Results 111 to 120 of about 150,161 (341)

Mitochondria‐Targeting Abasic Site‐Reactive Probe (mTAP) Enables the Manipulation of Mitochondrial DNA Levels

open access: yesAngewandte Chemie International Edition, Accepted Article.
Mitochondrial DNA (mtDNA) encodes essential genes for mitochondrial and cellular functions and acts as a cell signaling molecule in innate immune and inflammatory responses. Defects in mtDNA are implicated in a range of mitochondrial disorders and human diseases. Currently, no chemical strategy exists to prevent mtDNA loss under genotoxic stress.
Anal Jana, Yu-Hsuan Chen, Linlin Zhao
wiley   +1 more source

SAFE LOCKER – A SECURE CARGO TRANSPORT CONTROL SUPPORT IT SYSTEM

open access: yesTASK Quarterly, 2019
The article presents the assumptions and architectural implementation of a cargo transport control support system, as well as the preliminary results of tests of the operation of this system in environmental conditions identical with the conditions of ...
ARTUR ANUS, PAWEŁ BUCHWALD
doaj   +1 more source

Building a Bridge Between Ambient MS and LC‐MS by Non‐Exhaustive Microdesorption

open access: yesAngewandte Chemie International Edition, Accepted Article.
Ambient mass spectrometry (AMS) offers rapid screening but faces challenges in analyzing complex samples due to high matrix effects and limited selectivity. The absence of a separation step can also lead to false positives due to the isomers or isobars.
Wei Zhou, Janusz Pawliszyn
wiley   +1 more source

Photoresponsive slide‐ring gels enable modulation of sliding dynamics

open access: yesAngewandte Chemie International Edition, Accepted Article.
Cyclodextrin‐based slide‐ring gels (SRG) have emerged as a promising class of materials owing to their unique topology. Upon mechanical loading, the slidable cross‐links of the polymer network freely translocate along the polymer backbone enabling pronounced energy dissipation in the material, which is associated with exceptional ductility and ...
Dalila Cafagno   +3 more
wiley   +1 more source

A description of the early life history stages of the kob, Argyrosomus hololepidotus (Pisces: Sciaenidae), from southern Africa [PDF]

open access: yes, 1990
The larval development of the kob, Argyrosomus hololepidotus is described and illustrated from a series of specimens collected in Algoa Bay, South Africa.
Beckley, L.E.
core   +2 more sources

PCR‐Free Site‐Directed Mutagenesis on Repetitive Sequences Using Single‐Stranded DNA‐Assisted Double‐Stranded DNA Nicking by DNAzymes

open access: yesAngewandte Chemie International Edition, Accepted Article.
Site‐directed mutagenesis (SDM) is a key driver for many biochemical investigations and biotechnological applications. Despite decades of development, it is still difficult to perform SDM on some sequences, including highly repetitive ones, because polymerase chain reaction (PCR) is often used as the most effective method for SDM, but results in ...
Mingkuan Lyu   +3 more
wiley   +1 more source

Long non-coding RNAs: New biomarkers for prognosis and diagnosis of colon cancer

open access: yesTumor Biology, 2017
Dysregulation of long non-coding RNAs has been found in many human cancers, including colorectal cancer that is still the third most prevalent cancer worldwide and related to poor prognosis; along with this, robust testimony has identified that long non ...
Heng Deng   +7 more
doaj   +1 more source

The Cystic Sponge Anus

open access: yesCase Reports in Dermatology
<b><i>Introduction:</i></b> A peculiar spongy appearance of the perianal skin was observed in a patient who underwent wide excision surgery for inguinal and gluteal hidradenitis suppurativa (HS). <b><i>Case Presentation:</i></b> This peculiar appearance was observed in a 62-year-old male patient.
Van Der Zee, Hessel H., Aarts, Pim
openaire   +4 more sources

Home - About - Disclaimer - Privacy