Results 131 to 140 of about 175,256 (310)

Impact of antiretroviral therapy on renal function among HIV-infected Tanzanian adults: a retrospective cohort study.

PLoS ONE, 2014
BackgroundData regarding the outcomes of HIV-infected adults with baseline renal dysfunction who start antiretroviral therapy are conflicting.MethodsWe followed up a previously-published cohort of HIV-infected adult outpatients in northwest Tanzania who ...
Bonaventura C T Mpondo, Samuel E Kalluvya, Robert N Peck, Rodrick Kabangila, Benson R Kidenya, Lucheri Ephraim, Daniel W Fitzgerald, Jennifer A Downs   +7 more
doaj   +1 more source

Cost Effectiveness Analysis of Clinically Driven versus Routine Laboratory Monitoring of Antiretroviral Therapy in Uganda and Zimbabwe [PDF]

, 2012
BACKGROUND: Despite funding constraints for treatment programmes in Africa, the costs and economic consequences of routine laboratory monitoring for efficacy and toxicity of antiretroviral therapy (ART) have rarely been evaluated.
Amurwon, Jovita, Abdel G. Babiker (158530), Darbyshire Janet, Antonieta Medina Lara (168787), Antonieta Medina Lara, Charles F. Gilks (164480), Munderi Paula, Wakaholi, Barbara Nyanzi, Walker, A Sarah, Babiker, AG, Elly Katabira, Paula Munderi, Reid Andrew, Kasirye, Ronnie, James Hakim, Andrew Reid, Gibb, Diana M., Janet Darbyshire (59117), Jesse Kigozi (168794), Katabira Elly, Gilks, CF, Gilks, Charles F, Kityo Cissy, Darbyshire, J, Jovita Amurwon, Cissy Kityo, Walker A. Sarah, Kigozi, Jesse, Mugyenyi Peter, Barbara Nyanzi Wakaholi, Gibb, DM, Mugyenyi, Peter, Lara, AM, Walker, AS, Muchabaiwa Lazarus, Reid, Andrew, Peter Mugyenyi (168847), Darbyshire, Janet, Diana M. Gibb (164420), Medina Lara Antonieta, Ssali Francis, Kityo, Cissy, Grosskurth Heiner, Grosskurth, Heiner, Abdel G Babiker, Ruben E. Mujica Mota (168817), Kasirye Ronnie, Nyanzi Wakaholi, B, Jesse Kigozi, Walker, Ann, Wakaholi, BN, Team, Ssali, Francis, Ssali, F, Lazarus Muchabaiwa, Medina Lara, Antonieta, Hakim James, Walker, A. Sarah, Peter Mugyenyi, Janet Darbyshire, Gilks, Charles F., Team, DARTT, DART Trial Team, Diana M Gibb, Muchabaiwa, L, Elly Katabira (10701), A Sarah Walker, Kasirye, R, Ronnie Kasirye (168825), Paula Munderi (164469), Katabira, Elly, Muchabaiwa, Lazarus, Munderi, P, Hakim, J, Gibb, Diana M, Barbara Nyanzi Wakaholi (168811), Mota, Ruben E. Mujica, Gilks Charles F., Amurwon Jovita, Jovita Amurwon (168800), James Hakim (164478), Babiker, Abdel G, Amurwon, J, Charles F Gilks, Kityo, C, Nyanzi Wakaholi, Barbara, Babiker, Abdel G., Gibb Diana M., Mota, REM, Cissy Kityo (168842), Mujica Mota, Ruben E, Heiner Grosskurth (37057), Ruben E Mujica Mota, Reid, A, Medina-Lara, A, Kigozi Jesse, Francis Ssali, Mujica Mota Ruben E., Andrew Reid (168831), A. Sarah Walker (145609), Heiner Grosskurth, Lara, Antonieta Medina, Katabira, E, Ronnie Kasirye, Munderi, Paula, Grosskurth, H, Hakim, James, Francis Ssali (158549), Mujica-Mota, Ruben, Lazarus Muchabaiwa (168805), Kigozi, J, Mugyenyi, P, Nyanzi Wakaholi Barbara, Babiker Abdel G.   +113 more
core   +1 more source

HIV‐1 viral load and reservoir size remain stable following SARS‐CoV‐2 mRNA vaccination in people with HIV

HIV Medicine, EarlyView.
Abstract Background The potent immunogenicity of mRNA vaccination raised concerns about its impact on HIV‐1 viral load (VL) and reservoir size in people with HIV, which could drive vaccine hesitancy. As part of a prospective clinical trial, we investigated whether SARS‐CoV‐2 mRNA vaccination induced changes in VL and reservoir size after a 1‐year three‐
Oscar Kieri, Bianca B Jütte, Jan Vesterbacka, Soo Aleman, Hans‐Gustaf Ljunggren, Marcus Buggert, J Peter Svensson, Anders Sönnerborg, Piotr Nowak   +8 more
wiley   +1 more source

Longitudinal changes in plasma biomarkers of immune activation, neuronal inflammation and injury in persons with HIV initiating ART

HIV Medicine, EarlyView.
Abstract Background Data on changes in biomarkers of brain health, and their associations with cognitive function in adults commencing either dual‐ or triple‐antiretroviral therapy (ART) are sparse. Methods Plasma biomarkers (neurofilament light [NfL], glial fibrillary acidic protein [GFAP], sCD14, CXCL10, neopterin and IL‐6) were measured at baseline ...
Merle Henderson, Peter Dutey‐Magni, Carolina Herrera, Wolfgang Stöhr, Alejandro Arenas‐Pinto, Owen Swann, Amanda Heslegrave, Henrik Zetterberg, John Tregoning, Sarah Fidler, François Raffi, Andrea Calcagno, Ab Babiker, Alan Winston   +13 more
wiley   +1 more source

Factors associated with different responses to combination antiretroviral therapy in an observational cohort study of HIV-1 infected patients [PDF]

, 2008
The introduction of combination antiretroviral therapy (cART) into clinical practice for the treatment of HIV in 1995-1996 has led to dramatic reductions in mortality and morbidity. Factors linked to a positive response to therapy include a potent and
Bannister, W.P., Bannister, W P
core  

Efficacy of dolutegravir/lamivudine in adults with HIV‐1 and isolated reactive hepatitis B core antibody: Insights from Phase 3/3b study results

HIV Medicine, EarlyView.
Abstract Objectives As two‐drug HIV‐1 antiretroviral therapy (ART) regimens become standard, data gaps remain concerning their safety and efficacy among people with isolated reactive hepatitis B core antibodies (anti‐HBc). Here, we assessed the safety and efficacy of dolutegravir/lamivudine (DTG/3TC) versus three‐ or four‐drug regimens (3DRs/4DRs ...
D. Fox, J. Slim, E. T. Overton, A. Doblado‐Maldonado, P. Jeffery, R. A. Grove, S. D. Advani, R. Borsi, C. M. Parry, M. Underwood, B. Jones   +10 more
wiley   +1 more source

Comparative 10-year atherosclerotic cardiovascular disease risk in Ethiopian HIV patients on first-line versus second-line combined antiretroviral therapy

Atherosclerosis Plus
Background: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of morbidity and mortality in HIV patients, but the impact of combined antiretroviral therapy regimens on its risk in Ethiopia is unclear. This study assessed the 10-year ASCVD
Balew Arega, Gashaw Solela, Tariku Fekadu, Tirhas Tadesse, Bekele Alemayehu, Amanuel Zeleke, Kidat Ayele   +6 more
doaj   +1 more source

Systematic screening for age‐related comorbidities: Health care optimization among persons with HIV in an outpatient setting

HIV Medicine, EarlyView.
Abstract Background Age‐related comorbidities occur earlier and more frequently in people with HIV (PWH) than in the general population and have emerged as a key challenge in long‐term HIV care. Unfortunately, many of these conditions remain undiagnosed, and systematic screening in clinical practice remains limited.
Anna Katrine Haslund Roed, Anne‐Mette Lebech, Sabine Singh, Ole Kirk, Susanne Dam Nielsen   +4 more
wiley   +1 more source

Do people with HIV really have the choice between oral and injectable ART? Evidence from a multicentric survey in the Swiss HIV cohort study

HIV Medicine, EarlyView.
Abstract Introduction Injectable long‐acting antiretroviral therapy (iLA‐ART) offers a valuable alternative to oral ART (oART). While the efficacy of these treatment strategies is similar, adequate information on their specific characteristics is essential to enable people with HIV (PWH) to decide which option best suits their values and preferences ...
Yonas Martin, Bernard Surial, Martin Müller, Lukas Baumann, David Jackson‐Perry, David Haerry, Marie Ballif, Charles Béguelin, Miriam Bürgi, Aline Munting, Matthias Cavassini, Dominique Braun, Andri Rauch, Reto Auer, Gilles Wandeler, the Swiss HIV Cohort Study   +15 more
wiley   +1 more source

Mortality trends for diabetes mellitus, hypertension and cardiovascular disease among people living with and without HIV in Brazil during the COVID‐19 pandemic, 2020–2022

HIV Medicine, EarlyView.
Abstract Introduction People living with HIV (PLWH) face an increasing burden of non‐AIDS‐related chronic conditions. However, how the COVID‐19 pandemic affected chronic disease‐related mortality in this population remains unclear. We assessed changes in mortality among PLWH in Brazil during the COVID‐19 pandemic.
Tatyellen Natasha da Costa Oliveira, Rodrigo C. Moreira, Luiz Max Carvalho, Flávio Codeço Coelho, Marcelo Ferreira da Costa Gomes, Leonardo S. Bastos, Laís Picinini Freitas, Antonio G. Pacheco   +7 more
wiley   +1 more source