Results 51 to 60 of about 288,402 (222)
Inorganic Nanomaterials Meet the Immune System: An Intricate Balance
Advanced Healthcare Materials, EarlyView.Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli +3 more
wiley +1 more source
Sequential dose-dense single agent chemotherapy for locally advanced breast cancer [PDF]
Archive of Oncology, 2003 Chemotherapy of breast cancer is still the area of intensive research. Based on mathematical model of tumor cell growth kinetics, articulated by Larry Norton, novel concept of chemotherapy in breast cancer was launched and it implies dose-densification ...
Vrbić Svetislav +3 more
doaj +1 more source
Limiting the Development of Anti-Cancer Drug Resistance in a Spatial Model of Micrometastases [PDF]
arXiv, 2016 While chemoresistance in primary tumors is well-studied, much less is known about the influence of systemic chemotherapy on the development of drug resistance at metastatic sites. In this work, we use a hybrid spatial model of tumor response to a DNA damaging drug to study how the development of chemoresistance in micrometastases depends on the drug ...
arxiv
An Efficient Consolidation of Word Embedding and Deep Learning Techniques for Classifying Anticancer Peptides: FastText+BiLSTM [PDF]
arXiv, 2023 Anticancer peptides (ACPs) are a group of peptides that exhibite antineoplastic properties. The utilization of ACPs in cancer prevention can present a viable substitute for conventional cancer therapeutics, as they possess a higher degree of selectivity and safety.
arxiv
Advanced Healthcare Materials, EarlyView.An injectable, adhesive hydrogel integrating 2D‐MoS2 and 5‐fluorouracil (AlgNB/MoS2/5‐FU) is developed for near‐infrared‐triggered photothermal therapy and localized drug delivery. The adhesive hydrogel demonstrates superior tumor anchoring, efficient photothermal conversion, and synergistic inhibition of colorectal cancer progression, offering a ...
Xiaojun Long +8 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Short‐chain fatty acids modulate anti‐ROR1 chimeric antigen receptor (CAR) T‐cell function in an intestinal adenocarcinoma‐on‐chip model. Butyrate and propionate reduce cytotoxicity, cytokine release, and infiltration by inducing a regulatory T‐cell phenotype and T‐cell exhaustion via histone deacetylase inhibition.
Valentin D. Wegner +5 more
wiley +1 more source
Diferenças no tratamento sistêmico do câncer no Brasil: meu SUS é diferente do teu SUS
Brazilian Journal of Oncology, 2017 Objetivo: Identificar diferenças no tratamento sistêmico dos quatro tipos mais incidentes de câncer tratados no SUS e comparar os tratamentos oferecidos com as Diretrizes Terapêuticas (DTs) estabelecidas pelo Ministério da Saúde (MS), assim ...
Rafael Aliosha Kaliks +3 more
doaj +1 more source
Cell-permeable tumor suppressor peptides for cancer therapy: back to the future [PDF]
arXiv, 2007 Miniaturization is a hallmark of modern technologies. Notably, this feature has not spared molecular biology and its potential applications. Towards developing more effective therapeutics against cancer, studies began to explore more than a decade ago how natural tumor suppression could be translated into antineoplastic drugs.
arxiv
Effects of drug resistance in the tumour-immune system with chemotherapy treatment [PDF]
arXiv, 2020 Cancer is a term used to refer to a large set of diseases. The cancerous cells grow and divide and, as a result, they form tumours that grow in size. The immune system recognise the cancerous cells and attack them, though, it can be weakened by the cancer. One type of cancer treatment is chemotherapy, which uses drugs to kill cancer cells.
arxiv
Automatic brain tumor grading from MRI data using convolutional neural networks and quality assessment [PDF]
, 2018 Glioblastoma Multiforme is a high grade, very aggressive, brain tumor, with patients having a poor prognosis. Lower grade gliomas are less aggressive, but they can evolve into higher grade tumors over time. Patient management and treatment can vary considerably with tumor grade, ranging from tumor resection followed by a combined radio- and ...
arxiv +1 more source