Multifocal primary cutaneous extranodal NK/T lymphoma nasal type [PDF]
Anais Brasileiros de Dermatologia, 2016 Nasal type extranodal NK/T-cell lymphoma is a distinct entity according to the World Health Organization classification. Although 60% to 90% of patients with this disease present with a destructive mass in the midline facial tissues, it may also ...
Pedro de Vasconcelos +3 more
doaj +1 more source
Interventions for preventing oral mucositis for patients with cancer receiving treatment [PDF]
, 2003 Background: Treatment of cancer with chemotherapy is becoming increasingly more effective but is associated with short and long-term side effects. Oral side effects remain a major source of illness despite the use of a variety of agents to prevent them ...
Bryan, Gemma +8 more
core +2 more sources
Gestational trophoblastic disease [PDF]
Archive of Oncology, 2002 Gestational trophoblastic disease belongs to a spectrum of rare tumors originating from trophoblast. It spreads from the benignant disease uncomplicated partial mole to the most malignant choriocarcinoma in stage IV of disease with brain metastases ...
Živaljević Milica +4 more
doaj +1 more source
Adverse drug reaction: a comparative analysis of protocols used for treatment of colorectal cancer
Medicina, 2017 Study design: Cohort study Objective: Analyze the adverse reactions that occurred in Brazilian patients with colorectal cancer submitted to chemotherapy with two different protocols, in order to identify the types and severity of those most frequent ...
Marcela Maciel Melo +2 more
doaj +1 more source
Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs [PDF]
, 2016 Cachexia affects the majority of cancer patients, with currently no effective treatments. Cachexia is defined by increased fatigue and loss of muscle function resulting from muscle and fat depletion.
Barreto, Rafael +5 more
core +2 more sources
Xeloda as first-line therapy of metastatic colorectal cancer-our experience [PDF]
Archive of Oncology, 2002 BACKGROUND: Results of phase III clinical studies comparing efficacy of Xeloda vs. standard 5-FU/FA protocols as first line therapy of metastatic colorectal carcinoma (MCRC), have shown better efficacy of Xeloda, with less toxic adverse effects, apart ...
Kovčin Vladimir +4 more
doaj +1 more source
Dental anomalies in children submitted to antineoplastic therapy [PDF]
, 2014 Cancer is the third most frequent cause of death in children in Brazil. Early diagnosis and medical advances have significantly improved treatment outcomes, which has resulted in higher survival rates and the management of late side effects has become ...
Carrillo, Camila Merida +4 more
core +5 more sources
Ranolazine Attenuates Trastuzumab-Induced Heart Dysfunction by Modulating ROS Production [PDF]
, 2018 The ErbB2 blocker trastuzumab improves survival in oncologic patients, but can cause cardiotoxicity. The late Na+ current inhibitor ranolazine has been shown to counter experimental HF, including doxorubicin cardiotoxicity (a condition characterized by ...
Carlo G. Tocchetti +16 more
core +3 more sources
An upgrade on the rabbit model of anthracycline-induced cardiomyopathy: shorter protocol, reduced mortality, and higher incidence of overt dilated cardiomyopathy [PDF]
, 2015 Current protocols of anthracycline-induced cardiomyopathy in rabbits present with high premature mortality and nephrotoxicity, thus rendering them unsuitable for studies requiring long-term functional evaluation of myocardial function (e.g., stem cell ...
Brooks, Gavin +6 more
core +7 more sources
Vandetanib has antineoplastic activity in anaplastic thyroid cancer, in vitro and in vivo [PDF]
, 2018 The antitumor activity of vandetanib [a multiple signal transduction inhibitor including the RET tyrosine kinase, epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF) receptor (VEGFR), ERK and with antiangiogenic activity ...
Antonelli, Alessandro +17 more
core +2 more sources