Results 321 to 330 of about 3,264,242 (368)

Atypical antipsychotic agents: A critical review

American Journal of Health-System Pharmacy, 2000
The pharmacology, efficacy, and adverse effects of atypical antipsychotic agents when used to treat schizophrenia and other disorders are reviewed. Atypical antipsychotic agents were developed in response to problems with typical agents, including lack of efficacy in some patients, lack of improvement in negative symptoms, and troublesome adverse ...
Jodi A. Worrel, Stephanie E. Beckman, Patricia A. Marken, Valerie L. Ruehter   +3 more
openaire   +3 more sources

Prevalence and predictors of lipid and glucose monitoring in commercially insured patients treated with second-generation antipsychotic agents.

American Journal of Psychiatry, 2009
OBJECTIVE The authors sought to quantify plasma lipid and glucose testing rates in patients receiving second-generation antipsychotics before and after guidelines recommending testing were issued in February 2004 by the American Diabetes Association (ADA)
D. Haupt, L. Rosenblatt, Edward Kim, R. Baker, R. Whitehead, J. Newcomer   +5 more
semanticscholar   +1 more source

Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors: design, synthesis, and effects on behavior.

Journal of Medicinal Chemistry, 2009
Dopamine D(3) antagonism combined with serotonin 5-HT(1A) and 5-HT(2A) receptor occupancy may represent a novel paradigm for developing innovative antipsychotics.
S. Butini, S. Gemma, G. Campiani, S. Franceschini, F. Trotta, M. Borriello, N. Ceres, S. Ros, Salvatore Sanna Coccone, Matteo Bernetti, M. De Angelis, M. Brindisi, V. Nacci, I. Fiorini, E. Novellino, A. Cagnotto, T. Mennini, K. Sandager‐Nielsen, J. T. Andreasen, J. Scheel-Kruger, J. Mikkelsen, C. Fattorusso   +21 more
semanticscholar   +1 more source

Chapter 1. Antipsychotic Agents

1988
Publisher Summary The emerging technologies of functional and anatomical brain imaging are finding more frequent application in the study of brain structural abnormalities that may underlie the etiology of schizophrenia. New insight into the role of the regional distribution and receptor binding of anti-psychotic agents has been brought by ...
Katherine S. Takaki, J. S. New
openaire   +2 more sources

Preparation of derivatives of 1-(2-pyrimidinyl)piperazine as potential antianxiety, antidepressant, and antipsychotic agents

, 2008
This paper describes the preparation of twenty-eight derivatives of 1-(2-pyrimidinyl)piperazine as potential antianxiety, antidepressant, and antipsychotic agents.
I. Becker
semanticscholar   +1 more source

Antipsychotic agents and sudden cardiac death--how should we manage the risk?

New England Journal of Medicine, 2009
Antipsychotic medications are commonly used across the entire age spectrum, both within and outside their labeled (and evidence-based) indications.1,2 Three atypical antipsychotic medications, olan...
S. Schneeweiss, J. Avorn
semanticscholar   +1 more source

Depression in schizophrenia: perspective in the era of "Atypical" antipsychotic agents.

American Journal of Psychiatry, 2000
OBJECTIVE The author sought to provide a contemporary understanding of depression in schizophrenia and promote a treatment orientation. METHOD Computer and library-based resources were used to review the literature on depression in schizophrenia ...
S. Siris
semanticscholar   +1 more source

ARE BENZODIAZEPINES ANTIPSYCHOTIC AGENTS ? [PDF]

The Lancet, 1975
Gabriella Ba, Marco Trabucchi
openaire   +3 more sources

Basic Principles in the Use of Antipsychotic Agents

Psychiatric Services, 1973
After 17 years of extensive USC in treating the psychoses, antipsychotic agents are still inappropriately prescribed by psychiatrists and other physicians. To help remedy the situation, the author has compiled a set of clearly defined principles of drug administration.
openaire   +4 more sources

Piperazinylalkyl Heterocycles as Potential Antipsychotic Agents

Journal of Medicinal Chemistry, 1995
We recently reported on a series of pyrrole Mannich bases orally active in inhibiting the conditioned avoidance response (CAR) in rats. These compounds exhibit affinity for both D2 and 5-HT1A receptors, and some are noncataleptogenic. Such a profile suggests that they may be potential antipsychotic agents which lack the propensity for causing ...
Kukla Mj, Bruce E. Maryanoff, Robert E. Boyd, Malcolm K. Scott, Debra J. Bennett, P. S. Blum, E. W. Baxter, E. A. Malloy, E. E. Codd, Cynthia A. Maryanoff   +9 more
openaire   +3 more sources