Results 41 to 50 of about 81,960 (246)

Linezolid use in German acute care hospitals: results from two consecutive national point prevalence surveys

Antimicrobial Resistance and Infection Control, 2019
Background Linezolid belongs to a reserve group of antibiotics. In recent years, reports on linezolid resistance in gram-positive cocci have become more frequent. Overuse of linezolid is a relevant factor for resistance development. The objective of this
Tobias Siegfried Kramer, Frank Schwab, Michael Behnke, Sonja Hansen, Petra Gastmeier, Seven Johannes Sam Aghdassi   +5 more
doaj   +1 more source

Associations between antimicrobial resistance in fecal Escherichia coli isolates and antimicrobial use in Canadian turkey flocks

Frontiers in Microbiology, 2022
Antimicrobial resistance (AMR) in enteric bacteria continues to be detected in turkey flocks and retail products worldwide, including in Canada. However, studies assessing linkages between on-farm antimicrobial use (AMU) and the development of AMR are ...
Rima D. Shrestha, Agnes Agunos, Sheryl P. Gow, Anne E. Deckert, Csaba Varga, Csaba Varga   +5 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Capturing systematically users' experience of evaluation tools for integrated AMU and AMR surveillance

Frontiers in Veterinary Science, 2023
Tackling antimicrobial resistance (AMR) is a goal for many countries. Integrated surveillance of antimicrobial use (AMU) and resistance is a prerequisite for effective risk mitigation.
Lis Alban, Lis Alban, Marion Bordier, Marion Bordier, Marion Bordier, Barbara Häsler, Lucie Collineau, Laura Tomassone, Houda Bennani, Cécile Aenishaenslin, Madelaine Norström, Maurizio Aragrande, Maria Eleni Filippitzi, Maria Eleni Filippitzi, Pedro Moura, Marianne Sandberg   +15 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

National-Level Consumption of Antimicrobials in the Veterinary Sector in Uganda: A Report on Analysis of Import Data for 2021

Antibiotics
Background: Antimicrobials are crucial for animal health and food security. However, their overuse in animals can lead to the emergence of resistant microorganisms.
Marion Murungi, Patrick Vudriko, Helen Byomire Ndagije, Diana Nakitto Kesi, Allan Serwanga, Kalidi Rajab, Leonard Manirakiza, John Paul Waswa, Hassan Kasujja, Mark Barigye, Ddembe Kaweesi, Harriet Akello, Juliet Namugambe, Reuben Kiggundu, Niranjan Konduri   +14 more
doaj   +1 more source

Eight years of sales surveillance of antimicrobials for veterinary use in Germany-What are the perceptions?

PLoS ONE, 2020
A surveillance system for sales volumes of antimicrobial agents for veterinary use was established in Germany in 2011. Since then, pharmaceutical companies and wholesalers have been legally obliged to report annual volumes of veterinary antimicrobial ...
Lydia M Köper, Christoph Bode, Alice Bender, Inke Reimer, Thomas Heberer, Jürgen Wallmann   +5 more
doaj   +1 more source

Evaluating the OH-EpiCap tool using the Danish integrated surveillance program for AMU and AMR as a case study

Frontiers in Public Health, 2023
Antimicrobial resistance (AMR) is considered a One Health (OH) challenge, ideally demanding concerted efforts from the animal, human and environmental side.
Pedro Moura, Birgitte Borck Høg, Lis Alban, Lis Alban, Ute Wolff Sönksen, Ana Sofia Ribeiro Duarte, Marianne Sandberg   +6 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Laboratory Surveillance, Quality Management, and Its Role in Addressing Antimicrobial Resistance in Africa: A Narrative Review

Antibiotics, 2023
AMR is a major public health concern that calls for extensive work and a multidisciplinary team approach. The high prevalence of infectious diseases in African nations leads to widespread antibiotic usage and eventual antimicrobial resistance, which has ...
Khalid Musa, Ijeoma Okoliegbe, Tassabeeh Abdalaziz, Ahmed Taha Aboushady, John Stelling, Ian M. Gould   +5 more
doaj   +1 more source