Results 301 to 310 of about 92,770 (362)

Stereospecific Resistance to N2-Acyl Tetrahydro-β-carboline Antimalarials Is Mediated by a PfMDR1 Mutation That Confers Collateral Drug Sensitivity. [PDF]

ACS Infect Dis
Bremers EK, Butler JH, Do Amaral LS, Merino EF, Almolhim H, Zhou B, Baptista RP, Totrov M, Carlier PR, Cassera MB.   +9 more
europepmc   +1 more source

Unlocking chemical markers for the standardization of antimalarial medicinal plants and products: Application of the herbal marker ranking system (Herb MaRS)

John Nii Addotey, Priscilla Boadu, Emmanuel Quaye Kontoh, Flavia Owusu Yeboah, F. Kaiser, Francis Ackah Armah, Rita A. Dickson, Isaac Kingsley Amponsah   +7 more
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The Development Process for Discovery and Clinical Advancement of Modern Antimalarials

Journal of Medicinal Chemistry, 2019
Malaria is a devastating disease caused by Plasmodium parasites resulting in approximately 435,000 deaths in 2018. The impact of malaria is compounded by the emergence of widespread resistance to current antimalarial therapies.
Trent Ashton, Shane M Devine, Jörg J Möhrle   +2 more
exaly   +2 more sources

Glucocorticoids and antimalarials in systemic lupus erythematosus: an update and future directions

Current Opinion in Rheumatology, 2018
Purpose of review The purpose of this review is highlighting the most recent evidence on the clinical efficacy and toxicity of glucocorticoids and antimalarials in systemic lupus erythematosus (SLE) and provide recommendations on their current use ...
Guillermo Ruiz-Irastorza
exaly   +2 more sources

Efficacy and comparison of antimalarials in cutaneous lupus erythematosus subtypes: a systematic review and meta-analysis

British Journal of Dermatology, 2017
F. Chasset, J. Bouaziz, N. Costedoat-Chalumeau, C. Francès, L. Arnaud   +4 more
exaly   +2 more sources

Pyrimidine-based antimalarials: design strategies and antiplasmodial effects

MedChemComm, 2016
Kamaljit Singh
exaly   +2 more sources

To consider or not antimalarials as a prophylactic intervention in the SARS-CoV-2 (COVID-19) pandemic

Annals of the Rheumatic Diseases, 2020
I read with great interest the letter by Spinelli et al published in the Annals of the Rheumatic Diseases .1 The authors describe the existing scientific evidence concerning the potential antiviral activity of chloroquine and hydroxychloroquine (HCQ ...
K. Parperis
semanticscholar   +1 more source

Update on antimalarials and systemic lupus erythematosus

Current Opinion in Rheumatology, 2020
Purpose of review The purpose of this review is highlighting the most recent evidence on the clinical efficacy and toxicity of antimalarials in systemic lupus erythematosus (SLE).
G. Ruiz‐Irastorza, D. Martín-Iglesias, A. Soto-Peleteiro   +2 more
semanticscholar   +1 more source

An Overview of Available Antimalarials: Discovery, Mode of Action and Drug Resistance.

Current molecular medicine, 2020
Malaria is one of the three most deadly infectious diseases in the world and seriously endangers human health and life. To reduce the public health burden of this disease, scientists have focused on the discovery and development of effective antimalarial
Yu-Qing Tang, Q. Ye, He Huang, Weiyi Zheng   +3 more
semanticscholar   +1 more source