Results 101 to 110 of about 530,203 (233)

An Atypical Skin Presentation of Adult‐Onset Still's Disease With Histological Description: A Case Report

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Adult‐onset Still's disease (AOSD) is an auto inflammatory disorder with a variable clinical presentation, and without a pathognomonic diagnostic test, characterized by high spiking fever, arthralgia/arthritis, a suggestive skin rash, elevated white blood cell count 10 G/L (> 80% neutrophils), elevated ferritin, with glycosylated ferritin < 20%
M. Nordmann, T. Mazza, S. Menzinger, G. Kaya, S. Bogiatzi, S. Vandenberghe‐Dürr, M. Blanchard, J. Stirnemann   +7 more
wiley   +1 more source

Review Article - Antinuclear Antibodies: Clinical Applications

, 2000
One of the common serological hallmarks of autoimmune disorders is the presence of various autoantibodies in the sera of patients affected by these disorders.
A. Wanchu
core   +2 more sources

Systemic lupus erythematosus and nephritis: severe relapse with disappearance of antinuclear antibodies.

, 1980
Exacerbations of systemic lupus erythematosus with active renal disease are almost always associated with high plasma titres of antinuclear factor (ANF) and DNA-binding antibody (anti-ds DNA).
White, Nicholas, Ledingham, JG, Winearls, CG   +2 more
core   +1 more source

Utility of IL‐18 Immunohistochemistry in Distinguishing Dermatomyositis and Lupus Erythematosus in Skin Biopsies

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Distinction of dermatomyositis (DM) and cutaneous lupus erythematosus (LE) in skin biopsies is often difficult due to significant histopathologic overlap. Prior transcriptional analysis has identified upregulation of IL‐18 in DM compared with LE.
Steven M. Hrycaj, Joseph S. Durgin, Johann E. Gudjonsson, J. Michelle Kahlenberg, Gaidaa R. Majari, Carole Bitar, Catherine G. Chung, Rosalynn M. Nazarian, May P. Chan   +8 more
wiley   +1 more source

Antinuclear antibodies giving the 'multiple nuclear dots' or the 'rim-like/membranous' patterns: diagnostic accuracy for primary biliary cirrhosis.

, 2006
BACKGROUND: Serum antinuclear antibodies giving the 'multiple nuclear dots' or the 'rim-like/membranous' patterns are frequently detected by indirect immunofluorescence on HEp-2 cells in patients with primary biliary cirrhosis.
Worthington, J, Bianchi, FB, DE Molo, C, M. GUIDI, M. LENZI, P. MURATORI, F. B. BIANCHI, Pappas, G, G. PAPPAS, Muratori, P, Cassani, F, Chapman, RW, F. CASSANI, A. GRANITO, J. WORTHINGTON, Guidi, M, Ferri, S, S. FERRI, Muratori, L, Granito, A, C. DE MOLO, R. W. CHAPMAN, L. MURATORI, Lenzi, M   +23 more
core   +1 more source

Association between Antinuclear Antibodies Patterns and Immunological Markers with Systemic Lupus Erythematosus in Iraqi Female Patients [PDF]

Background: Systemic lupus erythematosus is a condition where the immune system attacks various tissues and organs, affecting commonly women between the ages of 15 to 44. It is caused by genetics or environmental factors.
Humaish, Haider Hafudh, Zeki, Ali Yahya, Al-Hafid, Ali Hussein   +2 more
core   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Detection of antinuclear antibodies by indirect immunofluorescence and by solid phase assay

, 2011
Testing for antinuclear antibodies is useful for the diagnosis of systemic rheumatic diseases. Solid phase assays are increasingly replacing indirect immunofluorescence for detection of antinuclear antibodies. In the most recent generation of solid phase
Vermeersch, Pieter, Patrick Verschueren, Mariën, Godelieve, René Westhovens, Katrijn Op De Beeck, Verschueren, Patrick, Pieter Vermeersch, Daniel Blockmans, Westhovens, René, Xavier Bossuyt, Bossuyt, Xavier, Blockmans, Daniel Engelbert, Op De Beeck, Katrijn, Godelieve Mariën   +13 more
core   +1 more source

Charting the course of Sjögren's disease: A historical analysis of scientific progress

European Journal of Oral Sciences, EarlyView.
Abstract Sjögren's disease (SjD) bears the name of the Swedish ophthalmologist Henrik Sjögren. His 1933 doctoral thesis on keratoconjunctivitis sicca ignited interest, yet much remains under debate. SjD is an autoimmune disorder that primarily affects the exocrine glands, particularly the salivary and lacrimal glands, leading to a dryness of the eyes ...
Diego Ustárroz Cantali, Fabiola Reis de Oliveira, Denise Cantarelli Machado, Moisés Evandro Bauer   +3 more
wiley   +1 more source

Evaluating plasma antinuclear autoantibody profile as a prognostic biomarker in lymphoma

BMC Cancer
Background Research on the antinuclear antibodies (ANA) profile across different pathological subtypes of lymphoma was limited. Our study aimed to assess ANA profile and investigate its potential prognostic value in lymphoma.
Cuiling Zheng, Ruyun Gao, Yanrong Wang, Xiaohong Han   +3 more
doaj   +1 more source