Results 51 to 60 of about 617,591 (305)

Analysis of the Antioxidant Mechanism of Ozone Treatment to Extend the Shelf Life and Storage Quality of ‘Korla’ Fragrant Pears Based on Label-Free Proteomics

Horticulturae
In this study, the physiological indicators, reactive oxygen species (ROS) levels, and activities and expressions of key enzymes related to ROS metabolism were monitored to explore the mechanism of ozone treatment on the shelf life of postharvest Korla ...
Shaohua Lin, Xiaojun Zhang, Mo Li, Na Zhang, Chenghu Dong, Haipeng Ji, Pufan Zheng, Zhaojun Ban, Xing Mei, Changyu Gu, Cunkun Chen   +10 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Chitosan mitigates water stress in cowpea plants through modulation of growth, homeostasis, and antioxidant activities

Frontiers in Plant Science
IntroductionClimate change and population growth increase food demand, especially in semi-arid regions. Water deficit affects cowpea productivity, but foliar application of chitosan can improve its tolerance, stimulating antioxidant activity and growth ...
Rayanne Silva de Alencar, Priscylla Marques de Oliveira Viana, Guilherme Felix Dias, Semako Ibrahim Bonou, Leticia Diniz Ribeiro, Yngrid Mikhaelly Lourenço de Araujo, Igor Eneas Cavalcante, Hermes Alves de Almeida, Pedro Roberto Almeida Viégas, Alberto Soares de Melo   +9 more
doaj   +1 more source

Influence of hyperhomocysteinemia on the cellular redox state - Impact on homocysteine-induced endothelial dysfunction [PDF]

, 2003
Hyperhomocysteinemia is an independent risk factor for the development of atherosclerosis. An increasing body of evidence has implicated oxidative stress as being contributory to homocysteines deleterious effects on the vasculature.
Adachi T, Andersson A, Bagi Z, Bellamy MF, Chambers JC, Chambers JC, Chao CL, Flohé L, Forgione MA, Guttormsen AB, Huang R-FS, Kanani PM, Karlsson K, Lang D, Lentz SR, Mansoor MA, Mansoor MA, Mansoor MA, Mansoor MA, O'Donnell VB, Outinen PA, Pritchard, Rubbo H, Tawakol A, Ungvari Z, Weiss N, Wilcken DE, Woo KS, Zhang F, Zhang X   +29 more
core   +1 more source

Antioxidants and Cellular Antioxidation Mechanism in Plants

South Indian Journal of Biological Sciences, 2016
Plants exposed to various types of environmental stresses produce reactive oxygen species (ROS), within the system. ROS can bring about various types of cell injuries leading to cell death. Plants have different ant oxidation mechanisms (mediated by both enzymatic and non enzymatic antioxidants) operational in them to take care of the deleterious ROS.
openaire   +1 more source

Pulmonary Antioxidant Defense Mechanisms

Experimental Lung Research, 1985
Intrinsic enzymatic and non-enzymatic pulmonary antioxidant defense mechanisms undoubtedly protect the lung against oxidant-mediated environmental stresses and diseases. In addition, new ways of augmenting pulmonary antioxidant defenses are being developed which can be used to bolster disease-overwhelmed intrinsic lung defense mechanisms.
C W, White, J E, Repine
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Catechins: Protective mechanism of antioxidant stress in atherosclerosis

Frontiers in Pharmacology, 2023
Tea has long been valued for its health benefits, especially its potential to prevent and treat atherosclerosis (AS). Abnormal lipid metabolism and oxidative stress are major factors that contribute to the development of AS.
Yuhan Sheng, Yizhuo Sun, Yang Tang, Yanru Yu, Jiarou Wang, Fengjie Zheng, Yuhang Li, Yan Sun   +7 more
doaj   +1 more source

Efecto del estrés producido por la mezcla de sales en la concentración de aldehído malónico, proteínas y enzimas antioxidantes de Leymus chinensis de tres colores foliares diferentes [PDF]

, 2017
The mixed salt stress is common in nature. Salt stressalways affects plant growth. Different plant species have different adaptive capacity to salty soil. Leymus chinensis is an herbaceous plant with different leaf colors.
Busso, Carlos Alberto, Han, X. G., Wang, Z. W., Yang, Y. F., Yang, Y. G., Zhang, Z., Zhou, C.   +6 more
core  

Novel Findings about Double-Loaded Curcumin-in-HPβcyclodextrin-in Liposomes: Effects on the Lipid Bilayer and Drug Release [PDF]

, 2018
In this study, the encapsulation of curcumin (Cur) in “drug-in-cyclodextrin-in-liposomes (DCL)” by following the double-loading technique (DL) was proposed, giving rise to DCL–DL.
Fernández Romero, Ana María, González Rodríguez, María Luisa, Maestrelli, Francesca, Mura, Paola Angela, Rabasco Álvarez, Antonio María   +4 more
core   +2 more sources