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Neurobiology of the Orexin System and Its Potential Role in the Regulation of Hedonic Tone
Brain Sciences, 2022 Orexin peptides comprise two neuropeptides, orexin A and orexin B, that bind two G-protein coupled receptors (GPCRs), orexin receptor 1 (OXR1) and orexin receptor 2 (OXR2).
Martin A. Katzman, Matthew P. Katzman
doaj +1 more source
Neuropsychopharmacology Reports, 2023 The development of clinical practice guidelines for social anxiety disorder began in March 2018 when the Joint Clinical Practice Guideline Development Committee for Anxiety and Obsessive–Compulsive Disorders was formed by the Japanese Society of Anxiety ...
Satoshi Asakura +7 more
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JAMA pediatrics, 2021 Importance Emerging research suggests that the global prevalence of child and adolescent mental illness has increased considerably during COVID-19.
N. Racine +5 more
semanticscholar +1 more source
European Psychiatry, 2021 IntroductionThere are different clinical forms combining anxiety and depression and it is essential to identify them because they will require different management. Among these clinical forms, there is that including anxiety as a symptom within the depressive episode: the anxious depression.ObjectivesThe objective is to find the characteristics of this
Tahmazov, E. +3 more
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Anxiety profiles and protective factors: A latent profile analysis in children [PDF]
Personality and Individual Differences, 124, 201-208 (2018), 2021 The current study investigated the presence of different anxiety profiles in schoolchildren in order to understand whether Mathematics and Test Anxiety are a manifestation of a general form of anxiety, or the expression of specific forms of anxiety. Moreover, we also examined the influence of personal protective factors. The results of a latent profile
arxiv +1 more source
The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022 Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee +16 more
wiley +1 more source
The Lancet, 2016 (Reprinted and permission ...
Michelle G, Craske, Murray B, Stein
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BMC Psychiatry, 2022 Background Patients with severe mental illness (SMI) and comorbid physical conditions were often associated with higher risks of mortality and hospital readmission.
Xiao Wei Tan +6 more
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Predicting Fear Extinction in Posttraumatic Stress Disorder
Brain Sciences, 2023 Fear extinction is the basis of exposure therapies for posttraumatic stress disorder (PTSD), but half of patients do not improve. Predicting fear extinction in individuals with PTSD may inform personalized exposure therapy development.
Michael W. Lewis +5 more
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Journal of Eating Disorders, 2022 Plain English summary Adverse childhood experiences (ACEs), such as abuse, are considered a significant public health crisis and are associated with mental and physical health problems later in life.
Renee D. Rienecke +7 more
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