Emerging role of nuclear factor erythroid 2-related factor 2 in the mechanism of action and resistance to anticancer therapies [PDF]
, 2019 Nuclear factor E2-related factor 2 (NRF2), a transcription factor, is a master regulator of an array of genes related to oxidative and electrophilic stress that promote and maintain redox homeostasis. NRF2 function is well studied in in vitro, animal and
Deeni, Yusuf Y. +3 more
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Role of cellular senescence and NOX4-mediated oxidative stress in systemic sclerosis pathogenesis. [PDF]
, 2015 Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by progressive fibrosis of skin and numerous internal organs and a severe fibroproliferative vasculopathy resulting frequently in severe disability and high mortality.
A Diazdeleon +130 more
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Molecules, 2018 To obtain novel structural antioxidants that have different antioxidant mechanisms, four 2-(alkylthio)-N-(4-(phenylamino)phenyl)acetamides 2a–d as dual functional antioxidants are designed, synthesized, and confirmed by 1H-NMR, FTIR, MS, and elemental ...
Jun-Bo He +3 more
doaj +1 more source
Insects, 2023 Plenty of freshwater species, especially macroinvertebrates that are essential to the provision of numerous ecosystem functions, encounter higher mortality due to acute hypoxia.
Yao Zhang +6 more
doaj +1 more source
Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-inflammatory Pathways. [PDF]
, 2020 Oxidative stress and chronic inflammation play critical roles in the pathogenesis of ulcerative colitis (UC) and inflammatory bowel diseases (IBD). A previous study has demonstrated that dimethyl fumarate (DMF) protects mice from dextran sulfate sodium ...
Farzaneh, Ted +8 more
core +2 more sources
Frontiers in Plant Science, 2023 Drought is a major constraint to sugarcane (Saccharum spp.) production and improving the water use efficiency (WUE) is a critical trait for the sustainability of this bioenergy crop.
Danyel F. Contiliani +10 more
doaj +1 more source
DFT Study on Antioxidant Action Mechanisms of Naphthoquinone-Urazole Hybrids
Cumhuriyet Science Journal, 2018 The aim of this study is on the evaluation ofthe antioxidant activities of the investigated naphthoquinone-urazole hybridsby comparing our theoretical results with experimental results and on theelucidation the antioxidant action mechanisms.
Dilara Özbakır Işın
doaj +1 more source
Electrochemical behaviour of N-acetyl-l-cysteine on gold electrode—A tentative reaction mechanism [PDF]
, 2007 The electrochemical behaviour of N-acetyl-l-cysteine (NAC) has been investigated by linear and cyclic voltammetry on gold electrode at room temperature. The results showed two oxidation peaks under acid and neutral conditions and only one in basic medium.
Barus, Carole +4 more
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Comparison of stabilization by Vitamin E and 2,6-di-tert-butylphenols during polyethylene radio-thermal-oxidation [PDF]
, 2014 This paper reports a compilation of data for PE+Vitamin E and 2,6-di-tert-butylphenols oxidation in radio-thermal ageing. Data unambiguously show that Vitamin E reacts with P° and POO° whereas 2,6-di-tert-butyl phenols only react with POO°.
RICHAUD, Emmanuel
core +6 more sources
Environmental risk factors and their footprints in vivo – a proposal for the classification of oxidative stress biomarkers [PDF]
, 2020 Environmental agents, including socioeconomic condition, and host factors can act as causal agents and risk factors in disease. We use biomarkers and sociomarkers to study causal factors, such as overproduction of reactive oxygen species (ROS) which ...
Ghezzi, Pietro
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