Results 141 to 150 of about 236,558 (261)

HIV‐associated nephropathy: A decade of clinical outcomes, global disparities and emerging promise

HIV Medicine, EarlyView.
Abstract Objective To review the pathogenesis, epidemiology, clinical presentation, management and outcomes of HIV‐associated nephropathy (HIVAN), with emphasis on global disparities, genetic susceptibility (APOL1) and emerging therapeutic and technological advances.
Deepak V. Pathiyil, Nicola Wearne, Brendon Price, Frank Post, Dami A. Collier   +4 more
wiley   +1 more source

The Role of Innate Lymphoid Cells in Autoimmune, Allergic and Infectious Diseases: A Systematic Review

Immunology, EarlyView.
This systematic review establishes disease‐specific dysregulations of human innate lymphoid cells (ILCs), demonstrating that an ILC1/ILC3 imbalance compromises mucosal barriers in inflammatory bowel disease, while activated ILC2s drive allergic airway inflammation.
Luan F. Lückmann, Henrique R. Dal‐Pizzol, Louise M. Lückmann, Davi E. Salini, Bruna C. Hasckel, Mikaeli Minati, Bruno Kluwe‐Schiavon, Tatiana Barichello   +7 more
wiley   +1 more source

Linoleic Acid Enhances Murine Natural Killer Cell Function In Vitro but Compromises Mitochondrial Bioenergetic Function During Retroviral Infection

Immunology, EarlyView.
Natural Killer (NK) cells are potent effectors against virus‐infected and tumour cells. During Friend Virus (FV) infection, fatty acid metabolism supports NK‐cell effector functions. Here, we found that NK cells from FV‐infected mice preferentially take up linoleic acid (LA), which reduced proliferation, mitochondrial function, and increased reactive ...
Vaasudevan Sridhar, Simone Schimmer, Tanja Werner, Rachel Giesen, Mohamed Saad, Constantin P. Krempe, Sven W. Meckelmann, Ulf Dittmer, Elisabeth Littwitz‐Salomon   +8 more
wiley   +1 more source

Episodic memory rehabilitation for HIV‐associated neurocognitive disorders: A scoping review

Journal of Neuropsychology, EarlyView.
Abstract Despite extensive research on HIV‐associated neurocognitive disorders (HAND), interest in cognitive rehabilitation has emerged only within the past 15 years. HAND are characterised by mild‐to‐moderate impairments in multiple cognitive domains: attention, episodic memory and executive functions.
Signe Andersen, Sylvane Faure
wiley   +1 more source

Beyond pharmaceutical bandaids: universal access to antiretroviral therapy in Canada. [PDF]

CMAJ
Brisson J, Sheehan N, Lemire B, Monteith K, David PM.   +4 more
europepmc   +1 more source

European Consortium for Lipodystrophies consensus definition and classification framework for monogenic lipodystrophy

Journal of Internal Medicine, EarlyView.
Abstract Lipodystrophy comprises a heterogeneous group of disorders characterized by reduced adipose tissue often associated with severe metabolic complications. Lipodystrophy may be genetic, acquired, or secondary to medical therapies initiated for other conditions.
Robert K. Semple, Martin Wabitsch, Baris Akinci, Saif Alyaarubi, Marjoleine F. Broekema, Rebecca J. Brown, Giovanni Ceccarini, Carolina Cecchetti, Solaf M. Elsayed, Antía Fernández‐Pombo, Alessandra Gambineri, Ingrid M. Jazet, Lotte Kleinendorst, Konstanze Miehle, Elif A. Oral, Flavia Prodam, Ferruccio Santini, David B. Savage, Nadia Shaukat Ali, Ekaterina Sorkina, Magdalena Szopa, Marie‐Christine Vantyghem, Camille Vatier, Corinne Vigouroux, Julia von Schnurbein, David Araújo‐Vilar   +25 more
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Diagnostic Accuracy Studies: Sensitivity, Specificity, and Beyond

Journal of Periodontal Research, EarlyView.
This methodological article covers key diagnostic accuracy measures, common pitfalls in diagnostic accuracy studies, and how evidence should progress from diagnostic accuracy to clinical effectiveness, with examples from various fields. ABSTRACT Diagnostic tests are central to medical care, and their evaluation remains methodologically challenging ...
Nancy Vegas, Lisa Friedlander, Jérémie F. Cohen   +2 more
wiley   +1 more source

Prevalence, high-risk HPV type profile, and factors associated with high-risk HPV infection among women living with HIV in Kinshasa, Democratic Republic of the Congo. [PDF]

Front Public Health
Neze-Sebakunzi J, Doro Altan AM, Ceffa S, Guidotti G, Capparucci S, Ciccacci F, Musikingala M, Nkuba-Ndaye A, Makangara-Cigolo JC, Kisenzele JK, Kabeya-Mampuela T, Orlando S, Ahuka-Mundeke S.   +12 more
europepmc   +1 more source

A Mathematical Model for Estimating the Number of Health Workers Required for Universal Antiretroviral Treatment [PDF]

Despite recent international efforts to increase antiretroviral treatment (ART) coverage, it is estimated that more than 5 million people who need ART in developing countries do not receive such treatment.
Salal Humair, David E. Bloom, Till Bärnighausen   +2 more
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