Antirheumatic agents - Open Access .click

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Diabetes-Modifying Antirheumatic Drugs: The Roles of DMARDs as Glucose-Lowering Agents [PDF]

Medicina, 2022
Systemic inflammation represents a shared pathophysiological mechanism which underlies the frequent clinical associations among chronic inflammatory rheumatic diseases (CIRDs), insulin resistance, type 2 diabetes (T2D), and chronic diabetes complications,
Marco Infante +6 more
doaj +3 more sources

Studies on antirheumatic agents. 3-Benzoylpropionic acid derivatives.

Chemical and Pharmaceutical Bulletin, 1988
As part of the search for new antirheumatic agents, three types of 3-benzoylpropionic acid derivatives having a mercapto moiety in their structures were prepared, and tested for suppressing activity on adjuvant arthritis in Sprague-Dawley rats. A structure-activity relationship study showed that substitution on the phenyl ring contributed to the ...
K, Kameo +5 more
semanticscholar +5 more sources

Comparative Risk of Alzheimer Disease and Related Dementia Among Medicare Beneficiaries With Rheumatoid Arthritis Treated With Targeted Disease-Modifying Antirheumatic Agents [PDF]

JAMA Network Open, 2022
Key Points Question Is use of targeted disease-modifying antirheumatic drugs associated with risk of Alzheimer disease and related dementia (ADRD)? Findings In this cohort study including 22 569 propensity score–matched patient pairs, initiation of ...
Rishi Desai +9 more
openalex +2 more sources

Thyroid Autoimmunity and Function after Treatment with Biological Antirheumatic Agents in Rheumatoid Arthritis [PDF]

Frontiers in Endocrinology, 2017
With the increased pro-inflammatory response in both rheumatoid arthritis and thyroid autoimmune diseases, treatment with biological antirheumatic agents (BAAs) of the former may affect the course of the latter.
Sofie Bliddal +2 more
openalex +2 more sources

Effects of antirheumatic agents on cytokines [PDF]

Seminars in Arthritis and Rheumatism, 1996
A review of the literature concerning the effects of traditional antirheumatic drugs on cytokines and the cytokine and anticytokine approaches already used in the therapy of rheumatoid arthritis (RA) is presented. Many antirheumatic drugs are capable of cytokine modulation in vitro. Corticosteroids inhibit the transcription of a broad spectrum of genes
Barrera Rico, P. +3 more
openaire +5 more sources

Antirheumatic agents in covid-19: is IL-6 the right target? [PDF]

Annals of the Rheumatic Diseases, 2020
The letter of Monti et al 1 on covid-19 in patients with chronic arthritis treated with immunosuppressive therapies stimulates some considerations. The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infects cells through the ACE-2 receptor,
Pier Leopoldo Capecchi +12 more
openalex +2 more sources

2012 Update of the 2008 American College of Rheumatology recommendations for the use of disease‐modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis [PDF]