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Neurobiology of the Orexin System and Its Potential Role in the Regulation of Hedonic Tone
Orexin peptides comprise two neuropeptides, orexin A and orexin B, that bind two G-protein coupled receptors (GPCRs), orexin receptor 1 (OXR1) and orexin receptor 2 (OXR2).
Martin A. Katzman, Matthew P. Katzman
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The development of clinical practice guidelines for social anxiety disorder began in March 2018 when the Joint Clinical Practice Guideline Development Committee for Anxiety and Obsessive–Compulsive Disorders was formed by the Japanese Society of Anxiety ...
Satoshi Asakura+7 more
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(Reprinted and permission from Lancet 2016; 388: 3048-59).
Michelle G, Craske, Murray B, Stein
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Background Patients with severe mental illness (SMI) and comorbid physical conditions were often associated with higher risks of mortality and hospital readmission.
Xiao Wei Tan+6 more
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Plain English summary Adverse childhood experiences (ACEs), such as abuse, are considered a significant public health crisis and are associated with mental and physical health problems later in life.
Renee D. Rienecke+7 more
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Predicting Fear Extinction in Posttraumatic Stress Disorder
Fear extinction is the basis of exposure therapies for posttraumatic stress disorder (PTSD), but half of patients do not improve. Predicting fear extinction in individuals with PTSD may inform personalized exposure therapy development.
Michael W. Lewis+5 more
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Transforming Trauma through an Arts Festival: A Psychosocial Case Study
Through a psychosocial lens, informed by relational psychoanalysis, this article discusses the design, delivery, and impact of The Big Anxiety’s 2022 festival in Warwick, Queensland—an arts-based program that engages with lived experiences of trauma ...
Jill Bennett+4 more
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Background Childhood maltreatment may contribute to brain alterations in posttraumatic stress disorder (PTSD). We previously found that PTSD was associated with white matter compromise, or lower fractional anisotropy (FA), in the left inferior ...
Elizabeth A. Olson+5 more
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Introduction Trauma reexperiencing is dominated by recollection of sensory‐perceptual elements of the trauma, pointing to involvement of the sensory thalamus.
Emily J. Casteen+4 more
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Background: Eye movement desensitization and reprocessing (EMDR) therapy is a treatment meant to reduce vividness and emotionality of distressing memories.
Suzy J.M.A. Matthijssen+4 more
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