Results 91 to 100 of about 3,678,963 (228)

Polyamine quinoline rhodium complexes: synthesis and pharmacological evaluation as antiparasitic agents against Plasmodium falciparum and Trichomonas vaginalis.

Dalton Transactions, 2015
A series of mono- and bis-salicylaldimine ligands and their corresponding Rh(i) complexes were prepared. The compounds were characterised using standard spectroscopic techniques including NMR, IR spectroscopy and mass spectrometry.
Tameryn Stringer, Dale Taylor, Hajira Guzgay, Ajit Shokar, Aaron Au, Peter J. Smith, D. Hendricks, K. Land, T. Egan, Gregory S. Smith   +9 more
semanticscholar   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

The role of T cells in sepsis of distinct infectious aetiologies

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
Pathogen‐specific sepsis induces mitochondrial dysfunction in T cells, leading to functional alterations. Single‐cell transcriptomics reveals subtype‐specific impairments involving reactive oxygen species accumulation, mtDNA damage, calcium dysregulation, and metabolic reprogramming.
Xuanqi Liu, Bijun Zhu, Wanxin Duan, Ruixiang Kang, Xiangdong Wang, Liyang Li   +5 more
wiley   +1 more source

Biodegradable Sodium Alginate Films Incorporated With Jateorhiza palmata (Lam.) Miers Extract for Active Food Packaging

Packaging Technology and Science, Volume 39, Issue 4, Page 367-382, April 2026.
Development of biodegradable sodium alginate films incorporated with J. palmata root extracts showing enhanced antioxidant and functional properties for active food packaging applications. ABSTRACT Biodegradable packaging helps reduce environmental impact by decomposing naturally and preventing plastic accumulation in ecosystems.
Carlos Augusto Badillo Almeira, Suiane Savazzi, Raul Remor Dalsasso, Alcilene Rodrigues Monteiro, Alessandro de Oliveira Rios   +4 more
wiley   +1 more source

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity [PDF]

Arch Pharm (Weinheim)
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Mousavi A, Slapničková M, Norouzbahari M, D'Alessandro S, Foroumadi P, Peytam F, Perego F, Doleželová E, Emamgholipour Z, Tehrani M, Sadat‐Ebrahimi S, Hosseinzadeh E, Ahadi E, Firoozpour L, Bijanzadeh H, Basilico N, Zíková A, Foroumadi A.   +17 more
europepmc   +2 more sources

Looking for Greener Pastures: In Vitro Screening of Phytogenics for the Control of Sparicotyle chrysophrii in Gilthead Sea Bream

Journal of Fish Diseases, Volume 49, Issue 4, April 2026.
ABSTRACT The gill parasite Sparicotyle chrysophrii poses a significant threat to gilthead sea bream (Sparus aurata) aquaculture in the Mediterranean, causing considerable mortality and economic losses. As traditional chemotherapeutic treatments, like formalin, face growing regulatory restrictions, there is an urgent need for alternative control ...
Teresa Pirollo, Ana León, Monica Caffara, Alice Caneschi, Itziar Estensoro, Jinni Gu, Maurizio Scozzoli, Ariadna Sitjà‐Bobadilla, Oswaldo Palenzuela   +8 more
wiley   +1 more source

Design and synthesis of novel bis-pyridinium based-ionic liquids as potent antiparasitic agents. [PDF]

Heliyon, 2023
Moneer EA, Bakr BA, Akl SH, Shahin YH, Elwakil BH, Hagar M, Paudel KR, Aljuhani A, Aouad MR, Rezki N.   +9 more
europepmc   +1 more source

Glycosomal Phosphoenolpyruvate Carboxykinase CRISPR/Cas9‐Deletion and Its Role in Trypanosoma cruzi Metacyclogenesis and Infectivity in Mammalian Host

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Effects of PEPCK deficiency in Trypanosoma cruzi bioenergetics and life stages. ABSTRACT Trypanosoma cruzi, the causative agent of Chagas disease, possesses glycosomes—unique organelles that house key metabolic enzymes, several of which are promising therapeutic targets.
Carolina S. D. Vieira, Wei Wang, Fernando Sanchez‐Valdez, Jihyun Lim, Brooke E. White, Camilla G. S. Souza, Rick L. Tarleton, Marcia C. Paes, Natalia P. A. Nogueira   +8 more
wiley   +1 more source

Bauerenol Acetate, the Pentacyclic Triterpenoid from Tabernaemontana longipes, is an Antitrypanosomal Agent

Molecules, 2018
The Latin American plant Tabernaemontana longipes was studied in this work as a potential source of antiparasitic agents. The chloroform extract of T. longipes leaves was separated into several fractions, and tested for antitrypanosomal activity.
Simira Carothers, Rogers Nyamwihura, Jasmine Collins, Huaisheng Zhang, HaJeung Park, William N. Setzer, Ifedayo Victor Ogungbe   +6 more
doaj   +1 more source

Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents.

European journal of medicinal chemistry, 2013
As a part of our project pointed at the search of new safe chemotherapeutic and chemoprophylactic agents against parasitic diseases, several compounds structurally related to 4-phenoxyphenoxyethyl thiocyanate (WC-9), which were modified at the terminal ...
Pablo D Elicio, María N. Chao, Melina Galizzi, Catherine Li, Sergio H. Szajnman, R. Docampo, S. Moreno, Juan B. Rodriguez   +7 more
semanticscholar   +1 more source