Results 71 to 80 of about 3,814,825 (281)

Anti-platelet agents in pediatric cardiac practice

open access: yesAnnals of Pediatric Cardiology, 2013
Pediatric patients with a variety of congenital and acquired cardiac conditions receive antithrombotic therapy. Many of the indications are empirical, and have either not been proven in controlled studies or are extrapolated from adult studies.
Sweta Mohanty, Balu Vaidyanathan
doaj   +1 more source

The Use Pattern and Clinical Impact of New Antiplatelet Agents Including Prasugrel and Ticagrelor on 30-day Outcomes after Acute Myocardial Infarction in Korea: Korean Health Insurance Review and Assessment Data

open access: yesKorean Circulation Journal, 2017
Background and Objectives Despite the favorable efficacy of new antiplatelet agents demonstrated in randomized controlled trials, their clinical implications in Korea are unclear.
Choongki Kim   +13 more
semanticscholar   +1 more source

Transcatheter Repair of Sinus Venosus Defect Using a 12‐zig Covered Cheatham‐Platinum Stent in Large Superior Vena Cava—Right Atrium Junctions: Early Multicenter Experience

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Sinus venosus defect (SVD) is a rare congenital heart anomaly characterised by an abnormal communication between the atria, often associated with partial anomalous pulmonary venous connection (PAPVC). Traditional surgical repair carries significant risks, prompting exploration into less invasive transcatheter approaches.
Alberto Fuensalida   +7 more
wiley   +1 more source

Efficacy versus safety: the dilemma of using novel platelet inhibitors for the treatment of patients with ischemic stroke and coronary artery disease

open access: yesTherapeutics and Clinical Risk Management, 2014
Gianmarco Iannopollo,1 Rita Camporotondo,2 Gaetano M De Ferrari,2 Sergio Leonardi2 1Università degli Studi di Pavia, Pavia, 2Fondazione IRCCS Policlinico San Matteo, Pavia, Italy Abstract: Coronary and cerebrovascular atherothrombosis are the ...
Iannopollo G   +3 more
doaj  

Role of Neuroimaging Before Coronary Angiography in Patients With Out‐of‐Hospital Cardiac Arrest

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Patients presenting following out‐of‐hospital cardiac arrest (OOHCA) often require emergency coronary angiography. Presentations can be associated with syncope or head‐trauma. Aims We investigated the impact and utility of pre‐coronary angiography CT‐Brain (CT‐B) in patients following OOHCA on clinical outcomes.
Edmond Wong   +8 more
wiley   +1 more source

Research advances on platelet glycoprotein VI in ischemic stroke

open access: yesThrombosis Journal
Atherosclerosis is one cause of ischemic stroke. Subcutaneous collagen is exposed when the fibrous cap of an atherosclerotic plaque ruptures. Platelets bind to collagen, leading to platelet activation, aggregation, and thrombus formation.
Hanlu Xiang   +5 more
doaj   +1 more source

Perioperative management and monitoring of antiplatelet agents: a focused review on aspirin and P2Y12 inhibitors

open access: yesKorean Journal of Anesthesiology, 2017
Platelets play pivotal roles in hemostasis as well as pathological arterial thrombosis. The combination of aspirin and a P2Y12 inhibitor has become the mainstay therapy in the ageing population with cardiovascular conditions, particularly during and ...
Michael A. Mazzeffi   +3 more
semanticscholar   +1 more source

Protective Effect of Phytic Acid in Cardiovascular Diseases: A Systematic Review

open access: yesChemFoodChem, EarlyView.
ABSTRACT Cardiovascular diseases (CVDs) are a cluster of ailments that impact the heart and blood vessels and are a primary public health problem of mortality on a global scale. Phytic acid, a dietary constituent frequently present in foods like seeds, has been linked to many pharmacological attributes, including anti‐cancer, antioxidant, anti ...
Marta M. S. de Freitas Almeida   +7 more
wiley   +1 more source

Transperineal ultrasound-guided prostate biopsy is safe even when patients are on combination antiplatelet and/or anticoagulation therapy

open access: yesBMC Urology, 2017
Background To assess whether hemorrhagic complications associated with transperineal prostate biopsy increased in patients on antiplatelet and/or anticoagulant therapy.
Kimitoshi Saito   +6 more
doaj   +1 more source

Impact of CYP2C19 and CYP3A4 Inhibitor Use on Clopidogrel Clinical Effectiveness in CYP2C19 Genotyped Patients Undergoing Percutaneous Coronary Intervention

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 and CYP3A4 contribute to clopidogrel bioactivation. CYP2C19 no‐function alleles diminish clopidogrel's antiplatelet effects and clinical effectiveness. Coadministration of either a CYP2C19 or a CYP3A4 inhibitor may also reduce clopidogrel's antiplatelet effects and lead to phenoconversion in patients without a CYP2C19 no‐function allele (normal/
Danwei Shao   +8 more
wiley   +1 more source

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