Results 61 to 70 of about 45,464 (241)

Facially amphiphilic polyionene biocidal polymers derived from lithocholic acid

Bioactive Materials, 2018
Bacterial infections have become a global issue that requires urgent attention, particularly regarding to emergence of multidrug resistant bacteria. We developed quaternary amine-containing antimicrobial poly(bile acid)s that contain a hydrophobic core ...
Mitra S. Ganewatta, Md Anisur Rahman, Louis Mercado, Tinom Shokfai, Alan W. Decho, Theresa M. Reineke, Chuanbing Tang   +6 more
doaj   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Synthesis and characterization of glyoxal-crosslinked chitosan with N-amino anthracene succinimide polymers for antimicrobial applications

BMC Chemistry
This paper presents the synthesis and characterization of a novel chitosan-derivative polymers by using glyoxal as acrosslinker between chitosan and N-amino-9,10-dihydro-anthracene-9,10-α,β-succinamide (AS) under our conditions.
Ahmed G. Taha, A. M. Hezma
doaj   +1 more source

Packed Hydrogel Microfibers as Scaffolds Supporting Dynamic Cellular Behavior and Biomaterial Inks in 3D Printing

Advanced Healthcare Materials, EarlyView.
Packed hydrogel microfiber (PHM) materials consist of flexible and high aspect ratio hydrogel components that, as a bulk material, are simultaneously mechanically robust and dynamic. Cells cultured in or on PHM scaffolds can be influenced by topographical cues or interact with a dynamic environment that permits cell spreading and multicellular ...
M. Gregory Grewal, Remington M. Martinez, Georgia T. Helein, Montserrath G. Ibarra Rivera, Rodolfo Martinez Jr., Jenna L. Sumey, Steven R. Caliari, Christopher B. Highley   +7 more
wiley   +1 more source

Sugars in Antimicrobial Polymers – The Impact of Sugar‐Lectin Binding in Membrane Interaction of Cationic Glycopolymers

Advanced Materials Interfaces
Membrane‐active antimicrobial polymers (APs) are promising alternatives for treating infectious diseases as they are less susceptible to antimicrobial resistance development. However, their non‐specific cytotoxicity limits their clinical application. One
Alain M. Bapolisi, Steffen Tank, Anne‐Catherine Lehnen, Antje Stindt, Rujuta Athavale, Jan A. M. Kurki, Sany Chea, Sophia Rosencrantz, Ruben R. Rosencrantz, Katja M. Arndt, Matthias Hartlieb   +10 more
doaj   +1 more source

Nature-inspired antimicrobial polymers--assessment of their potential for biomedical applications. [PDF]

PLoS ONE, 2013
We explored the potential of poly(oxonorbornene)-based synthetic mimics of antimicrobial peptides (SMAMPs), a promising new class of antimicrobial polymers with cell-selectivity and low resistance development potential, for clinical applications.
Ali Al-Ahmad, Dougal Laird, Peng Zou, Pascal Tomakidi, Thorsten Steinberg, Karen Lienkamp   +5 more
doaj   +1 more source

Photothermal‐Activated Antibacterial Amyloid‐Polyphenol‐Iron Hydrogels for Synergistic Wound Healing

Advanced Healthcare Materials, EarlyView.
We report a thermally triggered supramolecular hydrogel (LTFe) formed by Fe3+ and tannic acid on lysozyme amyloid fibrils. Fe3+ enables rapid gelation and photothermal transduction with an efficiency of 88.56%. The LTFe hydrogel exhibits excellent biocompatibility, potent antibacterial activity against E. coli and S.
Di Wu, Jiangtao Zhou, Yang Shen, Qiyao Sun, Tong Li, Xiaoyang Zou, Bin Liu, Hongshan Liang, Raffaele Mezzenga   +8 more
wiley   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Adsorbable and Antimicrobial Amphiphilic Block Copolymers with Enhanced Biocompatibility

Macromolecular Materials and Engineering
To minimize or avoid the use of antibiotics, antimicrobial polymers have emerged as a promising option to fight biomaterial‐associated infections, e.g., on titanium‐based implants.
Cornelia Wolf‐Brandstetter, Rafael Methling, Dirk Kuckling   +2 more
doaj   +1 more source

Development of Sustainable Antimicrobial Cellulose Additives for Melt Electrowritten PLA Fibers: From Synthesis to Extensional Rheology

Proceedings
Addressing the dual challenges of plastic sustainability and antibiotic resistance, this work develops cationic cellulose nanocrystals (CNCs) with potent inherent antimicrobial activity [...]
Rosa Barranco García, Mercedes Fernández San Martín, Coro Echeverria, Alexandra Muñoz-Bonilla, Marta Fernández-García   +4 more
doaj   +1 more source