Results 21 to 30 of about 71,079 (262)

Drug-induced liver injury in association with antipsychotics

European Psychiatry, 2022
Introduction Drug-induced liver injury is one of the leading causes for acute liver failure and drug withdrawal after marketing approval. One important risk factor is the extent of exposure of the hepatocytes to a substance, either by high doses or by ...
R. Zeiss, M. Gahr
doaj   +1 more source

Serum paraoxonase levels of schizophrenia patients treated with typical, atypical and combined antipsychotics

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Schizophrenia is a devastating disorder, starting in early adulthood and continuing with relapses and remissions. Prevalence of schizophrenia is 1% and the life expectancy of these patients is reduced.
Mehmet Akif Camkurt, Mehmet Gunes, Süleyman Demir, Aslihan İbiloglu, Mehmet Cemal Kaya, Mahmut Bulut, Abdullah Atli   +6 more
doaj  

Are antipsychotics carcinogenic?: A review of the literature

European Psychiatry
Introduction Antipsychotics are currently widely prescribed for various mental disorders. A presumption of a potential carcinogenic effect of antipsychotics was raised by certain studies.
S. Walha, D. Mezri, K. Mahfoudh, S. Hamzaoui, A. Ouertani, U. Ouali, A. Aissa, R. Jomli   +7 more
doaj   +1 more source

Characterization of binding of antipsychotics to muscarinic receptors using mouse cerebral cortex

Journal of Pharmacological Sciences, 2019
Antipsychotics are often the first-line treatment for behavioral and psychological symptoms of dementia. However, the potential anticholinergic effects of antipsychotics could counteract the therapeutic effects of cholinesterase inhibitors used to treat ...
Keisuke Obara, Saki Horiguchi, Toma Shimada, Takumi Ikarashi, Fumiko Yamaki, Kazuhiro Matsuo, Takashi Yoshio, Yoshio Tanaka   +7 more
doaj   +1 more source

Antipsychotic combinations for schizophrenia [PDF]

Cochrane Database of Systematic Reviews, 2017
Many people with schizophrenia do not achieve a satisfactory treatment response with their initial antipsychotic drug treatment. Sometimes a second antipsychotic, in combination with the first, is used in these situations.To examine whether:1. treatment with antipsychotic combinations is effective for schizophrenia; and2.
Javier, Ortiz-Orendain, Santiago, Castiello-de Obeso, Luis Enrique, Colunga-Lozano, Yue, Hu, Nicola, Maayan, Clive E, Adams   +5 more
openaire   +4 more sources

Trend in the Utilization of Antipsychotics in the National Health Coverage Era in Indonesia: A Cross-Sectional Study

Borneo Journal of Pharmacy
The utilization pattern of antipsychotics has undergone significant changes since the introduction of atypical antipsychotics. Currently, medication for patients with schizophrenia predominantly uses atypical antipsychotics rather than typical ...
Julaeha Julaeha, Verra Yuliana, Josephine Paramita Ayuningtyas   +2 more
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Asenapine versus other atycipal antipsychotics for schizoaffective disorder Case study

European Psychiatry
Introduction Antipsychotics are psyschotropic medications that are indicated for the treatment of physchosis and mood disorders. Due to minimal side effects and their efficacy (affecting many receptors) compared to standard antipsychotics, today ...
E. Shaska
doaj   +1 more source