A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann +7 more
wiley +1 more source
Investigation of fungal nosocomial infections and antimicrobial drug resistance pattern after open-heart surgery; a cross-sectional study. [PDF]
Lashkarbolouk N +3 more
europepmc +1 more source
Boston: mechanisms of antimicrobial drug resistance [PDF]
openaire +2 more sources
The Janus nanomotors leverage an “asymmetric structure‐driven functional synergy” strategy to orchestrate spatiotemporally coordinated catalytic functions, in situ self‐amplifying NO generation, and deep tumor penetration, thereby enabling controllable, sustained, and uniform NO generation within the tumor microenvironment.
Chengcheng Li +6 more
wiley +1 more source
Editorial: Systems biology and antimicrobial drug resistance. [PDF]
Soni V, Sharma AK, Dubey N, Mishra S.
europepmc +1 more source
STING/Type I Interferon Pathway Activation Confers Multimodal Therapeutic Benefits in Osteomyelitis
STING/type I interferon signaling counteracts osteomyelitis through coordinated control of pain, bone destruction, and abscess formation. It inhibits pathogen‐induced nociceptor activation, restrains osteoclast‐mediated bone resorption, and suppresses IL‐1β‐driven neutrophil recruitment.
Yang Chen +19 more
wiley +1 more source
Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He +7 more
wiley +1 more source
Correction: A systematic review and meta-analysis of antimicrobial resistance knowledge, attitudes, and practices: Current evidence to build a strong national antimicrobial drug resistance narrative in Ethiopia. [PDF]
Woldegeorgis BZ +3 more
europepmc +1 more source
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu +10 more
wiley +1 more source
Initiatives for addressing antimicrobial resistance in the environment : executive summary [PDF]
This executive summary highlights key themes from a scientific white paper and discussion at the International Environmental Antimicrobial Resistance (AMR) Forum, a meeting hosted by the U.S. Centers for Disease Control and Prevention, the U.K.
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