DNA) which prevents DNA and ribonucleic acid (RNA) polymerase ...
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Drug Discovery Today, 2005
Analysis of the trends in antimalarial research depicts a slow growth in launched products since 1995. However, 2002 saw the completion, after ten years, of the malarial genome project and an upsurge in products entering active development can be seen at the end of this period.
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Analysis of the trends in antimalarial research depicts a slow growth in launched products since 1995. However, 2002 saw the completion, after ten years, of the malarial genome project and an upsurge in products entering active development can be seen at the end of this period.
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Current Opinion in Pharmacology, 2018
Over the past decade, new high-throughput phenotypic assays with malaria parasites have been developed, and these were used to screen millions of compounds. This effort, as well as improving older chemical scaffolds and optimising compounds against both known and new drug targets has resulted in the discovery of exciting new pipeline drug candidates ...
Rob, Hooft van Huijsduijnen +1 more
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Over the past decade, new high-throughput phenotypic assays with malaria parasites have been developed, and these were used to screen millions of compounds. This effort, as well as improving older chemical scaffolds and optimising compounds against both known and new drug targets has resulted in the discovery of exciting new pipeline drug candidates ...
Rob, Hooft van Huijsduijnen +1 more
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[Antimalarial drug resistance].
Medecine et maladies infectieuses, 2006Drug resistant malaria is mostly due to Plasmodium falciparum, the highly prevalent species in tropical Africa, Amazon, and Southeast Asia. P. falciparum is responsible for severe involvement of fever or anemia causing more than a million deaths per year.
Le Bras, J., Musset, L., Clain, J.
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Diaminoquinoline antimalarials
Journal of Medicinal Chemistry, 1969N D, Heindel +5 more
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Misconceptions About Antimalarials
International Journal of Dermatology, 1989Article evoquant succintement les conceptions erronees concernant la toxicite oculaire des ...
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