Results 141 to 150 of about 21,581 (165)

Stable Porous Organic Cage Nanocapsules for pH-Responsive Anticancer Drug Delivery for Precise Tumor Therapy. [PDF]

ACS Appl Bio Mater
Deng Y, Du Z, Du S, Li N, Wang W, Su K, Yuan D.   +6 more
europepmc   +1 more source

Exploring the anticancer potential of Hewittia malabarica through phytochemical analysis and molecular docking study. [PDF]

Sci Rep
Thozhukkad Moosaripparambil S, Vadakkadath Meethal K.   +1 more
europepmc   +1 more source

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Molecular Docking Studies and Inhibition Properties of Some Antineoplastic Agents against Paraoxonase-I.

Anti-Cancer Agents in Medicinal Chemistry, 2020
BACKGROUND In these days, most of the drugs used in clinical applications show their pharmacological influences by inhibiting or activating enzymes. Therefore, enzyme inhibitors have an essential place in the drug design for many diseases.
Yeliz Demir, Cüneyt Türkeş, Ş. Beydemir   +2 more
semanticscholar   +1 more source

Research progress on the antitumour mechanism of α-Mangostin

, 2019
α-Mangostin is the most bioactive anoxanthone compound isolated from the shell of mangosteen. Many studies have found that α-Mangostin has antitumor effect, such as that it can induce cell cycle arrest, inhibit cell survival, induce apoptosis and ...
Bin Zhao, Xiangyin Wang, Xiaolong Wang, Song Tang, J. Mao   +4 more
semanticscholar   +1 more source

Anticancer effect of lupeol, a triterpene

, 2012
Lupeol,a triterpene,is found in various edible and medicinal plants.Lupeol has been shown to exhibit strong anti-inflammatory,anti-arthritic,gene mutation prevention and anti-malarial effect.Recently,it is found that lupeol is the main active ingredients
Lin Zhang, You-cheng Zhang
semanticscholar   +1 more source

Plant extract anti-cancer research progress

, 2012
Plant extracts are kinds of important anticancer drugs.Anticancer drugs research has focused on several important plant extracts such as resveratrol,ricin,epigallocatechin-3-gallate,oridonin,juglone,quercetin,matrine,nordihydroguaiaretic acid.In vitro ...
Jian-bin Zhang, Chen Chen, Z. Tao
semanticscholar   +1 more source

The mechanisms of taxanes resistance in the treatment of breast cancer

, 2009
Recent studies show that taxanes resistances may be positively associated with overexpression of MRP protein,the change of β-microtuble,thus negatively associated with the expression of HER-2.The therapies which are specific to these targets will reverse
T. Yan, Yanping Lin
semanticscholar   +1 more source

Rational drug design of antineoplastic agents using 3D-QSAR, cheminformatic, and virtual screening approaches.

Current Medicinal Chemistry, 2019
BACKGROUND Computer-Aided Drug Design has strongly accelerated the development of novel antineoplastic agents by helping in the hit identification, optimization, and evaluation.
J. Vučićević, K. Nikolić, John B. O. Mitchell   +2 more
semanticscholar   +1 more source

Next Generation Antineoplastic Agents: A Review on Structurally Modified Vinblastine (VBL) Analogues.

Current Medicinal Chemistry, 2018
BACKGROUND Throughout the history of human civilizations, cancer has been a major health problem. Despite the advancements made by modern medical sciences, complete treatment or removal of cancerous cells is still a challenging task.
Ashanul Haque, M. Rahman, Md. Serajul Haque Faizi, Muhammad S. Khan   +3 more
semanticscholar   +1 more source

Exposure to Antineoplastic Agents Induces Cytotoxicity in Nurse Lymphocytes: Role of Mitochondrial Damage and Oxidative Stress

Iranian journal of pharmaceutical research, 2018
Cytotoxicity and mitochondrial parameters were studied in isolated lymphocytes and their mitochondria obtained from occupationally exposed nurses through inhalation exposure to antineoplastic drugs and results were compared to those of unexposed nurses ...
M.A. Eghbal, Elham Yusefi, Maria Tavakoli-Ardakani, M. Ramazani, M. Zarei, A. Salimi, J. Pourahmad   +6 more
semanticscholar   +1 more source