Results 81 to 90 of about 15,987 (189)

Nanomotor‐Driven Extracellular Vesicles With Effective Tissue Penetration for Targeted Therapy of Primary Ovarian Insufficiency

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
ABSTRACT Stem cells and their derived extracellular vesicles (EVs) offer hope for functional reconstruction and fertility in premature ovarian insufficiency (POI) caused by gonadotoxic drugs. However, the clinical application of EVs is impeded by their instability, limited tissue penetration, and lack of targeted delivery to ovarian injury sites. Here,
Yaoqin Mu, Jiachen Wu, Mingwei Lv, Xinyi Zhang, Yinhua Song, Jihui Ai, Ding Ma, Kezhen Li   +7 more
wiley   +1 more source

Transcription Factor TCF12‐Mediated Maternal Gene Expressions in Mouse Oocyte Are Prerequisites of Successful Fertilisation and Zygotic Genome Activation

Cell Proliferation, Volume 59, Issue 3, March 2026.
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao, Chi Zhang, Zuo‐Qi Deng, Yue‐xin Qiu, Zhao Zhang, Heng‐Yu Fan, Jing Li, Hong‐Bo Wu   +7 more
wiley   +1 more source

Ovarian influence on circadian and infradian modulation of nicotine‐seeking in female mice

Journal of Neuroendocrinology, Volume 38, Issue 3, March 2026.
Abstract Sex differences in tobacco intake are closely associated with hormonal fluctuations during the menstrual cycle in women. Elevated estrogen levels have been associated with increased stress, which may lead to a higher likelihood of seeking psychoactive substances.
Zenaida Rosas‐Ovando, Gisela Aguirre, Tania Molina‐Jiménez, Mónica Flores‐Muñoz, Óscar López‐Franco, Rossana C. Zepeda, Aleph A. Corona‐Morales, Armando Jesús Martínez, Roberto C. Salgado‐Delgado, Claudia Juárez‐Portilla   +9 more
wiley   +1 more source

Consequences of eight consecutive applications of equine chorionic gonadotropin on ovarian follicle development and ovulation in bos indicus cows

Ciência Rural
: The equine chorionic gonadotropin (eCG) is a glycoprotein produced in mare endometrial calices. In bovine, it is used in estrus synchronization protocols.
Bhárbara Delboni Stuhr, Isaac Santos Gil, Tracy Ferreira Lacerda, Mauricio Gomes Favoreto, Bárbara Loureiro   +4 more
doaj   +1 more source

Fetal Bovine Serum Is Essential for Maintaining Viability of Porcine Blastocysts During Extended In Vitro Culture: A Comparative Study With Defined Supplements

Reproduction in Domestic Animals, Volume 61, Issue 3, March 2026.
ABSTRACT Extended in vitro culture (EIVC) of porcine embryos beyond Day 7 is critical for understanding peri‐implantation development but remains technically challenging due to the rapid degeneration of blastocysts. While defined serum‐free supplements, such as B27 and growth factor cocktails (FGF2, LIF, IGF1; FLI), have successfully supported EIVC in ...
Seongju Lee, Il‐Jeoung Yu, Yubyeol Jeon   +2 more
wiley   +1 more source

FSH Requirements for Follicle Growth During Controlled Ovarian Stimulation

Frontiers in Endocrinology, 2019
Introduction: Ovarian follicle growth is a key step in the success of assisted reproductive treatment, but limited data exists to directly relate follicle growth to recombinant FSH (rFSH) dose.
Ali Abbara, Aaran Patel, Tia Hunjan, Sophie A. Clarke, Germaine Chia, Pei Chia Eng, Maria Phylactou, Alexander N. Comninos, Stuart Lavery, Geoffrey H. Trew, Rehan Salim, Raj S. Rai, Tom W. Kelsey, Waljit S. Dhillo   +13 more
doaj   +1 more source

Anti-mullerian hormone and antral follicle count as predictors of ovarian response in assisted reproduction

Journal of Human Reproductive Sciences, 2013
Objective: The objective of this study was to test the hypothesis that AMH and antral follicle count (AFC) are good predictors of ovarian response to controlled ovarian stimulation and to compare them.
Y Himabindu, M Sriharibabu, K K Gopinathan, Usha Satish, T Fessy Louis, Parasuram Gopinath   +5 more
doaj   +1 more source

Transcriptome profiling of the theca interna in transition from small to large antral ovarian follicles.

PLoS ONE, 2014
The theca interna layer of the ovarian follicle forms during the antral stage of follicle development and lies adjacent to and directly outside the follicular basal lamina. It supplies androgens and communicates with the granulosa cells and the oocyte by
Nicholas Hatzirodos, Katja Hummitzsch, Helen F Irving-Rodgers, Raymond J Rodgers   +3 more
doaj   +1 more source

Follicle development as an orchestrated signaling network in a 3D organoid

Journal of Biological Engineering, 2019
The ovarian follicle is the structural and functional unit of the ovary, composed of the female gamete (the oocyte) and supportive somatic cells. Follicles are not only the source of a female’s germ cell supply, but also secrete important hormones ...
Andrea S. K. Jones, Ariella Shikanov
doaj   +1 more source

Histological Effects of Letrozole and Clomiphene Citrate on Albino Rat Ovary after Consecutive 1-4 Estrous Cycles

Journal of Rawalpindi Medical College, 2017
Background:To observe the histological effects of letrozole and Clomiphene citrate on albino rat  ovary after consecutive 1-4 estrous cycles. Methods: An experimental study was carried out on eighty four adult female Albino rats. The rats were equally
Fauzia Qureshi
doaj