Results 101 to 110 of about 236,558 (261)

Nail Surgery in Children: Specific Challenges and Practical Considerations

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Nail surgery in children represents a specific field within dermatologic surgery. Although the procedures themselves are largely similar to those performed in adults, the indications, technical constraints, and perioperative management differ substantially. Pediatric nail disorders are often clinically recognizable, which frequently limits the
F. Lamoline, B. Richert
wiley   +1 more source

Evaluation of Surveillance System for Adverse Drug Reaction Due to Antiretroviral Drugs, Mazowe District, Zimbabwe, 2021

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: Antiretroviral drugs (ARVs) are associated with the occurrence of adverse drug reactions (ADRs). The Medicines Control Authority of Zimbabwe requires that all ADRs be reported within 15 days of detection.
Godwin Choga   +7 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Stoichiometric Binding of Cyclophilin‐A to The HIV‐1 Capsid Modulates Its Mechanoelastic Properties

open access: yesSmall, EarlyView.
The HIV‐1 capsid is a protein nanocapsule that must balance rigidity and flexibility to enter the cell nucleus. Atomic force microscopy simulations reveal that binding of the host protein Cyclophilin A tunes this mechanical response: partial coverage preserves deformability, while excessive binding induces brittleness and failure.
Juan S. Rey   +2 more
wiley   +1 more source

Development and Validation of a Three-Parameter Scoring System for Monitoring HIV/AIDS Patients in Low-Resource Settings Using Hematological Parameters

open access: yesHIV/AIDS: Research and Palliative Care, 2023
Jamil A Al-Mughales1,2 1Department of Clinical Microbiology and Immunology, King Abdul-Aziz University, Jeddah, Kingdom of Saudi Arabia; 2Department of Clinical Laboratories-Diagnostic Immunology Division, King Abdul-Aziz University Hospital, Jeddah ...
Al-Mughales JA
doaj  

Molecular glues: Recent advances in cereblon substrate identification and mechanistic insights

open access: yesSmart Molecules, EarlyView.
Molecular glues exert diverse core biological functions by inducing or stabilizing protein–protein interactions, extending far beyond the traditional scope of targeted protein degradation. Key breakthroughs include expanded cereblon substrate recognition, sustained G protein‐coupled receptor megacomplex signaling, and the first orthosteric molecular ...
Qingyun Guan   +5 more
wiley   +1 more source

Rates of disease progression according to initial highly active antiretroviral therapy regimen: a collaborative analysis of 12 prospective cohort studies

open access: yes, 2006
BACKGROUND: No large clinical end-point trials have been conducted comparing regimens among human immunodeficiency virus type 1-positive persons starting antiretroviral therapy.
Cohort, Collaboration   +1 more
core  

Naturally Occurring ZCCHC3 Variants Modulate Antiretroviral Activity in Cynomolgus Macaques

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT Many mammalian cells restrict viral replication by utilizing various host restriction factors. We recently demonstrated that CCHC‐type zinc‐finger‐containing protein 3 (ZCCHC3) suppresses human immunodeficiency virus type 1 (HIV‐1) replication through multiple mechanisms.
Jacob Fadipe   +3 more
wiley   +1 more source

Mortal relationality: waria family care and the ethics of dying in Bali Relationnalité mortelle : soins familiaux des waria et éthique des mourants à Bali

open access: yesJournal of the Royal Anthropological Institute, EarlyView.
Can a good death occur for those who balance on the edges of grievability? In Bali, where death marks a transition within the cycles of reincarnation, a good death depends on the mortuary care performed by intimate others – care that may be foreclosed to those whose lives are shaped by stigma.
Sylvia Tidey
wiley   +1 more source

Trajectories of medication for opioid use disorder and their impact on HIV testing among people who inject drugs in India: A longitudinal assessment of clinic‐based data

open access: yesAddiction, Volume 120, Issue 4, Page 745-755, April 2025.
Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall   +8 more
wiley   +1 more source

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