Results 101 to 110 of about 236,558 (261)
Nail Surgery in Children: Specific Challenges and Practical Considerations
ABSTRACT Nail surgery in children represents a specific field within dermatologic surgery. Although the procedures themselves are largely similar to those performed in adults, the indications, technical constraints, and perioperative management differ substantially. Pediatric nail disorders are often clinically recognizable, which frequently limits the
F. Lamoline, B. Richert
wiley +1 more source
Introduction: Antiretroviral drugs (ARVs) are associated with the occurrence of adverse drug reactions (ADRs). The Medicines Control Authority of Zimbabwe requires that all ADRs be reported within 15 days of detection.
Godwin Choga +7 more
doaj +1 more source
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Stoichiometric Binding of Cyclophilin‐A to The HIV‐1 Capsid Modulates Its Mechanoelastic Properties
The HIV‐1 capsid is a protein nanocapsule that must balance rigidity and flexibility to enter the cell nucleus. Atomic force microscopy simulations reveal that binding of the host protein Cyclophilin A tunes this mechanical response: partial coverage preserves deformability, while excessive binding induces brittleness and failure.
Juan S. Rey +2 more
wiley +1 more source
Jamil A Al-Mughales1,2 1Department of Clinical Microbiology and Immunology, King Abdul-Aziz University, Jeddah, Kingdom of Saudi Arabia; 2Department of Clinical Laboratories-Diagnostic Immunology Division, King Abdul-Aziz University Hospital, Jeddah ...
Al-Mughales JA
doaj
Molecular glues: Recent advances in cereblon substrate identification and mechanistic insights
Molecular glues exert diverse core biological functions by inducing or stabilizing protein–protein interactions, extending far beyond the traditional scope of targeted protein degradation. Key breakthroughs include expanded cereblon substrate recognition, sustained G protein‐coupled receptor megacomplex signaling, and the first orthosteric molecular ...
Qingyun Guan +5 more
wiley +1 more source
BACKGROUND: No large clinical end-point trials have been conducted comparing regimens among human immunodeficiency virus type 1-positive persons starting antiretroviral therapy.
Cohort, Collaboration +1 more
core
Naturally Occurring ZCCHC3 Variants Modulate Antiretroviral Activity in Cynomolgus Macaques
ABSTRACT Many mammalian cells restrict viral replication by utilizing various host restriction factors. We recently demonstrated that CCHC‐type zinc‐finger‐containing protein 3 (ZCCHC3) suppresses human immunodeficiency virus type 1 (HIV‐1) replication through multiple mechanisms.
Jacob Fadipe +3 more
wiley +1 more source
Can a good death occur for those who balance on the edges of grievability? In Bali, where death marks a transition within the cycles of reincarnation, a good death depends on the mortuary care performed by intimate others – care that may be foreclosed to those whose lives are shaped by stigma.
Sylvia Tidey
wiley +1 more source
Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall +8 more
wiley +1 more source

