Results 71 to 80 of about 58,847 (249)
Late anastomotic complication after laparoscopic surgery for clinical stage I low rectal cancers located within 5 cm of the anal verge: Sub‐analysis of the ultimate trial
Annals of Gastroenterological Surgery, EarlyView.Anastomotic stenosis and late fistula formation frequently emerge as secondary consequences of early AL, and represent significant complications linked to permanent stoma creation, often proving resistant to treatment. Intestinal prolapse is a characteristic anastomotic complication of ISR that can be caused by excessive intestinal mobilization.Manabu Shimomura, Masanori Yoshimitsu, Yuichiro Tsukada, Hideki Ohdan, Jun Watanabe, Yosuke Fukunaga, Yasumitsu Hirano, Kazuhiro Sakamoto, Hiroki Hamamoto, Hisanaga Horie, Nobuhisa Matsuhashi, Yoshiaki Kuriu, Shuntaro Nagai, Madoka Hamada, Shinichi Yoshioka, Shinobu Ohnuma, Tamuro Hayama, Koki Otsuka, Yusuke Inoue, Kazuki Ueda, Yuji Toiyama, Satoshi Maruyama, Shigeki Yamaguchi, Keitaro Tanaka, Motoko Suzuki, Toshihiro Misumi, Takeshi Naitoh, Masahiko Watanabe, Masaaki Ito, Ultimate Trial Group +29 morewiley +1 more sourceShort‐term outcomes of intracorporeal anastomosis in laparoscopic colectomy for colon cancer: A nationwide, multi‐institutional cohort study in Japan (ICAN study)
Annals of Gastroenterological Surgery, EarlyView.We retrospectively compared intracorporeal and extracorporeal anastomosis in patients undergoing laparoscopic colectomy for colon cancer in 46 institutions by using propensity‐score matching. Intracorporeal anastomosis showed advantages over extracorporeal anastomosis in terms of blood loss, intraoperative vascular injury, bowel recovery, and length of Tomohiro Yamaguchi, Keitaro Tanaka, Jun Watanabe, Hiroki Hamamoto, Atsushi Nishimura, Fumihiko Fujita, Hirokazu Suwa, Masaaki Ito, Kazushige Kawai, Junichiro Hiro, Seiichiro Yamamoto, Sho Nambara, Masato Ota, Yuri Ito, Junji Okuda, Masafumi Inomata, Masahiko Watanabe, Takeshi Naitoh, ICAN Collaborative Study Group of the Japan Society of Laparoscopic Colorectal Surgery, T. Akiyoshi, T. Mukai, Y. Suwa, K. Ikeda, S. Natsume, G. Inaguma, H. Ozawa, R. Nakanishi, K. Kobayashi, T. Hirokawa, A. Nomura, T. Okada, S. Inamoto, Y. Todate, T. Miyakawa, R. Inada, H. Takahashi, T. Suzuki, M. Miguchi, H. Kayano, S. Suzuki, A. Furutani, N. Higashino, R. Makizumi, K. Okabayashi, K. Shigeta, J. Kawamura, T. Wada, K. Hida, Y. Umemoto, M. Numata, K. Kazama, K. Maeda, T. Fukuoka, M. Hotchi, H. Kobayashi, H. Matsumoto, S. Honma, S. Sano, S. Takahashi, Y. Ohno, A. Kanazawa, E. Otsuji, T. Arita, H. Bando, S. Terai, M. Wakabayashi, M. Hosaka, T. Manabe, K. Okuyama, T. Fukuda, S. Mukai, T. Nitta, M. Ishii, T. Akagi, Y. Kinugasa, M. Sasaki, T. Kobatake, R. Ochiai, S. Mori, K. Baba, M. Naito, R. Oshima, K. Uehara, Y. Murata, H. Nagano, S. Tomochika, S. Ohnuma, T. Ono, D. Yoshida, F. Motoi, S. Okazaki, M. Takatsuki, T. Kinjo +92 morewiley +1 more sourceImpact of body mass index as a continuous variable on short‐ and long‐term outcomes in patients undergoing laparoscopic surgery for colon cancer
Annals of Gastroenterological Surgery, EarlyView.Three‐year relapse‐free survival was possibly better in severe obese patients (BMI ≥28.5 kg/m2) who underwent laparoscopic surgery for colon cancer. It suggests that the prognosis of highly obese colorectal cancer patients follow the obesity paradox. Abstract Background
The impact of obesity on colon cancer remains unclear.Takayuki Aiba, Tomonori Akagi, Hidefumi Shiroshita, Kentaro Nakajima, Tetsuji Ohyama, Tatsuya Kinjo, Akiyoshi Kanazawa, Nobuaki Suzuki, Takuya Tokunaga, Manabu Yamamoto, Nobuki Ichikawa, Shungo Endo, Yutaka Kojima, Takatoshi Nakamura, Shuji Saito, Yoshinori Kagawa, Shinobu Ohnuma, Seiichiro Yamamoto, Takeshi Naitoh, Masafumi Inomata +19 morewiley +1 more sourceCurrent updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management
Cancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022 Abstract
Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome Khaled S. Allemailem, Mohammed A Alsahli, Ahmad Almatroudi, Faris Alrumaihi, Fahd Khaleefah Alkhaleefah, Arshad Husain Rahmani, Amjad Ali Khan +6 morewiley +1 more sourceClinical significance of preoperative Glasgow prognostic score in patients with colorectal cancer and synchronous peritoneal metastases
Annals of Gastroenterological Surgery, EarlyView.Preoperative GPS2 is an independent poor prognostic factor in patients with colorectal cancer and synchronous peritoneal metastases, and surgical resection does not improve prognosis in patients with GPS2. Preoperative GPSs may be used as indicators for surgical resection of synchronous peritoneal metastases.Kosuke Fujimoto, Fumikazu Koyama, Hirotoshi Kobayashi, Kenjiro Kotake, Masayasu Kawasaki, Yukihide Kanemitsu, Yusuke Kinugasa, Hideki Ueno, Kotaro Maeda, Takeshi Suto, Michio Itabashi, Kimihiko Funahashi, Heita Ozawa, Shingo Noura, Hideyuki Ishida, Masayuki Ohue, Tomomichi Kiyomatsu, Soichiro Ishihara, Keiji Koda, Hideo Baba, Kenji Kawada, Yojiro Hashiguchi, Takanori Goi, Yuji Toiyama, Naohiro Tomita, Eiji Sunami, Fumihiko Fujita, Jun Watanabe, Kenichi Hakamada, Goro Nakayama, Kenichi Sugihara, Yoichi Ajioka +31 morewiley +1 more sourceSintilimab versus docetaxel as second‐line treatment in advanced or metastatic squamous non‐small‐cell lung cancer: an open‐label, randomized controlled phase 3 trial (ORIENT‐3)
Cancer Communications, Volume 42, Issue 12, Page 1314-1330, December 2022., 2022 Abstract Background
Treatment options for Chinese patients with locally advanced or metastatic squamous‐cell non‐small‐cell lung cancer (sqNSCLC) after failure of first‐line chemotherapy are limited. This study (ORIENT‐3) aimed to evaluate the efficacy and safety of sintilimab versus docetaxel as second‐line treatment in patients with locally advanced ...Yuankai Shi, Lin Wu, Xinmin Yu, Puyuan Xing, Yan Wang, Jianying Zhou, Airong Wang, Jianhua Shi, Yi Hu, Ziping Wang, Guangyu An, Yong Fang, Sanyuan Sun, Caicun Zhou, Changli Wang, Feng Ye, Xingya Li, Junye Wang, Mengzhao Wang, Yunpeng Liu, Yanqiu Zhao, Ying Yuan, Jifeng Feng, Zhendong Chen, Jindong Shi, Tao Sun, Gang Wu, Yongqian Shu, Qisen Guo, Yi Zhang, Yong Song, Shucai Zhang, Yuan Chen, Wei Li, Hongrui Niu, Wenwei Hu, Lijun Wang, Jianan Huang, Yang Zhang, Ying Cheng, Zhengdong Wu, Bo Peng, Jiya Sun, Christoph Mancao, Yanqi Wang, Luyao Sun +45 morewiley +1 more sourceNutritional benefits of pancreas‐sparing total duodenectomy for severe duodenal polyposis in patients with familial adenomatous polyposis
Annals of Gastroenterological Surgery, EarlyView.The postoperative nutritional status of patients with familial adenomatous polyposis who underwent pancreas‐sparing total duodenectomy was better than that of patients who underwent pancreaticoduodenectomy. This study provides the first direct comparison of postoperative nutritional outcomes between patients with pancreas‐sparing total duodenectomy and Ibuki Fujinuma, Toshiro Ogura, Ayano Takahashi, Satoshi Nomura, Kei Kitamura, Amane Takahashi, Takehiro Shiraishi, Yoshiko Mori, Toru Ishiguro, Takatoshi Matsuyama, Youichi Kumagai, Hideyuki Ishida +11 morewiley +1 more sourcePrognosis prediction of stage IV colorectal cancer patients by mRNA transcriptional profile
Cancer Medicine, Volume 11, Issue 24, Page 4900-4912, December 2022., 2022 This study aimed to clarify the prognostic factors for stage IV CRC patients undergoing primary cancer resection but not liver metastasis resection. WES and RNA‐Seq were used to sequence primary cancer tissues of 78 and 84 patients, respectively. Models were established to stratify the prognosis and to predict individual patient prognosis.Bian Wu, Jinwei Yang, Zhiwei Qin, Hongping Yang, Jingyi Shao, Yun Shang +5 morewiley +1 more source