Results 121 to 130 of about 1,225,873 (314)
Advanced Science, EarlyView.We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong +8 more
wiley +1 more source
The Effect of Exercise on Anxiety of Adolescents with Intellectual Disability
Physical Treatments, 2015 Purpose: The present study aimed to investigate the effect of exercise on the anxiety of adolescents with intellectual disability. Methods: Study method was quasi-experimental with pretest-posttest design and a control group.
Masoomeh Salehpoor +2 more
doaj
Advanced Science, EarlyView.A bioactive hydrogel incorporating Chlorella vulgaris and paeoniflorin within a carboxymethyl chitosan/sodium alginate matrix cross‐linked with genipin is developed for inflammatory bowel disease therapy. The hydrogel exhibits gastric stability and intestine‐responsive release.
Jing Lu +8 more
wiley +1 more source
A comparison of the effects of lorazepam with those of propranolol on experimentally‐induced anxiety and performance. [PDF]
, 1985 SE File, RG Lister
openalex +1 more source
Chemistry Anxiety Among Bachelor-Level Students in Science Education
, 2023 Paras Mani Ghimire
openalex +2 more sources
Advanced Science, EarlyView.Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi +15 more
wiley +1 more source
Do 5HT1B/1D Receptor Agonists have an Effect on Mood and Anxiety Disorders? [PDF]
, 2007 Nicola Morelli +6 more
openalex +1 more source
Advanced Science, EarlyView.Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia +4 more
wiley +1 more source
Helping our Children with Homework: Homework as an Activity of Anxiety for First Generation Bilingual Korean American Mothers [PDF]
, 2012 Hyeyoon Park, Brinda Jegatheesan
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Advanced Science, EarlyView.This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon +21 more
wiley +1 more source