Results 41 to 50 of about 11,583 (90)

Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama, Hikari Sada, Takeshi Nanjo   +2 more
wiley   +1 more source

Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies

European Journal of Haematology, Volume 116, Issue 3, Page 204-214, March 2026.
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Positively Charged Polymers Based on Cyclodextrins for Trametinib and Selumetinib Delivery in Glioblastoma Cancer

ChemMedChem, Volume 21, Issue 3, 12 February 2026.
β‐cyclodextrin‐based multicharged polymers—linear or cross‐linked—enhance the delivery of mitogen‐activated protein kinase inhibitors (selumetinib, trametinib) in glioblastoma cells. These carriers enhance the antiproliferative effect of the drugs and strengthen extracellular signal‐regulated kinase pathway inhibition.
Noemi Bognanni, Maria Teresa Gentile, Antonia Feola, Valentina Giglio, Martina Dragone, Carla Isernia, Graziella Vecchio   +6 more
wiley   +1 more source

Substantial Increase in the Costs of Antineoplastic Agents in the USA from 2010 to 2021. [PDF]

Clinicoecon Outcomes Res
Althemery AU.
europepmc   +1 more source

Risk Stratification for Cardiotoxicity in Childhood Cancer Survivors: State-of-the-Art Review and a Novel Two-Step Approach. [PDF]

Cancers (Basel)
Guida F, Fabi M, Balducci A, Zama D, Masetti R, Mercolini F, Belotti T, Cantarini ME, Facchini E, Legnani EL, Melchionda F, Bartolacelli Y, Ciuca C, Gesuete V, Prete A, Donti A, Lanari M.   +16 more
europepmc   +1 more source

Concurrent Administration of Triazoles with Chemotherapeutic and/or Immunosuppressant Agents Known to Have Moderate-to-Severe Drug-Drug Interactions in Patients with Hematologic Malignancies Hospitalized for Invasive Aspergillosis. [PDF]

Mycopathologia
Walsh TJ, Coleman CI, Johnson MD, Lovelace B, Alexander BD.   +4 more
europepmc   +1 more source

Exploratory analysis of gene aberrations and chemotherapy response: findings from a real-world database in Japan. [PDF]

Br J Cancer
Ishibashi N, Kamatani T, Aoyama S, Tokunaga M, Kinugasa Y, Ikeda S.   +5 more
europepmc   +1 more source

Evaluating temozolomide for pediatric adamantinomatous craniopharyngiomas using microspheroid-based drug screening. [PDF]

Childs Nerv Syst
Cavalheiro S, Pavon LF, de Farias CB, da Silva NS, Nascimento FB, Sibov TT, Rodrigues JB, Dastoli PA, Suzuki FS, Watanabe RA, Kim IHT, Lichtenfels M, da Silva CA, Cappellano A, da Costa MDS.   +14 more
europepmc   +1 more source

Bioaccumulation and toxicity of imatinib, cyclophosphamide and its transformation product carboxyphosphamide in the freshwater mussel Elliptio complanata. [PDF]

Ecotoxicology
Eysseric E, Vlassopoulos L, André C, Gagné F, Gagnon C.   +4 more
europepmc   +1 more source

Translational Aspects of DNA Damage Repair in Optimizing Cancer Chemotherapy. [PDF]

Adv Genet (Hoboken)
Lin A, He J, Jiang A, Zhang J, Cheng Q, Zhang H, Mao W, Luo P.   +7 more
europepmc   +1 more source