Results 201 to 210 of about 23,589 (259)
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Thiophene containing triarylmethanes as antitubercular agents
Bioorganic & Medicinal Chemistry Letters, 2008A new series of thiophene containing triarylmethane derivatives were synthesized from the Friedel-Crafts alkylation of diarylcarbinols followed by incorporation of amino alkyl chains. These were evaluated against Mycobacterium tuberculosis H37R(v) and showed the activity in the range of 3.12-12.5 microg/mL in vitro.
Maloy Kumar, Parai +4 more
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New Hydroxamic Acids as Antitubercular Agents
Nature, 1952PREVIOUSLY, one of us suggested using salicylhydroxamic acid as an antitubercular agent1. The substance was subjected to clinical examination by another of us (S.H.) and showed promising results in fifteen cases of pulmonary tuberculosis. The substance was well tolerated by the patients, when large doses of 10–20 gm./day were administered.
T, URBANSKI +3 more
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Synthesis and Investigation of Phthalazinones as Antitubercular Agents
Chemistry – An Asian Journal, 2019AbstractA series of 2‐ and 7‐substituted phthalazinones was synthesised and their potential as anti‐tubercular drugs assessed via Mycobacterium tuberculosis (mc26230) growth inhibition assays. All phthalazinones tested showed growth inhibitory activity (MIC <100 μm), and those compounds containing lipophilic and electron‐withdrawing groups generally
Kristiana T. Santoso +5 more
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Therapeutische Umschau. Revue therapeutique, 2000
The personally experienced development of chemotherapy for tuberculosis during the last half century represents some highlights of new knowledges and practical successes: the discovery of antituberculosis drugs; the comprehension of their actions and side effects; the exploration of mechanisms of resistance against antituberculosis agents; the ...
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The personally experienced development of chemotherapy for tuberculosis during the last half century represents some highlights of new knowledges and practical successes: the discovery of antituberculosis drugs; the comprehension of their actions and side effects; the exploration of mechanisms of resistance against antituberculosis agents; the ...
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Antitubercular agents are medications used to treat tuberculosis (TB), a serious infectious disease caused by Mycobacterium tuberculosis. These agents are categorized into first-line and second-line drugs based on their efficacy, toxicity, and role in TB treatment regimens. First-line antitubercular drugs, such as isoniazid, rifampin, pyrazinamide, and
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[Oral desensitization to antitubercular agents].
Revue de pneumologie clinique, 1997We report a case of hypersensitivity reaction to majors antituberculosis drugs. We have successfully performed oral desensitization to "Rifater *". We present our protocol that we compare to those proposed in the literature.
I, Drira +4 more
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Molecular imaging in oncology: Current impact and future directions
Ca-A Cancer Journal for Clinicians, 2022Steven P Rowe, Martin G Pomper
exaly
Piperazine in Antitubercular Agents
Tüberküloz, Mycobacterium tuberculosis basilinin sebep olduğu öldürücü, bulaşıcı bir hastalıktır. Çoklu ilaca dirençli tüberküloz suşlarının ortaya çıkması hastalığın tedavisini zorlaştırmıştır. Bu nedenle ilaç direncinin üstesinden gelebilecek ve düşük yan etkili güçlü antitüberküler bileşiklerin geliştirilmesi acil bir ihtiyaçtır. Piperazin, iki adetZengin, Merve +2 more
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Treatment of muscle‐invasive and advanced bladder cancer in 2020
Ca-A Cancer Journal for Clinicians, 2020Vaibhav G Patel +2 more
exaly