Results 221 to 230 of about 49,110 (259)

Potential Survival Benefit of Adjuvant Chemotherapy in Stage IV Intrahepatic Cholangiocarcinoma: A Multicenter, Stage‐Stratified Analysis

Annals of Gastroenterological Surgery, EarlyView.
This multicenter study suggests that adjuvant chemotherapy may improve survival in stage IV intrahepatic cholangiocarcinoma after resection, with S‐1 showing a potential survival advantage. ABSTRACT Background The survival benefit of adjuvant chemotherapy (AC) in intrahepatic cholangiocarcinoma (ICC) remains uncertain, particularly in advanced‐stage ...
Hisashi Kosaka, Masaki Ueno, Hiroji Shinkawa, Yusuke Yamamoto, Masahiko Kinoshita, Koji Komeda, Tsukasa Aihara, Satoshi Yasuda, Haruki Mori, Masaki Kaibori   +9 more
wiley   +1 more source

Venetoclax combined with azacitidine in elderly acute myeloid leukemia: A retrospective comparison of 14-day vs 28-day dosing regimens. [PDF]

Medicine (Baltimore)
Yu Z, Li S, Pei R, Lu Y, Wang Y, Yuan J.
europepmc   +1 more source

Natural Polyphenol–Metal Supramolecular Nanocomplex for Ferroptosis Activation in Chemoresistant Hepatocellular Carcinoma

Aggregate, EarlyView.
This study presents a supramolecular nanocomplex assembled from a natural polyphenol and Cu(II) that enables cascade glutathione (GSH) depletion through synthesis inhibition, redox cycling, and Michael addition. The system induces dual cytoplasmic and mitochondrial ferroptosis in cisplatin‐resistant hepatocellular carcinoma (HCC), reverses drug ...
Yan Qin, Jialong Fan, Yi Zhang, Wei Yang, Jianzhong Cao, Bin Liu, Qing He   +6 more
wiley   +1 more source

Intermediate-dose cytarabine alone versus combination in consolidation therapy for non-transplant acute myeloid leukemia: a retrospective study. [PDF]

Ann Med
Liu Y, Wang Z, Chen T, Zhou L, He Q, Deng X, Long K, Zou X.   +7 more
europepmc   +1 more source

Intelligent Theranostic Systems Enabled by Aggregation‐Induced Emission in Precision Medicine

Aggregate, EarlyView.
Aggregation‐induced emission (AIE) luminogens are driving a new generation of intelligent theranostic systems that integrate high‐fidelity imaging and multifunctional therapy. This review highlights how AIEgens, through restriction of intramolecular motion (RIM), enable deep‐tissue NIR‐II imaging, ultrasensitive biosensing, CRISPR‐assisted gene ...
Qinqin Huang, Yanyu Chen, Shile Wang, Kan Liu, Xing‐Zhong Zhao, Xiaobo Mao, Ben Zhong Tang, Lang Rao   +7 more
wiley   +1 more source

Is switching to T-DM1 still justified in HER2-negative residual breast cancer after neoadjuvant systemic therapy? [PDF]

Breast
Tjalma W, Teuwen LA, Altintas S, Papadimitriou K.   +3 more
europepmc   +1 more source

Magnetic Soft Robots for Targeted Bacterial Delivery and Enhanced Tumor Spheroid Disaggregation

Advanced Intelligent Systems, EarlyView.
Magnetic soft robots encapsulating probiotic bacteria offer a new strategy for targeted cancer therapy. These millimeter‐scale hydrogel robots enable magnetically guided delivery, controlled bacterial release, and enhanced tumor spheroid disintegration.
Tamara Krauss, Oncay Yasa, Vitaly Pustovalov, Miriam Filippi, Salvador Pané, Robert Kevin Katzschmann   +5 more
wiley   +1 more source

The efficacy and safety of immune combination therapy in patients with driver gene-negative non-small cell lung cancer with liver metastasis: a systematic review and network meta-analysis. [PDF]

BMC Cancer
Zhao W, Li B, Gu Y, Jin X, Li Z, Guo W, Lu X, Jiang J.   +7 more
europepmc   +1 more source

Establishment of a patient‐derived drug‐resistant oral squamous cell carcinoma animal model

Animal Models and Experimental Medicine, EarlyView.
Patient‐derived xenograft (PDX) tissues from less‐responsive groups (larger tumors) were serially passaged. Sequential passaging and drug exposure in PDX models recapitulated clinical tumor evolution, enabling the development of drug‐resistant oral squamous cell carcinoma (OSCC) models. This study can offer methodological insights for precision therapy
Chuanni Feng, Hao Liu, Yalan Lu, Yanfeng Xu, Xinghan Wu, Jinlong Wang, Chuan Qin, Binbin Li, Yanhong Li   +8 more
wiley   +1 more source

Digitalization and Standardization Oncology Drug Therapy Plans with the Onkopti Database for Online Publication and Import into Software.

Oncology
Link H, Wickenkamp A, Dresel A, Link M, Link-Rachner CS, van Lengen RH, Link H.   +6 more
europepmc   +1 more source