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Antimicrobial peptides

Journal of the American Academy of Dermatology, 2005
Antimicrobial peptides (AMPs) are small molecular weight proteins with broad spectrum antimicrobial activity against bacteria, viruses, and fungi. These evolutionarily conserved peptides are usually positively charged and have both a hydrophobic and hydrophilic side that enables the molecule to be soluble in aqueous environments yet also enter lipid ...
Arash, Izadpanah, Richard L, Gallo
openaire   +2 more sources

Antimicrobial Peptides

Surgical Infections, 2018
Abstract Background: Bacterial resistance to available antibiotics has resulted in enhanced efforts at antibiotic stewardship but also has led to investigation into alternative methods for managing surgical infections.
openaire   +2 more sources

Unifying the classification of antimicrobial peptides in the antimicrobial peptide database

2022
Natural products offer an important avenue to novel therapeutics against drug-resistant bacteria, viruses, fungi, parasites, and cancer. However, there are numerous hurdles and challenges in discovering such molecules, including antimicrobial peptides (AMPs).
openaire   +2 more sources

Branched antimicrobial peptides

Russian Journal of Bioorganic Chemistry, 2007
Branched peptides E(RLAR)2, E[E(RLAR)2]2, E(KLAR)2, and E[E(KLAR)2]2 were synthesized on the basis of tetrapeptides RLAR and KLAR and glutamic acid bis(pentafluorophenyl) ester. Their minimal antimicrobial concentrations were shown to decrease along with increase in branching, achieving 12 microM for Escherichia coli cells, which is comparable to ...
A Iu, Khrushchev   +3 more
openaire   +2 more sources

Antimicrobial peptides of leukocytes

Current Opinion in Hematology, 1997
Leukocytes use an array of antimicrobial peptides and proteins to help them destroy invading microorganisms. These endogenous antibiotic molecules are remarkable for their structural variety, rapid evolutionary divergence, intraspecies variation, and complex yet subtle interactions with their targets.
T, Ganz, R I, Lehrer
openaire   +2 more sources

Antimicrobial peptides towards clinical application: Delivery and formulation

Advanced Drug Delivery Reviews, 2021
Cheng Wang, Jiang Xia, Tingting Hong
exaly  

Mechanism of Antimicrobial Peptides: Antimicrobial, Anti-Inflammatory and Antibiofilm Activities

International Journal of Molecular Sciences, 2021
Yuzhu Song, Ying Luo
exaly  

Inoculum effect of antimicrobial peptides

Proceedings of the National Academy of Sciences of the United States of America, 2021
Maria Rosa Loffredo   +2 more
exaly  

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