Results 231 to 240 of about 3,732,219 (359)

Enhanced Protein Synthesis and Hippocampus‐Dependent Memory via Inhibition of YTHDF2‐Mediated m6A mRNA Degradation

open access: yesAdvanced Science, EarlyView.
YTHDF2‐mediated m6A mRNA decay critically regulates learning and memory. Its forebrain‐specific knockout in mice impedes degradation of m6A‐modified mRNAs, enhancing hippocampal synaptic transmission, protein synthesis, and memory. Conversely, hippocampal YTHDF2 reintroduction or SEMA4B reduction reverses this enhancement, while its overexpression ...
Kuan Li   +10 more
wiley   +1 more source

Loneliness and rumination serially mediate the relationship between social anxiety and internet addiction among Turkish university students. [PDF]

open access: yesSci Rep
Öztekin GG   +5 more
europepmc   +1 more source

Microglial Rack1 Deficiency Alleviates Alzheimer's Disease Pathology through Enhancing IGF1‐Mediated Astrocytic Phagocytosis

open access: yesAdvanced Science, EarlyView.
Alzheimer's disease (AD) is the most common neurodegenerative disorder. This study demonstrates that microglial Rack1 deficiency decreased Aβ deposition and neuroinflammation and ameliorated cognitive impairments in AD model mice by enhancing IGF1‐mediated astrocytic phagocytosis.
Jingdan Zhang   +13 more
wiley   +1 more source

Eco-Anxiety and Environmental Guilt: A Psychological Review of Emotional Drivers in Climate Behavior [PDF]

open access: gold
Arnab Nandi Eshan   +4 more
openalex   +1 more source

Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes

open access: yesAdvanced Science, EarlyView.
In TMJ‐OA, osteoclasts play a significant role in promoting the growth of sensory nerves at the osteochondral interface. In early OA, TRAP+ osteoclast‐derived SLIT3 induces sensory nerve growth into the condylar cartilage. This nerve growth facilitates the development of pain associated with OA.
Weiwei Zhu   +13 more
wiley   +1 more source

Chronic Cannabis Extract Modulates Anxiety Behavior in Wistar Rats: VTA Histology and Catecholamine Analysis

open access: diamond
I.I. Nkanu   +6 more
openalex   +2 more sources

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