Results 301 to 310 of about 90,085 (338)
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Journal of the American Academy of Dermatology, 1981
The antimalarials, chloroquine, hydroxychloroquine, and quinacrine, are used primarily for malaria; but they can be beneficial for cutaneous lupus erythematosus (LE), polymorphous light eruption, solar urticaria, and porphyria cutanea tarda. Antimalarials bind to deoxyribonucleic acid (DNA) which prevents DNA and ribonucleic acid (RNA) polymerase ...
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The antimalarials, chloroquine, hydroxychloroquine, and quinacrine, are used primarily for malaria; but they can be beneficial for cutaneous lupus erythematosus (LE), polymorphous light eruption, solar urticaria, and porphyria cutanea tarda. Antimalarials bind to deoxyribonucleic acid (DNA) which prevents DNA and ribonucleic acid (RNA) polymerase ...
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The Lancet, 2004
Multidrug resistance has rendered monotherapy for malaria useless in most parts of the world, and has also compromised the usefulness of many of the available combination chemotherapies. New antimalarial regimens are, therefore, urgently needed. We review the various antimalarial combinations that can be used to treat otherwise drug-resistant disease ...
Peter Gottfried, Kremsner +1 more
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Multidrug resistance has rendered monotherapy for malaria useless in most parts of the world, and has also compromised the usefulness of many of the available combination chemotherapies. New antimalarial regimens are, therefore, urgently needed. We review the various antimalarial combinations that can be used to treat otherwise drug-resistant disease ...
Peter Gottfried, Kremsner +1 more
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Lupus, 1996
In the city of Lima, capital of Peru, the wife of the Viceroy, at that time the Count of Cinchon fell sick... Her illness was tertian fever... The rumour of her illness... became known by the people in the city, spread to neighboring places and reached Loxa. I believe since then thirty or forty years have passed.
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In the city of Lima, capital of Peru, the wife of the Viceroy, at that time the Count of Cinchon fell sick... Her illness was tertian fever... The rumour of her illness... became known by the people in the city, spread to neighboring places and reached Loxa. I believe since then thirty or forty years have passed.
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An Overview of Currently Available Antimalarials.
Current Topics in Medicinal Chemistry, 2017BACKGROUND Despite the substantial progress over the time, malaria remains a major public health concern and causing hundreds of thousands of deaths.
N. Gorobets +4 more
semanticscholar +1 more source
Angewandte Chemie International Edition, 2003 AbstractApproximately 40 % of the world population live in areas with the risk of malaria. Each year, 300–500 million people suffer from acute malaria, and 0.5–2.5 million die from the disease. Although malaria has been widely eradicated in many parts of the world, the global number of cases continues to rise.
Jochen Wiesner +3 more
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Pyrimidine-based antimalarials: design strategies and antiplasmodial effects
, 2016Pyrimidine-containing compounds have attracted great attention because of their biological effects, therapeutic potential and flexibility in structural modification by way of diversifying various positions as well as heterocyclic ring transformations ...
Kamaljit Singh, T. Kaur
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2013
Hydroxychloroquine and chloroquine are antimalarial drugs used in the treatment of rheumatoid arthritis, systemic lupus erythematosus (SLE), antiphospholipid syndrome, skin diseases, and in the treatment of chronic Q fever. Hydroxychloroquine is the more widely used.
Pile, Kevin (R17082) +3 more
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Hydroxychloroquine and chloroquine are antimalarial drugs used in the treatment of rheumatoid arthritis, systemic lupus erythematosus (SLE), antiphospholipid syndrome, skin diseases, and in the treatment of chronic Q fever. Hydroxychloroquine is the more widely used.
Pile, Kevin (R17082) +3 more
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Antimalarials in rheumatic diseases
Baillière's Clinical Rheumatology, 1990The antimalarials hydroxychloroquine and chloroquine remain established and effective agents for the treatment of rheumatoid arthritis and systemic lupus erythematosus. Although the mechanisms of action remain uncertain, evidence is accumulating that the antirheumatic and immunological effects of the antimalarials are related to their massive ...
Tett, S, Cutler, D, Day, R
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Traditional antimalarials and the development of novel antimalarial drugs
Journal of Ethnopharmacology, 2005Malaria continues to be a major cause of mortality and morbidity especially throughout the developing world. In the last 25 years or so a number of significant advances have been made that have the potential to make a major contribution to the control of this disease.
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, 2016
The currently used antimalarials suffer from drug resistance which is hampering the global management of malaria infection. To overcome drug resistance, they are administered as combination therapies which involve combination of two or more antimalarials.
B. Aderibigbe, Z. Mhlwatika
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The currently used antimalarials suffer from drug resistance which is hampering the global management of malaria infection. To overcome drug resistance, they are administered as combination therapies which involve combination of two or more antimalarials.
B. Aderibigbe, Z. Mhlwatika
semanticscholar +1 more source