Results 91 to 100 of about 366,153 (356)

Structure‐Guided Engineering of a Promiscuous O‐Methyltransferase for a SAM Regeneration Biocatalysis Platform of Methylated Pharmaceuticals

Advanced Science, EarlyView.
A substrate promiscuous and regioselective O‐methyltransferase, SmOMT, is functionally and structurally characterized. A double mutant, SmOMTE152A/I306A, exhibited enhanced catalytic activity. By coupling this mutant with a mutant halide methyltransferase, AtHMTV140T, for SAM regeneration, a superior artificial fusion enzyme, AtHMTV140T‐L95‐SmOMTE152A ...
Xiran Xiong, Jun Song, Shihan Li, Lu Jin, Qi He, Baohui Zhang, Yan Cao, Shanyong Yi, Yanfang Yang, Xiang Li, Juan Li, Wei Huang   +11 more
wiley   +1 more source

Saving Renaissance and Reformation: History, Grammar, and Disagreements with the Dead

Religions, 2012
Renaissance and Reformation used to serve historians as the main terms with which to refer to European history from roughly 1300–1600. Today those terms are commonly replaced with early modern history, and the periodization of European history into ...
Constantin Fasolt
doaj   +1 more source

Pan2‐Pan3 Complex‐Mediated Deadenylation Enforces mRNA Quality Control for Infection of the Rice Blast Fungus

Advanced Science, EarlyView.
Discovery that deadenylation, rather than transcription, acts as the rate‐limiting step for developmental timing in a plant pathogen. Evidence that P‐body integrity and mRNA decay are mechanistically coupled to rapid cellular differentiation under environmental stress. Identification of Pan2‐Pan3 as a pathogen‐specific “meta‐virulence factor” absent in
Ziwei Lv, Junting Feng, Shenxian Zhou, Zhiguang Qu, Jun Peng, Xiao‐Lin Chen, Deng Chen   +6 more
wiley   +1 more source

BURIALS OF THE FALLEN IN ANCIENT GREECE

Zbornik radova Filozofskog fakulteta u Splitu, 2021
The paper evaluates works of ancient authors who mention and provide details of the burial of fallen soldiers in ancient Greece, and then it compares them with preserved archaeological finds.
Lucia Nováková
doaj  

Masculinity Studies on Two Continents and in Two Eras: Thomas A. Hickey in Victorian Dublin and Progressive Era America, 1868-1925 [PDF]

, 2014
This project added to a much larger work, a definitive biography of Thomas Aloysius Hickey (1868-1925) in the genre of the “New Biography,” which means by necessity using more than collections of letters, diaries, and writings--work that is attentive to ...
Stanton, Alanna M.
core   +1 more source

Computational universes

, 2005
Suspicions that the world might be some sort of a machine or algorithm existing ``in the mind'' of some symbolic number cruncher have lingered from antiquity. Although popular at times, the most radical forms of this idea never reached mainstream. Modern
Alexandrov, Alexandrov, Alexandrov, Bell, Benacerraf, Bennett, Benz, Bernstein, Bernstein, Borchers, Boskovich, Boyer, Brady, Brauer, Bridgman, Brukner, Calude, Calude, Casti, Casti, Casti, Casti, Chaitin, Chaitin, Chaitin, Chaitin, Conway, Drobot, Dyson, Earman, Eccles, Einstein, Einstein, Elnaschie, Elnaschie, Finkelstein, Fortnow, Fredkin, Fredkin, Fussy, Glauber, Gray, Greenberger, Grünbaum, Gödel, Gödel, Gödel, Herbert, Herzog, Hogarth, Jennewein, Kanter, Karl Svozil, Kochen, Komar, Leff, Lester, Macdonald, Mermin, Meyer, Miller, Moore, Moore, Navara, Peres, Pitowsky, Pitowsky, Pitowsky, Planck, Popper, Putnam, Rado, Redhead, Rössler, Rössler, Rössler, Schaller, Shimony, Specker, Specker, Svozil, Svozil, Svozil, Svozil, Svozil, Svozil, Svozil, Svozil, Svozil, Svozil, Svozil, Svozil, Thomas, Thomson, Toffoli, Toffoli, Ulam, von Neumann, Weyl, Wigner, Wolfram, Wooters, Wright, Wright, Zeilinger, Zeilinger, Zuse, ‘t Hooft   +107 more
core   +5 more sources

Memory, tradition, and Christianization of the Peloponnese [PDF]

, 2015
This work examines the use of memory and tradition in the Christianization of the Peloponnese based on the evidence of the location and topography of churches.
Sweetman, Rebecca Jane
core   +2 more sources

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Etnogeografie a archeologie údolí Jaghnóbu

AntropoWebzin, 2014
The Yaghnob Valley is nowadays considered as (geographically) isolated region; historically the region was not an isolated part of Sogdiana as it was commonly suggested.
Ľubomír Novák
doaj  

Paléohydrographie et archéologie de l'espace en pays tricastin : de l'archéologie aérienne à la télédetection satellitaire

Cybergeo, 1999
The Tricastin region (France - Drôme and Vaucluse Departments) is one of the regions for which the most information on the ancient agrarian structure is available.
Ibtissem Tounsi, Cécile Jung, Jean-François Berger, Gérard Chouquer   +3 more
doaj   +1 more source