Results 41 to 50 of about 15,987 (189)

The antral follicle: a microenvironment for oocyte differentiation

The International Journal of Developmental Biology, 2012
Mammalian reproduction hinges upon the timely ovulation of a fully differentiated oocyte. This event is the culmination of a complex and dynamic developmental relationship between the oocyte and the antral follicle housing it; the antral follicle constitutes a specialized microenvironment or niche, uniquely suited to the needs of the oocyte as it ...
Margo L, Hennet, Catherine M H, Combelles   +1 more
openaire   +3 more sources

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source

Knockout of RNA Binding Protein MSI2 Impairs Follicle Development in the Mouse Ovary: Characterization of MSI1 and MSI2 during Folliculogenesis

Biomolecules, 2015
Characterizing the mechanisms underlying follicle development in the ovary is crucial to understanding female fertility and is an area of increasing research interest.
Jessie M. Sutherland, Alexander P. Sobinoff, Kara M. Gunter, Barbara A. Fraser, Victoria Pye, Ilana R. Bernstein, Evan Boon, Nicole A. Siddall, Luisa I. De Andres, Gary R. Hime, Janet E. Holt, Thomas Graf, Eileen A. McLaughlin   +12 more
doaj   +1 more source

Identification of A p300–SP1–BRD4 Transcriptional Axis as a Key Driver of AR Hyperactivation in Polycystic Ovarian Syndrome

Advanced Science, EarlyView.
This study reveals a pivotal epigenetic regulatory role for the histone acetyltransferase p300, demonstrating that its acetylation of histone 3 at lysine 18 and 27 (H3K18ac and H3K27ac), alongside the formation of the p300/BRD4/SP1 complex, drives AR activation and ovarian fibrosis in PCOS.
Zhengquan Zhu, Yihan Wang, Haiyun Chen, Xinye Yu, Tingyu Wang, Yajing Weng, Meihong Guo, Ying Huang, Gaojian Tao, Wangsen Cao, Yong Wang, Daojuan Wang   +11 more
wiley   +1 more source

High physical activity and ovarian reserve: a prospective study of normo-ovulatory professional athletes

Journal of Ovarian Research, 2022
Background This study investigated whether high physical activity affects ovarian reserve in normo-ovulatory, reproductive-age women. Methods This prospective, observational study compared 31 professional female athletes, with 31 women who did not engage
Netanella Miller, Yael Pasternak, Einat Haikin Herzberger, Hadar Gluska, Chen Dorenstein, Roni Rahav, Rina Hemi, Nahid Zada, Amir Wiser   +8 more
doaj   +1 more source

Development of antral follicles after xenografting of isolated small human preantral follicles

Reproductive BioMedicine Online, 2008
Small human pre-antral follicles can be enzymatically isolated from the surrounding stroma, and are able to survive after 7 days of xenografting. The aim of the present study was to assess the developmental capacity of enzymatically isolated human follicles after long-term xenografting to severe combined immunodeficient (SCID) mice.
Marie-Madeleine, Dolmans, Wu Yuan, Yuan, Alessandra, Camboni, Antoine, Torre, Anne, Van Langendonckt, Belen, Martinez-Madrid, Jacques, Donnez   +6 more
openaire   +2 more sources

Follicle-stimulating hormone responsiveness in antral follicles from aryl hydrocarbon receptor knockout mice [PDF]

Reproductive Biology and Endocrinology, 2013
Abstract Background Previous studies have demonstrated that pre-pubertal aryl hydrocarbon receptor knockout (AHRKO) mice have slow antral follicle growth and reduced capacity to produce estradiol compared to wild-type (WT) mice.
Hernández-Ochoa, Isabel, Gao, Liying, Peretz, Jackye, Basavarajappa, Mallikarjuna S, Bunting, Stacey L, Karman, Bethany N, Paulose, Tessie, Flaws, Jodi A   +7 more
openaire   +2 more sources

Real‐Time and High‐Resolution NIR‐II‐L Imaging of Netrin‐1‐Mediated Neurovascular Coupling Driven by Dose‐Dependent Electroacupuncture

Advanced Science, EarlyView.
Disrupted neurovascular coupling contributes to ovarian dysfunction in polycystic ovary syndrome. Using near‑infrared II long‑wavelength imaging, this study visualizes how electroacupuncture dynamically regulates ovarian blood vessels in vivo. Immediate and cumulative stimulation elicit distinct vascular responses via a Netrin‐1 dependent mechanism ...
Yicong Wang, Zi‐Han Chen, Jiajia Li, Wei Hu, Ying Cao, Yu Wang, Xiaoyu Tong, Wenhan Lu, Yuze Yang, Yuehao Wang, Yan Xiao, Wenhao Gao, Yuning Chen, Yuyan Hou, Fan Zhang, Yi Feng   +15 more
wiley   +1 more source

Color Doppler analysis of female reproductive vasculature in Behçet’s disease

Reumatismo, 2016
Behçet’s disease (BD) may affect female reproductive vasculature. We aimed to evaluate Doppler sonographic characteristics of female reproductive vasculature and also ovarian volume, endometrial thickness (EMT) and antral follicle count of BD patients in
M.E. Tezcan, O. Temizkan, A. Ozderya, M. Melikoglu, K. Aydin, M. Sargin, S. Temizkan   +6 more
doaj   +1 more source

A lower antral follicle count is associated with infertility [PDF]

Fertility and Sterility, 2011
To determine whether infertile women have lower antral follicle counts (AFC) than age-matched normal women.Case-control.Academic center.A total of 881 infertile women and 771 women from the community.Antral follicle count and basal hormone measurements.Median AFCs and FSH levels were compared between the two groups within 5-year age strata by using the
Mitchell P, Rosen, Erica, Johnstone, Carolyne, Addauan-Andersen, Marcelle I, Cedars   +3 more
openaire   +2 more sources