CD44 in Group 1 Innate Lymphoid Cells Impacts the Development and Progression of Steatohepatitis [PDF]
Liver International, Volume 45, Issue 9, September 2025.ABSTRACT Background and Aims Innate lymphoid cells (ILCs) play pivotal roles in inflammation and fibrosis, which are key features of chronic liver diseases. The contribution of group 1 ILCs, including natural killer (NK) cells and helper‐like ILC1s, to liver inflammation during steatohepatitis and metabolic dysfunction‐associated steatotic liver ...
Manon Bourinet +20 more
wiley +2 more sources
Rheumatology, 2011 Celem badania była ocena wczesnej skuteczności leczenia anty-TNFu chorych na zesztywniające zapalenie stawów kręgosłupa (ZZSK).Badaniem objęto 34 osoby (10 kobiet i 24 mężczyzn w wieku średnio39 lat), chorych na aktywną postać ZZSK, zakwalifikowanych ...
Artur Bachta +3 more
doaj +1 more source
Changes in expression of TNF alpha and its receptors mRNAs in oocytes and granulosa cells in mice with experimental immune ovarian failure [PDF]
, 2014 Purpose: To investigate the expression of TNF- α and its receptors (types I and II) at mRNA level in oocytes and granulose cells as well as to study effect of TNF-α on follicular cell death in mice with experimental immune ovarian failure induced by ...
Grushka, Nataliya +4 more
core +1 more source
Parasite genetic diversity does not influence TNF-mediated effects on the virulence of primary rodent malaria infections [PDF]
, 2006 The pro-inflammatory cytokine tumour necrosis factor alpha (TNF-alpha) is associated with malaria virulence (disease severity) in both rodents and humans.
Long, G H +19 more
core +1 more source
Response to combination therapy with interferon alfa-2a and ribavirin in chronic hepatitis C according to a TNF-alpha promoter polymorphism [PDF]
, 2003 Background. Tumor necrosis factor-alpha (TNF-alpha) is involved in the pathogenesis of chronic active hepatitis C. Polymorphisms in the promoter region of the TNF-alpha gene can alter the TNF-alpha expression and modify the host immune response.
Konig, A. +8 more
core +1 more source
Disease Markers, Volume 2018, Issue 1, 2018., 2018 Background. Alterations of the small‐intestinal permeability (s‐IP) might play an essential role in a subgroup of diarrhoea‐predominant IBS (D‐IBS) patients. Goals. (a) To analyse in D‐IBS patients the symptom profile in relation to the altered (+) or not (−) s‐IP using the Gastrointestinal Symptom Rating Scale (GSRS).
Francesco Russo +7 more
wiley +1 more source
, 2023 TNF-α production by PBMCs from 3 donors cultured on films synthesised from 3 batches of each optimal treatment type (180°C for 1.5h or NaOH for 2h) versus native chitosan for 24 hours. Symbols are grouped based on the batch of chitosan films made.
Sophie Louise Reay (13288635)
core +1 more source
TNF-?, cukrzyca typu 1 i limfocyty T regulatorowe [PDF]
Pediatric Endocrinology, Diabetes and Metabolism, 2010 W badaniach na modelach zwierzęcych cukrzycy typu 1 (DM1), a także na ludzkich komórkach regulatorowych wykazano, że TNF-? upośledza zdolność tych komórek do hamowania choroby. Podanie myszom NOD TNF-? zmniejszało odsetek limfocytów Treg, z kolei terapia
Monika Ryba, Jolanta Myśliwska
doaj
Modulation of autocrine TNF-α-stimulated matrix metalloproteinase 9 (MMP-9) expression by mitogenactivated protein kinases in THP-1 monocytic cells [PDF]
, 2006 Matrix metalloproteinase 9 (MMP-9) is implicated in various physiological processes by its ability to degrade the extracellular matrix (ECM) and process multiple regulatory proteins. Normally, MMP-9 expression is tightly controlled in cells. Sustained or
Helmut Kolb +9 more
core +1 more source
Synergistic and antagonistic effects of TNF-[alpha] and IGF-I in heart failure : "in vitro" and "in vivo" study of cardiac and skeletal muscle [PDF]
, 2006 Cardiovascular diseases are a major cause of morbidity and mortality in industrialized countries. All forms of myocardial injury first lead to compensatory hypertrophy, which eventually progresses to heart failure.
Murigande, Claire
core +1 more source