Results 71 to 80 of about 60,641 (297)

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell‐Targeted Therapies

Arthritis &Rheumatology, Accepted Article.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no FDA‐approved disease‐modifying therapies for SjD.
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Serum antibodies in first-degree relatives of patients with IBD: A marker of disease susceptibility? A follow-up pilot-study after 7 years [PDF]

, 2005
Introduction: Various disease-specific serum antibodies were described in patients with inflammatory bowel disease and their yet healthy first-degree relatives.
H.P. Török, J. Glas, H.C. Hollay, R. Gruber, M. Osthoff, L. Tonenchi, C. Brückl, T. Mussack, M. Folwaczny, C. Folwaczny, Glas J, Quinton JF, Ruemmele FM, Cambridge G, Colombel JF, Shanahan F, Hoffman IE, Torok HP, Seibold F, Folwaczny C, Folwaczny C, Folwaczny C, Seibold F, Shanahan F, Folwaczny C, Bansi DS, Klebl FH, Klebl FH, Torok HP, Lombardi G   +29 more
core   +4 more sources

Efficacy of Telitacicept in Childhood‐Onset Systemic Lupus Erythematosus: A Prospective Multicenter Cohort Study With Inverse Probability of Treatment Weighting –Adjusted Comparison to a Historical Control Group Treated With Belimumab

Arthritis &Rheumatology, EarlyView.
Objective The therapeutic effects of telitacicept combined with standard of care (SoC) in childhood‐onset systemic lupus erythematosus (cSLE) remain unclear. This study aims to evaluate its efficacy in comparison with belimumab combined with SoC.
Chong Luo, Shu Su, Jingyue Liu, Junyu Lin, Jin Song, Zongwen Chen, Yuanyuan Peng, Lijun Jiang, Meng Jia, Li Wang, Xinhui Jiang, Wei Zhang, Zanhua Rong, Bo Zhao, Yajun Wang, Xuemei Tang   +15 more
wiley   +1 more source

Recreational exposure during algal bloom in carrasco beach, uruguay: A liver failure case report [PDF]

, 2017
In January 2015, a 20-month-old child and her family took part in recreational activities at Carrasco and Malvín beaches (Montevideo, Uruguay). An intense harmful algae bloom (HAB) was developing along the coast at that time.
Andrinolo, Dario, Caixach, Josep, Cavalieri, María Lorena, D'Agostino, Daniel, Flores, Cintia, Mullen, Eduardo, Parot Varela, María Macarena, Sedan, Daniela Yazmine, Vidal, Flavia   +8 more
core   +3 more sources

Drugs induced Raynaud's phenomenon and underlying mechanism: a disproportionality analysis from the WHO pharmacovigilance database

Arthritis &Rheumatology, Accepted Article.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's Phenomenon (RP) and to explore their potential pathophysiological mechanisms through a mixed disproportionality/clustering analysis from the WHO pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

Late onset systemic sclerosis with seronegativity: a rare presentation of an uncommon disease

Reumatismo, 2019
Systemic sclerosis (SSc) is an uncommon connective tissue disorder characterized by multisystem involvement with fibrosis of skin and internal organs. Antibody formation is one of the hallmarks of SSc.
D. Saxena, D. Jain, M. Yadav, K. Giri, T. Yadav, P. jain   +5 more
doaj   +1 more source

Autoantibodies in Wilson disease: Impact on clinical course

JIMD Reports, 2022
Symptoms of Wilson disease (WD) vary and additional factors such as autoimmunity may play an important role in WD pathogenesis. The presence of antinuclear antibodies (ANA), anti‐neutrophil cytoplasmic antibodies, neuronal surface antibodies, and ...
Magdalena Antczak‐Kowalska, Anna Członkowska, Ceren Eyileten, Anna Palejko, Agnieszka Cudna, Marta Wolska, Agnieszka Piechal, Tomasz Litwin   +7 more
doaj   +1 more source

Definições para a padronização da pesquisa de auto-anticorpos contra constituintes do núcleo (FAN HEp-2), nucléolo, citoplasma e aparelho mitótico e suas associações clínicas [PDF]

, 2003
OBJECTIVE: The Second Brazilian Consensus on Antinuclear Antibodies (ANA) in HEp-2 Cells approved and extended the decision trees developed during the First Brazilian Consensus in order to also offer information about mixed patterns of fluorescence ...
Andrade, Luiz Eduardo Coelho, Araújo, Flávia Ikeda e, Bichara, Carlos David Araújo, Bonfá, Eloisa Silva Dutra de Oliveira, Callado, Maria Roseli, Carballo, Orlando Gabriel, Carvalho, Darlene Gonçalves, Cintra, Alice Friedenberg de Ulhôa, Cruvinel, Wilson de Melo, Dellavance, Alessandra, Doi, Elvira M., Francescantonio, Paulo Luiz Carvalho, Gabriel Júnior, Alexandre, Guimarães, Fabiana Nunes de Carvalho, Jarach, Renata, Leser, Paulo Guilherme, Levy, Roger Abramino, Mangueira, Cristóvão Luis Pitangueiras, Mesquita, Mauro Meira, Moreira, Caio, Mundim, Hugo Mendonça, Neves, Suzane Pretti Figueiredo, Nuccitelli, Barbara, Poli, Luciana, Rego, Jozelia, Santos, Cláudio Henrique Ramos dos, Santos, Wilton Silva dos, Silva, Nilzio Antônio da, Slhessarenko, Natasha, Sugiyama, Mitiko, Taliberti, Ben Hur, Vieira, Lisiane Ericonio dos Anjos, Von Mühlen, Carlos Alberto, Xavier, Ricardo Machado, Ximenes, Antônio Carlos, Yano, Cristiane Martinez   +35 more
core   +3 more sources

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: the Randomized, Phase 3, TULIP‐SC Study

Arthritis &Rheumatology, Accepted Article.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate‐to‐severe SLE activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly for 52 weeks (1:1 ...
Susan Manzi, Ian N. Bruce, Eric F. Morand, Richard Furie, Yoshiya Tanaka, Kenneth C. Kalunian, Anca Askanase, Patricia Puzio, Emon Khan, Jenny Wissmar, Michael Song, Catharina Lindholm, The TULIP‐SC investigators   +12 more
wiley   +1 more source

Fator antinúcleo na dermatologia Antinuclear factor in dermatology

Anais Brasileiros de Dermatologia, 2005
Trata-se de artigo de revisão e atualização sobre a pesquisa dos anticorpos antinucleares, em especial do fator antinúcleo, em que são abordados os aspectos históricos, epidemiológicos, fisiopatogenia, métodos de identificação, suas especificidades e ...
Artur Antônio Duarte
doaj   +1 more source