Results 141 to 150 of about 634,616 (387)

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou   +30 more
wiley   +1 more source

Programmable and Reversible 3D‐to‐3D Shape Transformation: Hierarchical Multimodal Morphing Based on Liquid Crystal Elastomers

open access: yesAdvanced Science, EarlyView.
Hierarchical multimodal 3D‐to‐3D shape morphing is achieved in liquid crystal elastomer‐elastomer bilayers via programmable mismatch strains. Combining pre‐stretch and thermal actuation enables reversible transformations with non‐zero Gaussian curvature, empowering over 30 complex configurations for biomimetic camouflage, adaptive robotics, and dynamic
Jiayu Tian   +4 more
wiley   +1 more source

A Swarm intelligence approach for biometrics verification and identification [PDF]

open access: yes, 2012
In this paper we investigate a swarm intelligence classification approach for both biometrics verification and identification problems. We model the problem by representing biometric templates as ants, grouped in colonies representing the clients of a
Pulina, Luca
core  

Multiscale Cell–Cell Interactive Spatial Transcriptomics Analysis

open access: yesAdvanced Science, EarlyView.
In this study, we present the MultiScale Cell‐Cell Interactive Spatial Transcriptomics Analysis method, which unites the strengths of spatially resolved deep learning techniques with a topological representation of multi‐scale cell‐cell similarity relations.
Sean Cottrell, Guo‐Wei Wei
wiley   +1 more source

Utilizing Proteolytic‐Resistant Nano‐Short Peptide Based on Naphthyl Tail‐Anchored to Combat Bacterial Infections

open access: yesAdvanced Science, EarlyView.
Antimicrobial peptides (AMPs) show potential as alternatives to antibiotics for bacterial infections; however, their susceptibility to proteases limits wider application. In this study, N4 nanofibers are constructed by integrating anti‐enzymolysis motif into the self‐assembly system triggered by naphthyl‐anchored.
Xi Yan   +6 more
wiley   +1 more source

Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail‐Eating Snake

open access: yesAdvanced Science, EarlyView.
Dietary adaptation studies from a holobiome perspective are scarce beyond mammals. This research reveals how genomic and microbial interactions drive dietary specialization in the Mengla snail‐eating snake, with evidence of gut symbiont convergence between reptiles and mammals.
Chaochao Yan   +10 more
wiley   +1 more source

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