Results 171 to 180 of about 12,749 (324)

Validation of data quality in the Swedish quality register of gynecologic cancer for cervical cancer and vulvar cancer—a Swedish gynecologic cancer group (Swe‐GCG) study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
The aim of this study was to evaluate the quality of data in the Swedish Quality Register of Gynecologic Cancer (SQRGC on cervical cancer and vulvar cancer in terms of completeness, timeliness, comparability, and validity according to the International Agency for Research on Cancer methodology.
Maria Bjurberg, Kristina Hellman, Tim A. Säll, Christian Staf, Christer Borgfeldt, Erik Holmberg, Jenny Jönsson, Gabriel Lindahl, Angelique Flöter Rådestad, Camilla Sköld, Katja Stenström Bohlin, Karin Stålberg, Elisabeth Åvall‐Lundqvist, Preben Kjølhede, Pernilla Dahm‐Kähler   +14 more
wiley   +1 more source

Effectiveness and Safety of Upadacitinib Induction Therapy for 223 Patients With Crohn's Disease: A GETAID Multicentre Cohort Study

Alimentary Pharmacology &Therapeutics, Volume 61, Issue 10, Page 1662-1670, May 2025.
In a real‐world cohort of 223 highly refractory Crohn's disease patients, upadacitinib induction resulted in a clinical response in about two‐thirds of patients and in steroid‐free clinical remission in half of the patients, with an acceptable safety profile at week 12. ABSTRACT Background Real‐world effectiveness and safety of upadacitinib in patients
Nicolas Richard, Aurélien Amiot, Philippe Seksik, Romain Altwegg, David Laharie, Lucine Vuitton, Maria Nachury, Guillaume Bouguen, Stéphane Nancey, Cyrielle Gilletta, Cléa Rouilon, Benoît Coffin, Matthieu Allez, Anthony Buisson, Catherine Le Berre, Mathieu Uzzan, Ludovic Caillo, Anne‐Laure Pelletier, Laurent Peyrin‐Biroulet, Mathurin Fumery, GETAID, Marianne Hupé, Vered Abitbol, Mathias Vidon, Felix Goutorbe, Morgane Amil, Hedia Brixi, Alban Benezech, Sandy Kwiatek   +28 more
wiley   +1 more source

Colon‐targeted complement C5a1 receptor inhibition using pH‐sensitive nanoparticles ameliorates experimental colitis

British Journal of Pharmacology, EarlyView.
Background and Purpose The complement system is associated with inflammatory bowel disease (IBD) pathology. Complement activation induces C5a production, which signals through the C5a1 receptor (C5aR1) to drive inflammatory responses that may underlie IBD.
Cedric S. Cui, Titaya Lerskiatiphanich, Xaria X. Li, Rabina Giri, Ning Liu, Vinod Kumar, Andrew K. Whittaker, Felicity Y. Han, Richard J. Clark, Jakob Begun, John D. Lee, Trent M. Woodruff   +11 more
wiley   +1 more source

Identification of clinicopathological‐specific driver gene and genetic subtyping of colorectal cancer

Cancer Science, Volume 116, Issue 4, Page 1068-1081, April 2025.
This study analyzed targeted sequencing of 6530 patients with metastatic Chinese colorectal cancer (CRC), identifying 36 novel driver genes with subgroup‐specific implications, such as ERBB4 affecting only male CRC patient outcomes. Additionally, the study utilized network‐based stratification to categorize microsatellite stable (MSS) and unstable (MSI)
Jianjiong Li, Chunnian Wang, Changshun Yang, Hua Bao, Ningyou Li, Xianqiang Huang, Wei Gong, Xinyue Hong, Jiani C. Yin, Jiaohui Pang, Meifu Gan, Danping Yuan   +11 more
wiley   +1 more source

Gastrointestinal stromal tumors (GIST): Role of the surgeon in the molecular medicine era Tumores del estroma gastrointestinal (GIST): papel del cirujano en la era de la medicina molecular

Iatreia, 2010
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Juan Pablo Toro Vásquez, Jorge Alberto Madrid Vélez   +1 more
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Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Engineering Intervertebral Disc Regeneration: Biomaterials, Cell Sources and Animal Models

Cell Proliferation, EarlyView.
This review highlights the current tissue engineering approaches utilising biomaterials, animal models and cell sources for intervertebral disc regeneration and discusses future opportunities. ABSTRACT Intervertebral disc (IVD) degeneration is an age‐related problem triggering chronic spinal issues, such as low back pain and IVD herniation.
Sidong Yang, Farhad Soheilmoghaddam, Peter Pivonka, Joan Li, Samuel Rudd, Trifanny Yeo, Ji Tu, Yibo Zhu, Justin J. Cooper‐White   +8 more
wiley   +1 more source

Anogenital papillomatosis associated with a novel papillomavirus in a grey-headed flying fox. [PDF]

J Vet Diagn Invest
Munday JS, Brown SE, Kay EE, Valenza LD.
europepmc   +1 more source

Mucosal polyposis syndrome mimicking a rectal tumour

ANZ Journal of Surgery, EarlyView.
Wei Ming Ong, Dhaval Joshi, Suat Chin Ng
wiley   +1 more source

Intratumoural tigilanol tiglate in the multicentre treatment of equine sarcoids and cutaneous melanomas

Equine Veterinary Journal, EarlyView.
Abstract Background Intralesional chemotherapeutic administration represents an important treatment option for equine cutaneous neoplasia. Tigilanol‐tiglate (TT), a novel molecule extracted from Fontainea picrosperma, an Australian rainforest plant, is registered for intratumoural treatment of canine MCT, leading to rapid oncosis and tumour slough ...
Raphael Labens, Corey Saba, Jarred Williams, Anna Hollis, Jos Ensink, Eduard Jose‐Cunilleras, Mireia Jordana‐Garcia, Kerstin Bergvall, Mick Ruppin, Frank Condon, Caroline Spelta, Yvonne Elce, Thomas De Ridder, John Morton, Cassandra McGee, Paul Reddell   +15 more
wiley   +1 more source