Results 221 to 230 of about 46,487 (292)

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1179-1194, May 2026.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Effectiveness of Herbal Medicine Compared to Antidepressants in Patients with Schizophrenia Spectrum Disorders Accompanied by Depression: a systematic review and meta-analysis. [PDF]

J Pharmacopuncture
Kwon CY, Kim MJ, Lee KE, Oh JW, Kim JW, Jeon HL, Lee B, Kim PW, Choi Y.   +8 more
europepmc   +1 more source

Accelerating Generic Long‐Acting Antiretrovirals for Global HIV Treatment: Workshop Findings and a Roadmap to Access

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1195-1204, May 2026.
The global HIV response aims for widespread availability of affordable, quality‐assured long‐acting antiretroviral (LA ARV) drugs to achieve sustained epidemic control, particularly in low‐ and middle‐income countries. This report summarizes key discussion points, findings, and outcomes from an international workshop on generic LA ARVs, held in ...
Usman Arshad, Lobna Gaayeb, Henry Pertinez, Rajith K. R. Rajoli, Melynda Watkins, Parag Nimbolkar, Simone Perazzolo, Bharat Pagi, Annemarie Wensing, Saye Khoo, Marta Boffito, René Holm, Zack Panos, Imelda Mahaka, Francois Venter, Benny Kottiri, Keith W. Crawford, Rodney J. Y. Ho, Polly Clayden, Paul Domanico, Kimberly Struble, Andrew Owen, Charles Flexner   +22 more
wiley   +1 more source

QT-prolonging medications: prevalence of use and associated risks in CKD. [PDF]

Nephrol Dial Transplant
Liabeuf S, Berdougo-Tritz J, Augey L, Laville SM, Mbarek A, Deray G, Massy ZA, Jadoul M.   +7 more
europepmc   +1 more source

Development and Internal Validation of a Machine Learning Model for Predicting Long‐Term Opioid Therapy After Hip Fracture Surgery in Older, Opioid‐Naïve Adults

European Journal of Pain, Volume 30, Issue 5, May 2026.
ABSTRACT Background Long‐term opioid therapy (LTOT) after hip fracture surgery is a common postoperative complication associated with adverse outcomes, yet tools to identify at‐risk patients among opioid‐naïve older adults are lacking. This study aimed to develop and internally validate a parsimonious model to predict LTOT following hip fracture ...
Yasmina Maria Tudorache, Simon Storgaard Jensen, Katie Jane Sheehan, Jan‐Erik Gjertsen, Alma Becic Pedersen   +4 more
wiley   +1 more source

Weight gain under antipsychotic and mood stabilizing treatment: a narrative review about mechanisms and future options. [PDF]

Int J Bipolar Disord
Seiter HT, Fellendorf FT, Popkova D, Reininghaus EZ.   +3 more
europepmc   +1 more source

Racial and Ethnic Representation in Dementia Clinical Trials Registered on ClinicalTrials.gov in the United States, United Kingdom, and Canada

International Journal of Geriatric Psychiatry, Volume 41, Issue 5, May 2026.
ABSTRACT Objective To evaluate racial and ethnic representation and temporal trends in phase II–IV dementia clinical trials conducted in the United States, United Kingdom, and Canada. Methods We interrogated ClinicalTrials.gov for interventional dementia and Alzheimer's disease (AD) trials completed since 2000.
Daniel Kramarczyk, Clive Ballard, Anne Corbett, Miguel Vasconcelos Da Silva, Kamara Israel‐ Mcleish, Jeffrey Cummings, Zunera Khan   +6 more
wiley   +1 more source

Clinical practice guidelines for the management of bipolar disorder: 2025 update. [PDF]

Indian J Psychiatry
Menon V, Ganesh R, Deep R, Sarkhel S, Goswami S, Mohapatra D, Munoli RN, Sharma PSVN, Reddy MS, Muralidharan K.   +9 more
europepmc   +1 more source

Efficacy of Dextromethorphan Augmentation in SSRI‐Resistant Obsessive–Compulsive Disorder: A Randomized Controlled Trial

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Obsessive–compulsive disorder (OCD) is a chronic condition associated with marked functional impairment and high rates of treatment resistance. Converging evidence implicates glutamatergic dysregulation in OCD pathophysiology.
Ahmad Zolghadriha, Afagh Anjomshoaa, Romina Bagheri   +2 more
wiley   +1 more source

Antidepressant Augmentation of Antipsychotic Treatment in Schizophrenia: A Narrative Review. [PDF]

Med Sci Monit
Li W, Gao B, Liu Y, He W, Zha W, Du S, Zeng Y, Zhang Y.   +7 more
europepmc   +1 more source