Results 71 to 80 of about 58,847 (249)

Late anastomotic complication after laparoscopic surgery for clinical stage I low rectal cancers located within 5 cm of the anal verge: Sub‐analysis of the ultimate trial

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Anastomotic stenosis and late fistula formation frequently emerge as secondary consequences of early AL, and represent significant complications linked to permanent stoma creation, often proving resistant to treatment. Intestinal prolapse is a characteristic anastomotic complication of ISR that can be caused by excessive intestinal mobilization.
Manabu Shimomura   +29 more
wiley   +1 more source

Short‐term outcomes of intracorporeal anastomosis in laparoscopic colectomy for colon cancer: A nationwide, multi‐institutional cohort study in Japan (ICAN study)

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
We retrospectively compared intracorporeal and extracorporeal anastomosis in patients undergoing laparoscopic colectomy for colon cancer in 46 institutions by using propensity‐score matching. Intracorporeal anastomosis showed advantages over extracorporeal anastomosis in terms of blood loss, intraoperative vascular injury, bowel recovery, and length of
Tomohiro Yamaguchi   +92 more
wiley   +1 more source

Impact of body mass index as a continuous variable on short‐ and long‐term outcomes in patients undergoing laparoscopic surgery for colon cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Three‐year relapse‐free survival was possibly better in severe obese patients (BMI ≥28.5 kg/m2) who underwent laparoscopic surgery for colon cancer. It suggests that the prognosis of highly obese colorectal cancer patients follow the obesity paradox. Abstract Background The impact of obesity on colon cancer remains unclear.
Takayuki Aiba   +19 more
wiley   +1 more source

Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management

open access: yesCancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022
Abstract Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome
Khaled S. Allemailem   +6 more
wiley   +1 more source

Clinical significance of preoperative Glasgow prognostic score in patients with colorectal cancer and synchronous peritoneal metastases

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Preoperative GPS2 is an independent poor prognostic factor in patients with colorectal cancer and synchronous peritoneal metastases, and surgical resection does not improve prognosis in patients with GPS2. Preoperative GPSs may be used as indicators for surgical resection of synchronous peritoneal metastases.
Kosuke Fujimoto   +31 more
wiley   +1 more source

Sintilimab versus docetaxel as second‐line treatment in advanced or metastatic squamous non‐small‐cell lung cancer: an open‐label, randomized controlled phase 3 trial (ORIENT‐3)

open access: yesCancer Communications, Volume 42, Issue 12, Page 1314-1330, December 2022., 2022
Abstract Background Treatment options for Chinese patients with locally advanced or metastatic squamous‐cell non‐small‐cell lung cancer (sqNSCLC) after failure of first‐line chemotherapy are limited. This study (ORIENT‐3) aimed to evaluate the efficacy and safety of sintilimab versus docetaxel as second‐line treatment in patients with locally advanced ...
Yuankai Shi   +45 more
wiley   +1 more source

Nutritional benefits of pancreas‐sparing total duodenectomy for severe duodenal polyposis in patients with familial adenomatous polyposis

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The postoperative nutritional status of patients with familial adenomatous polyposis who underwent pancreas‐sparing total duodenectomy was better than that of patients who underwent pancreaticoduodenectomy. This study provides the first direct comparison of postoperative nutritional outcomes between patients with pancreas‐sparing total duodenectomy and
Ibuki Fujinuma   +11 more
wiley   +1 more source

Interview with the World Class Authorities Frontiers of Cancer Research: An exclusive interview with Professor Luis Diaz

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This is the second installment in the series, “The Interview with the World‐Class Authorities.” We are honored to welcome Prof. Luis Diaz, the Director of the Division of Solid Tumor Oncology at Memorial Sloan Kettering Cancer Center and Editor‐in‐Chief of Cancer Discovery. Prof.
Haruna Takeda   +4 more
wiley   +1 more source

Prognosis prediction of stage IV colorectal cancer patients by mRNA transcriptional profile

open access: yesCancer Medicine, Volume 11, Issue 24, Page 4900-4912, December 2022., 2022
This study aimed to clarify the prognostic factors for stage IV CRC patients undergoing primary cancer resection but not liver metastasis resection. WES and RNA‐Seq were used to sequence primary cancer tissues of 78 and 84 patients, respectively. Models were established to stratify the prognosis and to predict individual patient prognosis.
Bian Wu   +5 more
wiley   +1 more source

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