Results 131 to 140 of about 59,908 (306)

Molecular bases and role of viruses in the human microbiome. [PDF]

open access: yes, 2014
Viruses are dependent biological entities that interact with the genetic material of most cells on the planet, including the trillions within the human microbiome.
Abeles, Shira R, Pride, David T
core   +1 more source

Genome‐wide interaction screen for Mycobacterium tuberculosis ClpCP protease reveals toxin–antitoxin systems as a major substrate class

open access: yesThe FEBS Journal, 2020
In Mycobacterium tuberculosis (Mtb), the Clp protease degradation pathway, mediated by the modular ClpCP and ClpXP protease complexes, is essential for growth and presents an attractive drug target.
Michal Ziemski   +4 more
semanticscholar   +1 more source

Crystal Structure and Functional Characterization of YjgK From Salmonella Typhimurium

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 93, Issue 11, Page 1935-1943, November 2025.
ABSTRACT The YhcH/YjgK/YiaL (DUF386) family, widely conserved across bacterial species, is involved in essential cellular processes yet remains poorly characterized. YjgK from Salmonella enterica serovar Typhimurium has drawn attention because of its potential role in biofilm formation associated with metal homeostasis, which may be critical for ...
Su‐Yeon Choi   +6 more
wiley   +1 more source

Operator-Theoretic Characterization of Eventually Monotone Systems

open access: yes, 2017
Monotone systems are dynamical systems whose solutions preserve a partial order in the initial condition for all positive times. It stands to reason that some systems may preserve a partial order only after some initial transient.
Mauroy, Alexandre, Sootla, Aivar
core   +1 more source

The Immunizing Effects of Antitoxin [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1895
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openaire   +3 more sources

Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system

open access: yesNucleic Acids Research, 2020
The two-gene module HEPN/MNT is predicted to be the most abundant toxin/antitoxin (TA) system in prokaryotes. However, its physiological function and neutralization mechanism remains obscure.
Jianyun Yao   +10 more
semanticscholar   +1 more source

Wolbachia Host Shifts and Widespread Occurrence of Reproductive Manipulation Loci in European Butterflies

open access: yesMolecular Ecology, Volume 34, Issue 21, November 2025.
ABSTRACT Wolbachia is the most frequent bacterial endosymbiont of arthropods and nematodes. Although it is mostly vertically transmitted, from parent to offspring through the egg cytoplasm, horizontal transfer of Wolbachia is thought to be common over evolutionary timescales.
Eric Toro‐Delgado   +5 more
wiley   +1 more source

Structural insights into chaperone addiction of toxin-antitoxin systems

open access: yesNature Communications, 2019
SecB homologs can be associated with stress-responsive type II toxin–antitoxin (TA) systems and form tripartite toxin-antitoxin-chaperone systems (TAC).
Valérie Guillet   +12 more
doaj   +1 more source

TADB 2.0: an updated database of bacterial type II toxin–antitoxin loci

open access: yesNucleic Acids Res., 2017
TADB2.0 (http://bioinfo-mml.sjtu.edu.cn/TADB2/) is an updated database that provides comprehensive information about bacterial type II toxin–antitoxin (TA) loci. Compared with the previous version, the database refined and the new data schema is employed.
Y. Xie   +7 more
semanticscholar   +1 more source

VapC21 Toxin Contributes to Drug-Tolerance and Interacts With Non-cognate VapB32 Antitoxin in Mycobacterium tuberculosis

open access: yesFrontiers in Microbiology, 2020
The prokaryotic ubiquitous Toxin-antitoxin (TA) modules encodes for a stable toxin and an unstable antitoxin. VapBC subfamily is the most abundant Type II TA system in M. tuberculosis genome.
Arun Sharma   +9 more
semanticscholar   +1 more source

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