Results 41 to 50 of about 80,007 (305)

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

open access: yesAdvanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma   +10 more
wiley   +1 more source

Second trimester diagnosis of imperforate anus

open access: yes, 2015
Imperforate anus or anorectal atresia is often associated with major fetal structural defects but it may also be an isolated abnormality. Prenatal diagnosis is difficult but may be assisted by ultrasound detection of enterolithiasis in dilated bowel and ...
Ksiaa, A.   +9 more
core   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

open access: yesAdvanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu   +10 more
wiley   +1 more source

Hidradenoma Papilliferum of the Anus: A Report of 2 Cases and Review of the Literature [PDF]

open access: yesAnnals of Coloproctology, 2019
Hidradenoma papilliferum is a rare benign cystic tumor that originates from apocrine glands or anogenital mammary glands. Here, we describe 2 cases of hidradenoma papilliferum of the anus. Two female patients aged 39 and 35 presented with perianal masses
Guh Jung Seo   +3 more
doaj   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

open access: yesAdvanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi   +12 more
wiley   +1 more source

IMPERFORATE ANUS. [PDF]

open access: yesThe Lancet
n ...
openaire   +1 more source

Three Cases of Imperforate Anus with Recto-urethral Fistula.

open access: yes, 1965
Three Cases of agenesis of the anus with recto-urethral fistula were reported. The first case was a 6-year-old boy with stenosis of the anus. One week after birth he underwent a plastic operation of the anus owing to agensis of the anus with recto ...
高田, 義人   +7 more
core   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

open access: yesAdvanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang   +11 more
wiley   +1 more source

Is screening for anal squamous intraepithelial lesions in women with genital human papillomavirus intraepithelial lesions necessary?

open access: yesDST, 2022
Introduction: There seems to be a fairly close relationship between genital and anal lesions associated with human papillomavirus (HPV) and with the pathogenesis of malignancies in such sites.
Francisco Eugênio de Vasconcelos Filho   +4 more
doaj  

SAFE LOCKER – A SECURE CARGO TRANSPORT CONTROL SUPPORT IT SYSTEM

open access: yesTASK Quarterly, 2019
The article presents the assumptions and architectural implementation of a cargo transport control support system, as well as the preliminary results of tests of the operation of this system in environmental conditions identical with the conditions of ...
ARTUR ANUS, PAWEŁ BUCHWALD
doaj   +1 more source

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