Results 211 to 220 of about 49,110 (259)

Tumor Microenvironment‐Responsive Nanomedicines for Potentiating Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Strategies for TME‐responsive Nanomaterials to Potentiate Cancer Immunotherapy. Abstract Immunotherapy has emerged as a transformative paradigm in oncology, yet its clinical efficacy remains constrained by the immunosuppressive tumor microenvironment and inadequate spatiotemporal control of existing modalities, resulting in suboptimal patient response ...
Qianqian Huang   +7 more
wiley   +1 more source

Fluorescence Guided Surgery in Gastric Cancer: What Do We Have and What Can We Do?

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background and Objective Fluorescence imaging has emerged as a valuable adjunct in gastric surgery, enhancing resection precision and oncologic outcomes. However, the use of indocyanine green (ICG) remains controversial due to uncertainties in efficacy and administration. A lack of standardized protocols persists.
Chun Zhuang, Han‐Kwang Yang
wiley   +1 more source

Impact of Sarcopenia During Induction Treatment in Patients With Unresectable Locally Advanced Pancreatic Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Chemotherapeutic advances have increased opportunities for conversion surgery (CS) in unresectable locally advanced (UR‐LA) pancreatic cancer (PC). However, the optimal indications for CS remain unclear. Sarcopenia has been associated with poor outcomes in PC, except UR‐LA PC. Herein, we aimed to evaluate the impact of sarcopenia on
Sho Uemura   +8 more
wiley   +1 more source

Integrating Immune Checkpoint Inhibitors With Total Neoadjuvant Therapy in Proficient Mismatch Repair Rectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The key to unlocking ICI benefit in pMMR/MSS LARC is to convert “cold” tumors into “hot” ones through lymphocyte‐sparing SCRT and judicious chemotherapy, creating a milieu in which ICIs can act effectively. ABSTRACT The management of locally advanced rectal cancer (LARC) has evolved with the adoption of total neoadjuvant therapy (TNT), integrated ...
Yoshinori Kagawa   +5 more
wiley   +1 more source

Impact of Low Preoperative Prognostic Immune Nutritional Index on Survival and Postoperative Infectious Complications in Patients With Colorectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim The prognostic immune nutritional index (PINI) is increasingly recognized for its potential clinical utility. However, multifaceted evaluations of its ability to predict oncological outcomes in colorectal cancer (CRC) and its association with postoperative infectious complications remain limited.
Shinji Yamashita   +9 more
wiley   +1 more source

Feasibility of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) in a Rabbit Model of Peritoneal Metastases: PIPALIM Project. [PDF]

open access: yesAnn Surg Oncol
Bardet SM   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy