Results 211 to 220 of about 58,847 (249)

Imperforate Anus

, 1966
William B. Kiesewetter
openalex   +2 more sources

Design and Synthesis of Tetrahydropyrrolo[3,4‐c]Pyrazole Sigma‐1 Receptor Ligands

ChemMedChem, EarlyView.
This study highlights the tetrahydropyrrolo[3,4‐c]pyrazole scaffold as a promising platform for S1R ligands development. Key findings include compound 19’s high S1R affinity (Ki=75 nM), influenced by strategic nitrogen substitutions and reduced steric hindrance.
Giuseppe Cosentino, Maria Dichiara, Giuliana Costanzo, Alessandro Coco, Lorella Pasquinucci, Agostino Marrazzo, Antonio Rescifina, Emanuele Amata   +7 more
wiley   +1 more source

Microbiome and Colorectal Cancer in Humans: A Review of Recent Studies. [PDF]

J Anus Rectum Colon
Takamaru H, Tsay C, Shiba S, Yachida S, Saito Y.   +4 more
europepmc   +1 more source

Congenital Malformations of the Rectum, Anus, and Genito-urinary tracts

, 1964
F. Douglas Stephens, Reginald Webster
openalex   +1 more source

Bulky Ligands for Open Channels: Manganese (II) sql MOFs from Pyridyl‐Functionalised [3]Polynorbornanes

ChemPlusChem, EarlyView.
Two new [n]polynorbornane based ligands (LMe and LEt) form isoreticular sql MOFs with crystal structure analysis revealing neatly aligned nets creating large accessible 1D channels with a distinct lack of interpenetration. The ester moieties of these ligands orient into the channels highlighting potential of these ligands for the construction of MOFs ...
William Murrell, Pavel M. Usov, Carol Hua, Fred Pfeffer   +3 more
wiley   +1 more source

Cross-Reactivity: a Case of Paracetamol-Induced Generalized Bullous Fixed Drug Eruption Followed by Dipyrone-Induced Fixed Drug Eruption. [PDF]

Clin Cosmet Investig Dermatol
Wang Y, Xue H, Dai H, Yang L.
europepmc   +1 more source

Cancer of the Colon, Rectum and Anus

, 1966
C. Edward Floyd, Carl T. Stirling, Isidore Cohn   +2 more
openalex   +2 more sources

High‐Throughput Drug Derivatization and Bioassay by Desorption Electrospray Ionization Mass Spectrometry

ChemPlusChem, Accepted Article.
Adapting high‐throughput (HT) synthetic methods to the modification of drugs and to testing of their bioactivity should expedite drug discovery. Here, we demonstrate the applicability of HT desorption electrospray ionization mass spectrometry (DESI MS) to achieve late‐stage functionalization (LSF) and so to rapidly generate a modified opioid library ...
R Graham Cooks, Jyotirmoy Ghosh, Nicolás M. Morato, Yunfei Feng   +3 more
wiley   +1 more source

Impact of SGLT2 inhibitors on survival in gastrointestinal cancer patients undergoing chemotherapy and/or radiotherapy: a real-world data retrospective cohort study. [PDF]

BMC Cancer
Flausino LE, Carrasco AGM, Furuya TK, Tuan WJ, Chammas R.   +4 more
europepmc   +1 more source

Corporate Social Responsibility (CSR) Decoupling and Tax Avoidance: Symbolic Use of Sustainable Boards in the European Union?

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study explores the relationship between corporate social responsibility (CSR) decoupling and tax avoidance, as well as the moderating effect of sustainable boards on this relationship. Based on agency and legitimacy theories, we used panel data of listed firms headquartered in the European Union (2076 firm‐year observations) in the 2017 ...
Patrick Velte
wiley   +1 more source